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Original Research

Anti-CD47 treatment enhances anti-tumor T-cell immunity and improves immunosuppressive environment in head and neck squamous cell carcinoma

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Article: e1397248 | Received 05 Jun 2017, Accepted 21 Oct 2017, Published online: 13 Mar 2018

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Lili Sun, Xingmei Yao, Jingmei Liu, Yu Zhang & Jian Hu. (2023) Curcumin Enhances the Efficacy of Docetaxel by Promoting Anti-Tumor Immune Response in Head and Neck Squamous Cell Carcinoma. Cancer Investigation 41:5, pages 524-533.
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Articles from other publishers (33)

Yu Hao, Xinxuan Zhou, Yiling Li, Bolei Li & Lei Cheng. (2023) The CD47-SIRPα axis is a promising target for cancer immunotherapies. International Immunopharmacology 120, pages 110255.
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Shovan Dutta, Anirban Ganguly, Kaushiki Chatterjee, Sheila Spada & Sumit Mukherjee. (2023) Targets of Immune Escape Mechanisms in Cancer: Basis for Development and Evolution of Cancer Immune Checkpoint Inhibitors. Biology 12:2, pages 218.
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Kaixiao Zhou, Yabo Jiang, Shuang Feng, Tingya Wang, Lili Wang, Jianping Cao & Yang Jiao. (2022) Combining radiation with immune checkpoint inhibitors therapy for HCC: From the alteration of the immune microenvironment by radiotherapy. Radiation Medicine and Protection 3:4, pages 183-189.
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Shao-Chen Yang, Wu-Yin Wang, Jun-Jie Zhou, Lei Wu, Meng-Jie Zhang, Qi-Chao Yang, Wei-Wei Deng & Zhi-Jun Sun. (2022) Inhibition of DNMT1 potentiates antitumor immunity in oral squamous cell carcinoma. International Immunopharmacology 111, pages 109113.
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Michal Votava, Robin Bartolini, Linda Capkova, Jitka Smetanova, Vachtenheim JiriJrJr, Martin Kuchar, David Kalfert, Jan Plzak, Jirina Bartunkova & Zuzana Strizova. (2022) The expression profiles of CD47 in the tumor microenvironment of salivary gland cancers: a next step in histology-driven immunotherapy. BMC Cancer 22:1.
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Ke‐Long Zou, Zhou Lan, Hao Cui, Yu‐Yue Zhao, Wei‐Ming Wang & Guang‐Tao Yu. (2022) CD24 blockade promotes anti‐tumor immunity in oral squamous cell carcinoma . Oral Diseases.
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Junqiao Zhu, Chengyuan Cai, Jiaxin Li, Jisheng Xiao & Xiaopin Duan. (2022) CD47-SIRPα axis in cancer therapy: Precise delivery of CD47-targeted therapeutics and design of anti-phagocytic drug delivery systems. Medicine in Drug Discovery 15, pages 100139.
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Seongsik Bang, Seungyun Jee, Hwangkyu Son, Hyebin Cha, Hosub Park, Jaekyung Myung, Joo Yeon Ko, Hyunsung Kim & Seungsam Paik. (2022) CD47 Expression in Non-Melanoma Skin Cancers and Its Clinicopathological Implications. Diagnostics 12:8, pages 1859.
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Jing Huang, Fangkun Liu, Chenglong Li, Xisong Liang, Chuntao Li, Yuanyuan Liu, Zhenjie Yi, Liyang Zhang, Siqi Fu & Yu Zeng. (2022) Role of CD47 in tumor immunity: a potential target for combination therapy. Scientific Reports 12:1.
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Yuchen Wang, Chenxuan Zhao, Yang Liu, Chao Wang, Haojie Jiang, Yiqiao Hu & Jinhui Wu. (2022) Recent Advances of Tumor Therapy Based on the CD47-SIRPα Axis. Molecular Pharmaceutics 19:5, pages 1273-1293.
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Oleg Kruglov, Lisa D. S. Johnson, Angela Minic, Kimberly Jordan, Robert A. Uger, Mark Wong, Eric L. Sievers, Yaping Shou & Oleg E. Akilov. (2021) The pivotal role of cytotoxic NK cells in mediating the therapeutic effect of anti-CD47 therapy in mycosis fungoides. Cancer Immunology, Immunotherapy 71:4, pages 919-932.
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Nazli Dizman & Elizabeth I. Buchbinder. (2021) Cancer Therapy Targeting CD47/SIRPα. Cancers 13:24, pages 6229.
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Le Minh Pham, Kishwor Poudel, Cao Dai Phung, Tien Tiep Nguyen, Mahesh Pandit, Hanh Thuy Nguyen, Jae-Hoon Chang, Sung Giu Jin, Jee-Heon Jeong, Sae Kwang Ku, Han-Gon Choi, Chul Soon Yong & Jong Oh Kim. (2021) Preparation and evaluation of dabrafenib-loaded, CD47-conjugated human serum albumin-based nanoconstructs for chemoimmunomodulation. Colloids and Surfaces B: Biointerfaces 208, pages 112093.
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Karen De Vlaminck, Ema Romão, Janik Puttemans, Ana Rita Pombo Antunes, Daliya Kancheva, Isabelle Scheyltjens, Jo A. Van Ginderachter, Serge Muyldermans, Nick Devoogdt, Kiavash Movahedi & Geert Raes. (2021) Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha. Frontiers in Immunology 12.
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Robert C. Sharp, Matthew E. Brown, Melanie R. Shapiro, Amanda L. Posgai & Todd M. Brusko. (2021) The Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes. Frontiers in Immunology 12.
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Joel R. Garbow, Tanner M. Johanns, Xia Ge, John A. Engelbach, Liya Yuan, Sonika Dahiya, Christina I. Tsien, Feng Gao, Keith M. Rich & Joseph J. H. Ackerman. (2021) Irradiation-Modulated Murine Brain Microenvironment Enhances GL261-Tumor Growth and Inhibits Anti-PD-L1 Immunotherapy. Frontiers in Oncology 11.
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Marcelo M. Rodríguez, Agostina Onorato, María José Cantero, Luciana Domínguez, Juan Bayo, Esteban Fiore, Mariana García, Catalina Atorrasagasti, Ali Canbay, Mariana Malvicini & Guillermo D. Mazzolini. (2021) 4-methylumbelliferone-mediated polarization of M1 macrophages correlate with decreased hepatocellular carcinoma aggressiveness in mice. Scientific Reports 11:1.
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Yixiao Qin, Xiwang Zheng, Wei Gao, Binquan Wang & Yongyan Wu. (2021) Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma. Molecular Therapy - Oncolytics 20, pages 342-351.
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Yan Wang, Haiqing Ni, Shuaixiang Zhou, Kaijie He, Yarong Gao, Weiwei Wu, Min Wu, Zhihai Wu, Xuan Qiu, Ying Zhou, Bingliang Chen, Donghui Pan, Chenrong Huang, Mingzhu Li, Yicong Bian, Min Yang, Liyan Miao & Junjian Liu. (2020) Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity. Cancer Immunology, Immunotherapy 70:2, pages 365-376.
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Violena Pietrobon & Francesco M. Marincola. (2021) Hypoxia and the phenomenon of immune exclusion. Journal of Translational Medicine 19:1.
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Lamin B. Cham, Tom Adomati, Fanghui Li, Murtaza Ali & Karl S. Lang. (2020) CD47 as a Potential Target to Therapy for Infectious Diseases. Antibodies 9:3, pages 44.
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Ridong Feng, Hai Zhao, Jianguo Xu & Chongyang Shen. (2020) CD47: the next checkpoint target for cancer immunotherapy. Critical Reviews in Oncology/Hematology 152, pages 103014.
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Bolei Li, Min Ren, Xuedong Zhou, Qi Han & Lei Cheng. (2020) Targeting tumor-associated macrophages in head and neck squamous cell carcinoma. Oral Oncology 106, pages 104723.
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Sharareh Gholamin, Osama A Youssef, Marjan Rafat, Rogelio Esparza, Suzana Kahn, Maryam Shahin, Amato J Giaccia, Edward E Graves, Irving Weissman, Siddhartha Mitra & Samuel H Cheshier. (2019) Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma. Innate Immunity 26:2, pages 130-137.
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Wenting Zhang, Qinghua Huang, Weiwei Xiao, Yue Zhao, Jiang Pi, Huan Xu, Hongxia Zhao, Junfa Xu, Colin E. Evans & Hua Jin. (2020) Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis. Frontiers in Immunology 11.
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Y. Xiao, H. Li, L. Mao, Q.C. Yang, L.Q. Fu, C.C. Wu, B. Liu & Z.J. Sun. (2019) CD103 + T and Dendritic Cells Indicate a Favorable Prognosis in Oral Cancer . Journal of Dental Research 98:13, pages 1480-1487.
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Sabrina Pengam, Justine Durand, Claire Usal, Vanessa Gauttier, Nahzli Dilek, Bernard Martinet, Véronique Daguin, Caroline Mary, Virginie Thepenier, Géraldine Teppaz, Karine Renaudin, Gilles Blancho, Bernard Vanhove & Nicolas Poirier. (2019) SIRPα/CD47 axis controls the maintenance of transplant tolerance sustained by myeloid-derived suppressor cells. American Journal of Transplantation 19:12, pages 3263-3275.
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Lei Wu, Liang Mao, Jian-Feng Liu, Lei Chen, Guang-Tao Yu, Lei-Lei Yang, Hao Wu, Lin-Lin Bu, Ashok B. Kulkarni, Wen-Feng Zhang & Zhi-Jun Sun. (2019) Blockade of TIGIT/CD155 Signaling Reverses T-cell Exhaustion and Enhances Antitumor Capability in Head and Neck Squamous Cell Carcinoma. Cancer Immunology Research 7:10, pages 1700-1713.
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Suchismita Mohanty, Maryam Aghighi, Ketan Yerneni, Johanna Lena Theruvath & Heike E. Daldrup‐Link. (2019) Improving the efficacy of osteosarcoma therapy: combining drugs that turn cancer cell ‘don't eat me’ signals off and ‘eat me’ signals on. Molecular Oncology 13:10, pages 2049-2061.
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Karishma R. Rajani, Lucas P. Carlstrom, Ian F. Parney, Aaron J. Johnson, Arthur E. Warrington & Terry C. Burns. (2019) Harnessing Radiation Biology to Augment Immunotherapy for Glioblastoma. Frontiers in Oncology 8.
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David J. Zahavi & Louis M. Weiner. (2019) Targeting Multiple Receptors to Increase Checkpoint Blockade Efficacy. International Journal of Molecular Sciences 20:1, pages 158.
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