Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome

Kim L. Brunekreefta Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Sterre T. Paijensa Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Maartje C.A. Woutersb Trev and Joyce Deeley Research Centre, BC Cancer, BC Cancer, Victoria, Canada

Fenne L. Komdeura Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Florine A. Egginka Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Joyce M. Lubbersa Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Hagma H. Workela Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Elisabeth C. Van Der Slikkea Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Noor E.J. Pröppera Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Ninke Leffersa Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Julien Adamc Department of Clinical Biology, Institut De Cancérologie Gustave Roussy, Paris, France

Harry Pijpera Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Annechien Plata Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Arjan Kola Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

Hans W. Nijmana Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The NetherlandsCorrespondence[email protected]

https://orcid.org/0000-0002-1821-3042

Marco De Bruyna Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, The Netherlands

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Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome

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Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome

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