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Daniel S. Lefler, Steven A. Manobianco & Babar Bashir. (2024) Immunotherapy resistance in solid tumors: mechanisms and potential solutions. Cancer Biology & Therapy 25:1.
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Ke Li, Wei Liu, Hang Yu, Jiwei Chen, Wenxuan Tang, Jianpeng Wang, Ming Qi, Yuyun Sun, Xiaoping Xu, Ji Zhang, Xinxiang Li, Weijian Guo, Xiaoling Li, Shaoli Song & Shuang Tang. (2024) 68Ga-FAPI PET imaging monitors response to combined TGF-βR inhibition and immunotherapy in metastatic colorectal cancer. Journal of Clinical Investigation 134:4.
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Debbie Robbrecht, Jean‐Jacques Grob, Oliver Bechter, Matteo Simonelli, Bernard Doger, Ivan Borbath, Marcus O. Butler, Tina Cheng, Patricia Martin Romano, Elvire Pons‐Tostivint, Massimo Di Nicola, Giuseppe Curigliano, Min‐Hee Ryu, Alejo Rodriguez‐Vida, Dirk Schadendorf, Elena Garralda, Giovanni Abbadessa, Brigitte Demers, Amele Amrate, Hong Wang, Joon Sang Lee, Robert Pomponio & Rui Wang. (2024)
Biomarker and pharmacodynamic activity of the transforming growth factor‐beta (
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Sumeet Singh, Vinita Gouri & Mukesh Samant. (2023) TGF-β in correlation with tumor progression, immunosuppression and targeted therapy in colorectal cancer. Medical Oncology 40:11.
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Letizia De Chiara, Roberto Semeraro, Benedetta Mazzinghi, Samuela Landini, Alice Molli, Giulia Antonelli, Maria Lucia Angelotti, Maria Elena Melica, Laura Maggi, Carolina Conte, Anna Julie Peired, Luigi Cirillo, Valentina Raglianti, Alberto Magi, Francesco Annunziato, Paola Romagnani & Elena Lazzeri. (2023) Polyploid tubular cells initiate a TGF-β1 controlled loop that sustains polyploidization and fibrosis after acute kidney injury. American Journal of Physiology-Cell Physiology 325:4, pages C849-C861.
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Ayanna Rohil, Siddhi Talekar, Khalid M. Shammas & Amrendra K. Ajay. (2023) Putting transcriptional brakes on fibrosis: a negative regulator of TGFβ signaling. Trends in Cell Biology 33:9, pages 734-735.
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Alessandra Castiglioni, Yagai Yang, Katherine Williams, Alvin Gogineni, Ryan S. Lane, Amber W. Wang, Justin A. Shyer, Zhe Zhang, Stephanie Mittman, Alan Gutierrez, Jillian L. Astarita, Minh Thai, Jeffrey Hung, Yeqing Angela Yang, Tony Pourmohamad, Patricia Himmels, Marco De Simone, Justin Elstrott, Aude-Hélène Capietto, Rafael Cubas, Zora Modrusan, Wendy Sandoval, James Ziai, Stephen E. Gould, Wenxian Fu, Yulei Wang, James T. Koerber, Shomyseh Sanjabi, Ira Mellman, Shannon J. Turley & Sören Müller. (2023) Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors. Nature Communications 14:1.
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Max Kam-Kwan Chan, Emily Lok-Yiu Chan, Zoey Zeyuan Ji, Alex Siu-Wing Chan, Chunjie Li, Kam-Tong Leung, Ka-Fai To & Patrick Ming-Kuen Tang. (2023) Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy. Exploration of Targeted Anti-tumor Therapy, pages 316-343.
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Mirna Burciaga-Flores, Ana Laura Márquez-Aguirre, Salvador Dueñas, Jahaziel Gasperin-Bulbarela, Alexei F. Licea-Navarro & Tanya A. Camacho-Villegas. (2023) First pan-specific vNAR against human TGF-β as a potential therapeutic application: in silico modeling assessment. Scientific Reports 13:1.
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María San-Román-Gil, Javier Torres-Jiménez, Javier Pozas, Jorge Esteban-Villarrubia, Víctor Albarrán-Fernández, Pablo Álvarez-Ballesteros, Jesús Chamorro-Pérez, Diana Rosero-Rodríguez, Inmaculada Orejana-Martín, Íñigo Martínez-Delfrade, Pablo Reguera-Puertas, Raquel Fuentes-Mateos & Reyes Ferreiro-Monteagudo. (2023) Current Landscape and Potential Challenges of Immune Checkpoint Inhibitors in Microsatellite Stable Metastatic Colorectal Carcinoma. Cancers 15:3, pages 863.
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Jing Zhang, Zhimin Hu, Calista A. Horta & Jing Yang. (2023) Regulation of epithelial-mesenchymal transition by tumor microenvironmental signals and its implication in cancer therapeutics. Seminars in Cancer Biology 88, pages 46-66.
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Yan Tie, Fan Tang, Dandan Peng, Ye Zhang & Huashan Shi. (2022) TGF-beta signal transduction: biology, function and therapy for diseases. Molecular Biomedicine 3:1.
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Anastasia E. Metropulos, Hidayatullah G. Munshi & Daniel R. Principe. (2022) The difficulty in translating the preclinical success of combined TGFβ and immune checkpoint inhibition to clinical trial. eBioMedicine 86, pages 104380.
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Max Kam-Kwan Chan, Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Alex Siu-Wing Chan, Johnny Yuk-Yeung Ho, Tony Pak-Tik Lin, Jiaoyi Chen, Kam-Tong Leung, Ka-Fai To, Hui-Yao Lan & Patrick Ming-Kuen Tang. (2022) TGF-β signaling networks in the tumor microenvironment. Cancer Letters 550, pages 215925.
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Briana G. Nixon, Shengyu Gao, Xinxin Wang & Ming O. Li. (2022) TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective. Nature Reviews Immunology.
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Alberto Mendoza-Valderrey, Maite Alvarez, Andrea De Maria, Kim Margolin, Ignacio Melero & Maria Libera Ascierto. (2022) Next Generation Immuno-Oncology Strategies: Unleashing NK Cells Activity. Cells 11:19, pages 3147.
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Yao Chen, Bingjun Bai, Kangkang Ying, Hongming Pan & Binbin Xie. (2022) Anti-PD-1 combined with targeted therapy: Theory and practice in gastric and colorectal cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877:5, pages 188775.
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Robert Pomponio, Qi Tang, Anthony Mei, Anne Caron, Bema Coulibaly, Joachim Theilhaber, Maximilian Rogers-Grazado, Michele Sanicola-Nadel, Souad Naimi, Reza Olfati-Saber, Cecile Combeau, Jack Pollard, Tun Tun Lin & Rui Wang. (2022) An integrative approach of digital image analysis and transcriptome profiling to explore potential predictive biomarkers for TGFβ blockade therapy. Acta Pharmaceutica Sinica B 12:9, pages 3594-3601.
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Dan Wang, Yuqiang Li, Heming Ge, Tarik Ghadban, Matthias Reeh & Cenap Güngör. (2022) The Extracellular Matrix: A Key Accomplice of Cancer Stem Cell Migration, Metastasis Formation, and Drug Resistance in PDAC. Cancers 14:16, pages 3998.
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Linwei Li, Qinglian Wen & Ruilin Ding. (2022) Therapeutic targeting of VEGF and/or TGF-β to enhance anti-PD-(L)1 therapy: The evidence from clinical trials. Frontiers in Oncology 12.
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Daniele V. F. Tauriello, Elena Sancho & Eduard Batlle. (2021) Overcoming TGFβ-mediated immune evasion in cancer. Nature Reviews Cancer 22:1, pages 25-44.
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Cordelia Dunai, Erik Ames, Maria C. Ochoa, Myriam Fernandez-Sendin, Ignacio Melero, Federico Simonetta, Jeanette Baker & Maite Alvarez. 2022. Adoptive Cell Transfer. Adoptive Cell Transfer
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David J. Benjamin & Yung Lyou. (2021) Advances in Immunotherapy and the TGF-β Resistance Pathway in Metastatic Bladder Cancer. Cancers 13:22, pages 5724.
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Xiaoying Li, Yueyao Yang, Qian Huang, Yu Deng, Fukun Guo, Gang Wang & Ming Liu. (2021) Crosstalk Between the Tumor Microenvironment and Cancer Cells: A Promising Predictive Biomarker for Immune Checkpoint Inhibitors. Frontiers in Cell and Developmental Biology 9.
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Vincent M. Perez, Joseph F. Kearney & Jen Jen Yeh. (2021) The PDAC Extracellular Matrix: A Review of the ECM Protein Composition, Tumor Cell Interaction, and Therapeutic Strategies. Frontiers in Oncology 11.
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Erine H Budi, Johanna R Schaub, Martin Decaris, Scott Turner & Rik Derynck. (2021)
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Ester Gonzalez-Sanchez, Javier Vaquero, Maite G. Férnandez-Barrena, Juan José Lasarte, Matías A. Avila, Pablo Sarobe, María Reig, Mariona Calvo & Isabel Fabregat. (2021) The TGF-β Pathway: A Pharmacological Target in Hepatocellular Carcinoma?. Cancers 13:13, pages 3248.
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