Advanced search
Publication Cover
OncoImmunology Volume 7, 2018 - Issue 4
Submit an article Journal homepage
3,294
Views
15
CrossRef citations to date
0
Altmetric
Original Research

S100A4 blockage alleviates agonistic anti-CD137 antibody-induced liver pathology without disruption of antitumor immunity

Jinhua ZhangKey Laboratory of Protein and Peptide Pharmaceuticals, CAS Center for Excellence in Biomacromolecules, Chinese Academy of Sciences-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, ChinaORCID Iconhttps://orcid.org/0000-0003-3291-8126View further author information
ORCID Icon,
Kun SongKey Laboratory of Protein and Peptide Pharmaceuticals, CAS Center for Excellence in Biomacromolecules, Chinese Academy of Sciences-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;University of Chinese Academy of Sciences, Beijing, ChinaView further author information
,
Jun WangDepartment of Immunobiology and Yale Cancer Center, Yale University School of Medicine, New Haven, CT, USAView further author information
,
Yanan LiKey Laboratory of Protein and Peptide Pharmaceuticals, CAS Center for Excellence in Biomacromolecules, Chinese Academy of Sciences-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;University of Chinese Academy of Sciences, Beijing, ChinaView further author information
,
Shuangqing LiuKey Laboratory of Protein and Peptide Pharmaceuticals, CAS Center for Excellence in Biomacromolecules, Chinese Academy of Sciences-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;University of Chinese Academy of Sciences, Beijing, ChinaView further author information
,
Chengliang DaiKey Laboratory of Protein and Peptide Pharmaceuticals, CAS Center for Excellence in Biomacromolecules, Chinese Academy of Sciences-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;University of Chinese Academy of Sciences, Beijing, ChinaView further author information
,
Lieping ChenDepartment of Immunobiology and Yale Cancer Center, Yale University School of Medicine, New Haven, CT, USAORCID Iconhttps://orcid.org/0000-0002-6825-3069View further author information
ORCID Icon,
Shengdian WangKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, ChinaView further author information
&
Zhihai QinKey Laboratory of Protein and Peptide Pharmaceuticals, CAS Center for Excellence in Biomacromolecules, Chinese Academy of Sciences-University of Tokyo Joint Laboratory of Structural Virology and Immunology, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China;Medical Research Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, ChinaCorrespondence[email protected]
View further author information
 show all
Article: e1296996 | Received 31 Oct 2016, Accepted 14 Feb 2017, Published online: 23 Jan 2018

Citations (15)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Christina Claus, Claudia Ferrara-Koller & Christian Klein. (2023) The emerging landscape of novel 4-1BB (CD137) agonistic drugs for cancer immunotherapy. mAbs 15:1.
Read now
Yanan Li, Jun Wang, Kun Song, Shuangqing Liu, Huilei Zhang, Fei Wang, Chen Ni, Wenlong Zhai, Jialu Liang, Zhihai Qin & Jinhua Zhang. (2020) S100A4 promotes hepatocellular carcinogenesis by intensifying fibrosis-associated cancer cell stemness. OncoImmunology 9:1.
Read now

Articles from other publishers (13)

Osman Dadas, Ayse Ertay & Mark S. Cragg. (2023) Delivering co-stimulatory tumor necrosis factor receptor agonism for cancer immunotherapy: past, current and future perspectives. Frontiers in Immunology 14.
Crossref
Xiangyi Gao & Ming Wang. 2023. Encyclopedia of Nanomaterials. Encyclopedia of Nanomaterials 590 603 .
Miaomiao Wei, Xinlong Yan, Xin Xin, Haiqiang Chen, Lingling Hou & Jinhua Zhang. (2022) Hepatocyte-Specific Smad4 Deficiency Alleviates Liver Fibrosis via the p38/p65 Pathway. International Journal of Molecular Sciences 23:19, pages 11696.
Crossref
Yue Fei, Qi Liu, Na Peng, Guocan Yang, Ziwei Shen, Pan Hong, Shengjun Wang, Ke Rui & Dawei Cui. (2022) Exosomes as Crucial Players in Pathogenesis of Systemic Lupus Erythematosus. Journal of Immunology Research 2022, pages 1-10.
Crossref
Jie Zhang, Yu Liu, Haiqiang Chen, Qi Yuan, Jinyan Wang, Meng Niu, Lingling Hou, Jianchun Gu & Jinhua Zhang. (2022) MyD88 in hepatic stellate cells enhances liver fibrosis via promoting macrophage M1 polarization. Cell Death & Disease 13:4.
Crossref
Dae Ho Lee. (2021) Update of early phase clinical trials in cancer immunotherapy. BMB Reports 54:1, pages 70-88.
Crossref
Anne Yau, Jinhyung Lee & Yupeng Chen. (2021) Nanomaterials for Protein Delivery in Anticancer Applications. Pharmaceutics 13:2, pages 155.
Crossref
Aung M. Tun & Stephen M. Ansell. (2020) Immunotherapy in Hodgkin and non-Hodgkin lymphoma: Innate, adaptive and targeted immunological strategies. Cancer Treatment Reviews 88, pages 102042.
Crossref
John Timmerman, Charles Herbaux, Vincent Ribrag, Andrew D. Zelenetz, Roch Houot, Sattva S. Neelapu, Theodore Logan, Izidore S. Lossos, Walter Urba, Gilles Salles, Radhakrishnan Ramchandren, Caron Jacobson, John Godwin, Cecilia Carpio, Deanne Lathers, Yali Liu, Jaclyn Neely, Satyendra Suryawanshi, Yoshinobu Koguchi & Ronald Levy. (2020) Urelumab alone or in combination with rituximab in patients with relapsed or refractory B‐cell lymphoma. American Journal of Hematology 95:5, pages 510-520.
Crossref
Tina Tianjiao Su, Xiaobin Gao & Jun Wang. (2019) A Tumor-Localized Approach to Bypass Anti-4-1BB Immuno-Toxicity. Clinical Cancer Research 25:19, pages 5732-5734.
Crossref
Qi Yuan, Shasha Hou, Junfeng Zhai, Tian Tian, Yingjie Wu, Zhenlong Wu, Jinsheng He, Zhinan Chen & Jinhua Zhang. (2019) S100A4 promotes inflammation but suppresses lipid accumulation via the STAT3 pathway in chronic ethanol-induced fatty liver. Journal of Molecular Medicine 97:10, pages 1399-1412.
Crossref
Xinyue Qi, Fanlin Li, Yi Wu, Chen Cheng, Ping Han, Jieyi Wang & Xuanming Yang. (2019) Optimization of 4-1BB antibody for cancer immunotherapy by balancing agonistic strength with FcγR affinity. Nature Communications 10:1.
Crossref
Dinh-Toi Chu, Nguyen Duy Bac, Khanh-Hoang Nguyen, Nguyen Le Bao Tien, Vo Van Thanh, Vu Thi Nga, Vo Truong Nhu Ngoc, Duong Thi Anh Dao, Le Ngoc Hoan, Nguyen Phuc Hung, Nguyen Thi Trung Thu, Van-Huy Pham, Le Nguyen Vu, Thuy Anh Vu Pham & Deepak B. Thimiri Govinda Raj. (2019) An Update on Anti-CD137 Antibodies in Immunotherapies for Cancer. International Journal of Molecular Sciences 20:8, pages 1822.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.