Advanced search
Publication Cover
OncoImmunology Volume 8, 2019 - Issue 8
Submit an article Journal homepage
3,610
Views
14
CrossRef citations to date
0
Altmetric
Original Research

Ex vivo expanded patient-derived γδ T-cell immunotherapy enhances neuroblastoma tumor regression in a murine model

Jaquelyn T. Zoinea Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA;b Cancer Biology Program, Graduate Division of Biological and Biomedical Sciences, Emory University School of Medicine, Atlanta, GA, USAView further author information
,
Kristopher A. Knighta Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USAView further author information
,
Lauren C. Fleischera Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA;c Molecular and Systems Pharmacology Program, Graduate Division of Biological and Biomedical Sciences, Emory University School of Medicine, Atlanta, GA, USAView further author information
,
Kathryn S. Suttona Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA;d Children’s Healthcare of Atlanta, Atlanta, GA, USAView further author information
,
Kelly C. Goldsmitha Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA;d Children’s Healthcare of Atlanta, Atlanta, GA, USAView further author information
,
Christopher B. Doeringa Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USAView further author information
&
H. Trent Spencera Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USACorrespondence[email protected]
View further author information
 show all
Article: 1593804 | Received 20 Nov 2018, Accepted 28 Feb 2019, Published online: 27 May 2019

Citations (14)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Adeiye A. Pilgrim, Hunter C. Jonus, Andrew Ho, Anna C. Cole, Jenny Shim & Kelly C. Goldsmith. (2023) The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1. OncoImmunology 12:1.
Read now
Hunter C. Jonus, Rebecca E. Burnham, Andrew Ho, Adeiye A. Pilgrim, Jenny Shim, Christopher B. Doering, H. Trent Spencer & Kelly C. Goldsmith. (2022) Dissecting the cellular components of ex vivo γδ T cell expansions to optimize selection of potent cell therapy donors for neuroblastoma immunotherapy trials. OncoImmunology 11:1.
Read now

Articles from other publishers (12)

Gianna M. Branella, Jasmine Y. Lee, Jennifer Okalova, Kiran K. Parwani, Jordan S. Alexander, Raquel F. Arthuzo, Andrew Fedanov, Bing Yu, David McCarty, Harrison C. Brown, Shanmuganathan Chandrakasan, Brian G. Petrich, Christopher B. Doering & H. Trent Spencer. (2023) Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia. Frontiers in Immunology 14.
Crossref
Scott A. Becker, Brian G. Petrich, Bing Yu, Kristopher A. Knight, Harrison C. Brown, Sunil S. Raikar, Christopher B. Doering & H. Trent Spencer. (2023) Enhancing the effectiveness of γδ T cells by mRNA transfection of chimeric antigen receptors or bispecific T cell engagers. Molecular Therapy - Oncolytics 29, pages 145-157.
Crossref
Yong-Liang Sha, Yun Liu, Jia-Xing Yang, Yang-Yang Wang, Bao-Cheng Gong, Yan Jin, Tong-Yuan Qu, Fan-Tong Xia, Lei Han & Qiang Zhao. (2022) B3GALT4 remodels the tumor microenvironment through GD2-mediated lipid raft formation and the c-met/AKT/mTOR/IRF-1 axis in neuroblastoma. Journal of Experimental & Clinical Cancer Research 41:1.
Crossref
Jaquelyn T. Zoine, Chengyu Prince, Jamie Y. Story, Gianna M. Branella, Allison M. Lytle, Andrew Fedanov, Jordan S. Alexander, Christopher C. Porter, Christopher B. Doering, H. Trent Spencer & Shanmuganathan Chandrakasan. (2021) Thrombopoietin-based CAR-T cells demonstrate in vitro and in vivo cytotoxicity to MPL positive acute myelogenous leukemia and hematopoietic stem cells. Gene Therapy 29:5, pages 1-12.
Crossref
Rebecca E. Burnham, Donald Tope, Gianna Branella, Erich Williams, Christopher B. Doering & H. Trent Spencer. (2021) Human serum albumin and chromatin condensation rescue ex vivo expanded γδ T cells from the effects of cryopreservation. Cryobiology 99, pages 78-87.
Crossref
Jamie Y. Story, Jaquelyn T. Zoine, Rebecca E. Burnham, Jamie A.G. Hamilton, H. Trent Spencer, Christopher B. Doering & Sunil S. Raikar. (2021) Bortezomib enhances cytotoxicity of ex vivo-expanded gamma delta T cells against acute myeloid leukemia and T-cell acute lymphoblastic leukemia. Cytotherapy 23:1, pages 12-24.
Crossref
Yixi Zhang, Pan Li, Hongyu Fang, Guocan Wang & Xun Zeng. (2020) Paving the Way Towards Universal Chimeric Antigen Receptor Therapy in Cancer Treatment: Current Landscape and Progress. Frontiers in Immunology 11.
Crossref
Yoriko Saito, Leonard D. Shultz & Fumihiko Ishikawa. (2020) Understanding Normal and Malignant Human Hematopoiesis Using Next-Generation Humanized Mice. Trends in Immunology 41:8, pages 706-720.
Crossref
Mahboubeh Yazdanifar, Giulia Barbarito, Alice Bertaina & Irma Airoldi. (2020) γδ T Cells: The Ideal Tool for Cancer Immunotherapy. Cells 9:5, pages 1305.
Crossref
Noémie Joalland & Emmanuel Scotet. (2020) Emerging Challenges of Preclinical Models of Anti-tumor Immunotherapeutic Strategies Utilizing Vγ9Vδ2 T Cells. Frontiers in Immunology 11.
Crossref
Klaus-Peter Künkele, Daniela Wesch, Hans-Heinrich Oberg, Martin Aichinger, Verena Supper & Christoph Baumann. (2020) Vγ9Vδ2 T Cells: Can We Re-Purpose a Potent Anti-Infection Mechanism for Cancer Therapy?. Cells 9:4, pages 829.
Crossref
Lauren C. Fleischer, H. Trent Spencer & Sunil S. Raikar. (2019) Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions. Journal of Hematology & Oncology 12:1.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.