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OncoImmunology Volume 5, 2016 - Issue 3
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Original Research

Anti-CCR4 monoclonal antibody enhances antitumor immunity by modulating tumor-infiltrating Tregs in an ovarian cancer xenograft humanized mouse model

De-Kuan ChangDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA;Department of Medicine, Harvard Medical School, Boston, MA, USA
,
Eric PetersonDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA
,
Jiusong SunDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA
,
Calum GoudieDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA
,
Ronny I. DrapkinDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA;Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA;Ovarian Cancer Research Center, Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
,
Joyce F. LiuDepartment of Medicine, Harvard Medical School, Boston, MA, USA;Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
,
Ursula MatulonisDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA
,
Quan ZhuDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA;Department of Medicine, Harvard Medical School, Boston, MA, USA
&
Wayne A. MarascoDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA;Department of Medicine, Harvard Medical School, Boston, MA, USACorrespondence[email protected]
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Article: e1090075 | Received 24 Jun 2015, Accepted 29 Aug 2015, Published online: 21 Mar 2016

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