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OncoImmunology Volume 6, 2017 - Issue 5
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Original Research

Maternal microchimerism is prevalent in cord blood in memory T cells and other cell subsets, and persists post-transplant

Sami B. KanaanClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USACorrespondence[email protected]
,
Hilary S. GammillObstetrics and Gynecology, University of Washington, Seattle, WA, USA
,
Whitney E. HarringtonPediatrics, University of Washington, Seattle, WA, USA
,
Stephen C. De RosaVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
,
Philip A. StevensonClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
,
Alexandra M. ForsythClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
,
Judy AllenClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
,
Emma CousinClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
,
Koen van BesienDivision of Hematology/Oncology, Weill Cornell Medical College, New York, NY, USA
,
Colleen S. DelaneyClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA;Department of Medicine, University of Washington, Seattle, WA, USA
&
J. Lee NelsonClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA;Department of Medicine, University of Washington, Seattle, WA, USA
 show all
Article: e1311436 | Received 09 Jan 2017, Accepted 22 Mar 2017, Published online: 08 May 2017

Citations (34)

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Nina Orfali & Koen van Besien. (2020) Combining haplo-identical and cord blood stem cell grafts – might the whole be greater than the sum of its parts?. Leukemia & Lymphoma 61:4, pages 753-756.
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Articles from other publishers (33)

Bahaa Abu-Raya, Mirjam J. Esser, Eve Nakabembe, Jesús Reiné, Kyle Amaral, Annieck M. Diks, Esther Imede, Sing Sing Way, Ali M. Harandi, Andrew Gorringe, Kirsty Le Doare, Scott A. Halperin, Magdalena A. Berkowska & Manish Sadarangani. (2023) Antibody and B-cell Immune Responses Against Bordetella Pertussis Following Infection and Immunization. Journal of Molecular Biology 435:24, pages 168344.
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Sami B. Kanaan, Francesca Urselli, Jerald P. Radich & J. Lee Nelson. (2023) Ultrasensitive chimerism enhances measurable residual disease testing after allogeneic hematopoietic cell transplantation. Blood Advances 7:20, pages 6066-6079.
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Heidi E. Fjeldstad, Daniel P. Jacobsen, Guro M. Johnsen, Meryam Sugulle, Angel Chae, Sami B. Kanaan, Hilary S. Gammill & Anne Cathrine Staff. (2023) Poor glucose control and markers of placental dysfunction correlate with increased circulating fetal microchimerism in diabetic pregnancies. Journal of Reproductive Immunology 159, pages 104114.
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Heidi E. Fjeldstad, Daniel P. Jacobsen, Guro M. Johnsen, Meryam Sugulle, Angel Chae, Sami B. Kanaan, Hilary S. Gammill & Anne Cathrine Staff. (2023) Markers of placental function correlate with prevalence and quantity of nucleated fetal cells in maternal circulation in normotensive term pregnancies. Acta Obstetricia et Gynecologica Scandinavica 102:6, pages 690-698.
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Liwen Xiao & Fangqing Zhao. (2023) Microbial transmission, colonisation and succession: from pregnancy to infancy. Gut 72:4, pages 772-786.
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Raj Shree, Stephen McCartney, Emma Cousin, Angel Chae, Hilary S. Gammill, J. L. Nelson & Sami B. Kanaan. (2022) Umbilical Cord Maternal Microchimerism in Normal and Preeclampsia Pregnancies. Reproductive Sciences 30:4, pages 1157-1164.
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Stephen A. McCartney, Teodora Kolarova, Sami B. Kanaan, Angel Chae, Caitlin I. Laughney, J. Lee Nelson, Hilary S. Gammill & Raj Shree. (2022) Increased fetal microchimerism in immune and stem cell subsets in preeclampsia. American Journal of Reproductive Immunology 89:3.
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Kana Fujimoto, Akira Nakajima, Shohei Hori, Yumiko Tanaka, Yoshitaka Shirasaki, Sotaro Uemura & Naoki Irie. (2022) Whole-embryonic identification of maternal microchimeric cell types in mouse using single-cell RNA sequencing. Scientific Reports 12:1.
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Christina Balle, Blair Armistead, Agano Kiravu, Xiaochang Song, Anna-Ursula Happel, Angela A. Hoffmann, Sami B. Kanaan, J. Lee Nelson, Clive M. Gray, Heather B. Jaspan & Whitney E. Harrington. (2022) Factors influencing maternal microchimerism throughout infancy and its impact on infant T cell immunity. Journal of Clinical Investigation 132:13.
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Diego A. Lema, Ewa Jankowska‐Gan, Ashita Nair, Sami B. Kanaan, Christopher J. Little, David P. Foley, Afsar Raza Naqvi, Jianxin Wang, Seungpyo Hong, J. Lee Nelson, David Al‐Adra, William J. Burlingham & Jeremy A. Sullivan. (2022) Cross‐decoration of dendritic cells by non‐inherited maternal antigen‐containing extracellular vesicles: Potential mechanism for PD‐L1‐based tolerance in cord blood and organ transplantation. American Journal of Transplantation 22:5, pages 1329-1338.
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Stephanie N. Langel, Maria Blasi & Sallie R. Permar. (2022) Maternal immune protection against infectious diseases. Cell Host & Microbe 30:5, pages 660-674.
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David Wu, Sami B. Kanaan, Kelsi Penewit, Adam Waalkes, Francesca Urselli, J. Lee Nelson, Jerald Radich & Stephen J. Salipante. (2022) Ultrasensitive Quantitation of Genomic Chimerism by Single-Molecule Molecular Inversion Probe Capture and High-Throughput Sequencing of Copy Number Deletion Polymorphisms. The Journal of Molecular Diagnostics 24:2, pages 167-176.
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Sukanta Jash & Surendra Sharma. (2022) Pathogenic Infections during Pregnancy and the Consequences for Fetal Brain Development. Pathogens 11:2, pages 193.
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Donato Madalese, Roberta Penta de Vera d’Aragona, Federica Schiano di Tunnariello & Giovanna Maisto. 2022. Handbook of DNA Profiling. Handbook of DNA Profiling 645 673 .
Neta Simon, Jaclyn Shallat, John Houck, Prasanna Jagannathan, Mary Prahl, Mary K Muhindo, Abel Kakuru, Peter Olwoch, Margaret E Feeney & Whitney E Harrington. (2021) Peripheral Plasmodium falciparum Infection in Early Pregnancy Is Associated With Increased Maternal Microchimerism in the Offspring . The Journal of Infectious Diseases 224:12, pages 2105-2112.
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Karlin R. Karlmark, Marina El Haddad, Xavier-Côme Donato, Gabriel V. Martin, Florence Bretelle, Nathalie Lesavre, Jean-François Cocallemen, Marielle Martin, Christophe Picard, Tiffany Albentosa, Jean Roudier, Raoul Desbriere & Nathalie C. Lambert. (2021) Grandmaternal cells in cord blood. eBioMedicine 74, pages 103721.
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Sami B. Kanaan, Colleen Delaney, Filippo Milano, Andromachi Scaradavou, Koen van Besien, Judy Allen, Nathalie C. Lambert, Emma Cousin, Laurel A. Thur, Elena Kahn, Alexandra M. Forsyth, Oyku Sensoy & J. Lee Nelson. (2020) Cord blood maternal microchimerism following unrelated cord blood transplantation. Bone Marrow Transplantation 56:5, pages 1090-1098.
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Marina El Haddad, Karlin R. Karlmark, Xavier-Côme Donato, Gabriel V. Martin, Florence Bretelle, Nathalie Lesavre, Jean-François Cocallemen, Marielle Martin, Christophe Picard, Jean Roudier, Raoul Desbriere & Nathalie C. Lambert. (2021) Factors Predicting the Presence of Maternal Cells in Cord Blood and Associated Changes in Immune Cell Composition. Frontiers in Immunology 12.
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Tiffany D. Pan, Sami B. Kanaan, Nanette R. Lee, Josephine L. Avila, J. Lee Nelson & Dan T.A. Eisenberg. (2020) Predictors of maternal‐origin microchimerism in young women in the Philippines. American Journal of Physical Anthropology 174:2, pages 213-223.
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Donato Madalese, Roberta Penta de Vera d’Aragona, Federica Schiano di Tunnariello & Giovanna Maisto. 2020. Handbook of DNA Profiling. Handbook of DNA Profiling 1 29 .
Ok-kyong ChaekalAndromachi Scaradavou, Emeline Masson Frenet, Maria S. Albano, Melissa CushingPinkal Desai, Ludy Dobrila, Usama Gergis, Danielle Guarneri, Jing-Mei Hsu, Sangmin Lee, Sebastian A. Mayer, Adrienne A. Phillips, Nina Orfali, Ellen K. Ritchie, Gail J. Roboz, Cynthia Romeo, Michael S. Samuel, Tsiporah Shore & Koen van Besien. (2020) Adoptive immunotherapy with CB following chemotherapy for patients with refractory myeloid malignancy: chimerism and response. Blood Advances 4:20, pages 5146-5156.
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A. P. Pogribna, M. Y. Grom, I. V. Sokol, V. Berestoviy & D. O. Govsieiev. (2020) Both maternal and newborn IgMs inhibit influenza virus-induced hemagglutination in vitro. The Ukrainian Biochemical Journal 92:4, pages 35-44.
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Koen W. van Besien & Nina Orfali. (2020) Alternative Donor Transplantation for Lymphoid Malignancies: How Far We Have Come. Journal of Clinical Oncology 38:14, pages 1501-1504.
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Margaret E. Feeney. (2019) The immune response to malaria in utero . Immunological Reviews 293:1, pages 216-229.
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Cormac Cosgrove, Emilia R. Dellacecca, Joost H. van den Berg, John B. Haanen, Michael I. Nishimura, I. Caroline Le Poole & Hans E. N. Bergmans. (2019) Transgenerational transfer of gene-modified T cells. Journal for ImmunoTherapy of Cancer 7:1.
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Sami B. KanaanOyku SensoyZhen YanVijayakrishna K. GadiMichael L. RichardsonJ. Lee Nelson. (2019) Immunogenicity of a rheumatoid arthritis protective sequence when acquired through microchimerism. Proceedings of the National Academy of Sciences 116:39, pages 19600-19608.
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Anna Maria Jonsson Kanold, Magnus Westgren & Cecilia Götherström. (2018) Cellular Subsets of Maternal Microchimerism in Umbilical Cord Blood. Cell Transplantation 28:5, pages 522-528.
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Sandra Cathrine Abel Nielsen & Scott Dexter Boyd. (2019) New technologies and applications in infant B cell immunology. Current Opinion in Immunology 57, pages 53-57.
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Rianne Opstelten, Manon C. Slot, Neubury M. Lardy, Arjan C. Lankester, Arend Mulder, Frans H. J. Claas, Jon J. van Rood & Derk Amsen. (2019) Determining the extent of maternal-foetal chimerism in cord blood. Scientific Reports 9:1.
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Whitney E. Harrington, Abel Kakuru & Prasanna Jagannathan. (2019) Malaria in pregnancy shapes the development of foetal and infant immunity. Parasite Immunology 41:3, pages e12573.
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Pamela M. Odorizzi, Prasanna Jagannathan, Tara I. McIntyre, Rachel BudkerMary Prahl, Ann AumaTrevor D. Burt, Felistas NankyaMayimuna NalubegaEsther SikyomuKenneth MusinguziKate NaluwuAbel KakuruGrant Dorsey, Moses R. KamyaMargaret E. Feeney. (2018) In utero priming of highly functional effector T cell responses to human malaria. Science Translational Medicine 10:463.
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H.S. Gammill & W.E. Harrington. (2017) Microchimerism: Defining and redefining the prepregnancy context – A review. Placenta 60, pages 130-133.
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Filippo Milano, Hilary Gammill, David C. Oliver, Sami B. KanaanJ. Lee NelsonColleen Delaney. (2017) Persistence of the losing cord blood unit following double cord blood transplantation: finding the unseen. Blood 130:12, pages 1480-1482.
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