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OncoImmunology Volume 7, 2018 - Issue 2
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Original Research

Potential effect of tumor-specific Treg-targeted antibodies in the treatment of human cancers: A bioinformatics analysis

Luigi CariSection of Pharmacology, Department of Medicine, University of Perugia, Perugia, ItalyORCID Iconhttps://orcid.org/0000-0003-0698-3872
ORCID Icon,
Giuseppe NocentiniSection of Pharmacology, Department of Medicine, University of Perugia, Perugia, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5209-0488
ORCID Icon,
Graziella MiglioratiSection of Pharmacology, Department of Medicine, University of Perugia, Perugia, ItalyORCID Iconhttps://orcid.org/0000-0002-9475-6399
ORCID Icon &
Carlo RiccardiSection of Pharmacology, Department of Medicine, University of Perugia, Perugia, ItalyORCID Iconhttps://orcid.org/0000-0001-9257-3997
ORCID Icon
Article: e1387705 | Received 05 Apr 2017, Accepted 29 Sep 2017, Published online: 09 Nov 2017

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Isaure Vanmeerbeek, Jenny Sprooten, Dirk De Ruysscher, Sabine Tejpar, Peter Vandenberghe, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi & Abhishek D. Garg. (2020) Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology. OncoImmunology 9:1.
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Carlo Riccardi, Simona Ronchetti & Giuseppe Nocentini. (2018) Glucocorticoid-induced TNFR-related gene (GITR) as a therapeutic target for immunotherapy. Expert Opinion on Therapeutic Targets 22:9, pages 783-797.
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Articles from other publishers (20)

Amalia Kotsifaki, Nektarios Alevizopoulos, Vassiliki Dimopoulou & Athanasios Armakolas. (2023) Unveiling the Immune Microenvironment’s Role in Breast Cancer: A Glimpse into Promising Frontiers. International Journal of Molecular Sciences 24:20, pages 15332.
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Yue Ma, Xin Xu, Huaitao Wang, Yang Liu & Haiyan Piao. (2023) Non-coding RNA in tumor-infiltrating regulatory T cells formation and associated immunotherapy. Frontiers in Immunology 14.
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Manqi Zhou, Hao Zhang, Zilong Bai, Dylan Mann-Krzisnik, Fei Wang & Yue Li. (2023) Single-cell multi-omics topic embedding reveals cell-type-specific and COVID-19 severity-related immune signatures. Cell Reports Methods 3:8, pages 100563.
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Mahdieh Naghavi Alhosseini, Marianna Palazzo, Luigi Cari, Simona Ronchetti, Graziella Migliorati & Giuseppe Nocentini. (2023) Overexpression of Potential Markers of Regulatory and Exhausted CD8+ T Cells in the Peripheral Blood Mononuclear Cells of Patients with B-Acute Lymphoblastic Leukemia. International Journal of Molecular Sciences 24:5, pages 4526.
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Shuilian Chen, Xi Chen, Ping Zhang, Shuxia Chen, Xiao Wang, Qian Luo, Zedu Cui, Yuke Huang, Linxi Wan, Xiangtao Hou, Huan Yao, Xuan Liu, Anqi He, Zihua Jiang, Jin Qiu, Yan Li, Keming Yu & Jing Zhuang. (2022) Bioinformatics Analysis and Experimental Identification of Immune-Related Genes and Immune Cells in the Progression of Retinoblastoma. Investigative Opthalmology & Visual Science 63:11, pages 28.
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Muchun Li, Xiaozhen Zhang, Xueli Bai & Tingbo Liang. (2022) Targeting TNFR2: A Novel Breakthrough in the Treatment of Cancer. Frontiers in Oncology 12.
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方田 殷. (2022) Regulatory T Cells as Potential Therapeutic Targets for Anticancer Therapy. Advances in Clinical Medicine 12:10, pages 9267-9272.
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Qiang Fu, Qian Shen, Jin Tong, Liu Huang, Yi Cheng & Wei Zhong. (2021) Anti-Tumor Necrosis Factor Receptor 2 Antibody Combined With Anti-PD-L1 Therapy Exerts Robust Antitumor Effects in Breast Cancer. Frontiers in Cell and Developmental Biology 9.
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Shao-Dan Liu, Li-Ping Zhong, Jian He & Yong-Xiang Zhao. (2021) Targeting neuropilin-1 interactions is a promising anti-tumor strategy. Chinese Medical Journal 134:5, pages 508-517.
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Sundee Dees, Rajkumar Ganesan, Sanjaya Singh & Iqbal S. Grewal. (2020) Regulatory T cell targeting in cancer: Emerging strategies in immunotherapy. European Journal of Immunology 51:2, pages 280-291.
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Giovanni Cochetti, Luigi Cari, Giuseppe Nocentini, Vincenza Maulà, Chiara Suvieri, Rosy Cagnani, Jacopo Adolfo Rossi De Vermandois & Ettore Mearini. (2020) Detection of urinary miRNAs for diagnosis of clear cell renal cell carcinoma. Scientific Reports 10:1.
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Chunxiao Li, Ping Jiang, Shuhua Wei, Xiaofei Xu & Junjie Wang. (2020) Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects. Molecular Cancer 19:1.
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Mayanne M.T. Zhu, Samantha Burugu, Dongxia Gao, Jamie Yu, Zuzana Kos, Samuel Leung, Basil A. Horst & Torsten O. Nielsen. (2020) Evaluation of glucocorticoid-induced TNF receptor (GITR) expression in breast cancer and across multiple tumor types. Modern Pathology 33:9, pages 1753-1763.
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Luigi Cari, Pia Montanucci, Giuseppe Basta, Maria G. Petrillo, Erika Ricci, Teresa Pescara, Alessia Greco, Sabrina Cipriani, Jun Shimizu, Graziella Migliorati, Giuseppe Nocentini, Riccardo Calafiore & Carlo Riccardi. (2020) Microencapsulated G3C Hybridoma Cell Graft Delays the Onset of Spontaneous Diabetes in NOD Mice by an Expansion of Gitr+ Treg Cells. Diabetes 69:5, pages 965-980.
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Cari, De Rosa, Petrillo, Migliorati, Nocentini & Riccardi. (2019) Identification of 15 T Cell Restricted Genes Evaluates T Cell Infiltration of Human Healthy Tissues and Cancers and Shows Prognostic and Predictive Potential. International Journal of Molecular Sciences 20:20, pages 5242.
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Sebastian Chrétien, Ioannis Zerdes, Jonas Bergh, Alexios Matikas & Theodoros Foukakis. (2019) Beyond PD-1/PD-L1 Inhibition: What the Future Holds for Breast Cancer Immunotherapy. Cancers 11:5, pages 628.
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Luigi Cari, Francesca De Rosa, Giuseppe Nocentini & Carlo Riccardi. (2019) Context-Dependent Effect of Glucocorticoids on the Proliferation, Differentiation, and Apoptosis of Regulatory T Cells: A Review of the Empirical Evidence and Clinical Applications. International Journal of Molecular Sciences 20:5, pages 1142.
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Yan Wen Zhang, Qian Qian Chen, Jie Cao, Lei Qian Xu, Xin Tang, Juan Wang, Jing Zhang & Li Xia Dong. (2019) Expression of tumor necrosis factor receptor 2 in human non‐small cell lung cancer and its role as a potential prognostic biomarker. Thoracic Cancer 10:3, pages 437-444.
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Chunping Ao & Kang Zeng. (2018) The role of regulatory T cells in pathogenesis and therapy of human papillomavirus-related diseases, especially in cancer. Infection, Genetics and Evolution 65, pages 406-413.
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Yuqiao Sheng, Feng Li & Zhihai Qin. (2018) TNF Receptor 2 Makes Tumor Necrosis Factor a Friend of Tumors. Frontiers in Immunology 9.
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