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OncoImmunology Volume 10, 2021 - Issue 1
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Original Research

T cells, B cells, and PD-L1 expression in esophageal and gastric adenocarcinoma before and after neoadjuvant chemotherapy: relationship with histopathological response and survival

Maria Christina Svenssona Department of Clinical Sciences, Oncology and Therapeutic Pathology, Lund University, Lund, SwedenCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6739-1171View further author information
ORCID Icon,
Albin Lindéna Department of Clinical Sciences, Oncology and Therapeutic Pathology, Lund University, Lund, SwedenView further author information
,
Jakob Nygaarda Department of Clinical Sciences, Oncology and Therapeutic Pathology, Lund University, Lund, SwedenView further author information
,
David Borga Department of Clinical Sciences, Oncology and Therapeutic Pathology, Lund University, Lund, SwedenORCID Iconhttps://orcid.org/0000-0001-9461-7391View further author information
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Charlotta Hednera Department of Clinical Sciences, Oncology and Therapeutic Pathology, Lund University, Lund, SwedenView further author information
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Björn Nodina Department of Clinical Sciences, Oncology and Therapeutic Pathology, Lund University, Lund, SwedenView further author information
,
Karin Leanderssonb Department of Clinical Sciences Lund, Oncology and Therapeutic Pathology, Lund University, Lund, SwedenORCID Iconhttps://orcid.org/0000-0001-8254-3137View further author information
ORCID Icon &
Karin Jirströma Department of Clinical Sciences, Oncology and Therapeutic Pathology, Lund University, Lund, SwedenORCID Iconhttps://orcid.org/0000-0003-2257-5000View further author information
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Article: 1921443 | Received 18 Mar 2021, Accepted 16 Apr 2021, Published online: 20 May 2021

Citations (14)

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Read on this site (1)

C. S. Weadick, A. G. Duffy & R. J. Kelly. (2022) Recent advances in immune-based approaches for the treatment of esophagogastric cancer. Expert Opinion on Emerging Drugs 27:1, pages 19-31.
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Articles from other publishers (13)

Jinfeng Zhang, Yunlong Li, Jing Chen, Tongtong Huang, Jing Lin, Yilin Pi, Huiting Hao, Dong Wang, Xiao Liang, Songbin Fu & Jingcui Yu. (2024) TOB1 modulates neutrophil phenotypes to influence gastric cancer progression and immunotherapy efficacy. Frontiers in Immunology 15.
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Giedrė Gurevičienė, Jurgita Matulionė, Lina Poškienė, Skaidrius Miliauskas & Marius Žemaitis. (2024) PD-L1 Expression and Tumour Microenvironment Patterns in Resected Non-Small-Cell Lung Cancer. Medicina 60:3, pages 482.
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James M. Lonie, Sandra Brosda, Vanessa F. Bonazzi, Lauren G. Aoude, Kalpana Patel, Ian Brown, Sowmya Sharma, Guy Lampe, Venkateswar Addala, Lambros T. Koufariotis, Scott Wood, Nicola Waddell, Riccardo Dolcetti & Andrew P. Barbour. (2023) The oesophageal adenocarcinoma tumour immune microenvironment dictates outcomes with different modalities of neoadjuvant therapy – results from the AGITG DOCTOR trial and the cancer evolution biobank. Frontiers in Immunology 14.
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Dita Ulase, Hans-Michael Behrens, Sandra Krüger, Steffen M. Heckl, Ulrike Ebert, Thomas Becker & Christoph Röcken. (2023) LAG3 in gastric cancer: it’s complicated. Journal of Cancer Research and Clinical Oncology 149:12, pages 10797-10811.
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Xie TongPeng ZhiShen Lin. (2023) Neoadjuvant Chemotherapy in Asian Patients With Locally Advanced Gastric Cancer. Journal of Gastric Cancer 23:1, pages 182.
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Yujie Wang, Peng Gao, Zhibin Hao, Ling Chen, Xiaoxiao Li, Yuan Jiao, Jingyu Liu, Jie Li, Yingyi Zhang, Xiaobo Peng, Beifang Ning & Xianbao Zhan. (2022) The effect of neoadjuvant chemotherapy on the tumor immune microenvironment in gastrointestinal tumors. Frontiers in Oncology 12.
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Yao-Hua Zhang, Jing Zeng, Xu-Sheng Liu, Yan Gao, Xue-Yan Kui, Xiao-Yu Liu, Yu Zhang & Zhi-Jun Pei. (2022) ECE2 is a prognostic biomarker associated with m6A modification and involved in immune infiltration of lung adenocarcinoma. Frontiers in Endocrinology 13.
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Yan Zhao, Yuansong Bai, Meili Shen & Yapeng Li. (2022) Therapeutic strategies for gastric cancer targeting immune cells: Future directions. Frontiers in Immunology 13.
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Holger H. Göbel, Luitpold V.R. Distel, Thomas Aigner, Maike J. Büttner-Herold & Gerhard G. Grabenbauer. (2022) PD-1 and PD-L1 expression predict regression and prognosis following neoadjuvant radiochemotherapy of oesophageal adenocarcinoma. Clinical and Translational Radiation Oncology 34, pages 90-98.
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Peter H. Goff, Laura Riolobos, Bonnie J. LaFleur, Matthew B. Spraker, Y. David Seo, Kimberly S. Smythe, Jean S. Campbell, Robert H. Pierce, Yuzheng ZhangQianchuan HeEdward Y. Kim, Stephanie K. Schaub, Gabrielle M. Kane, Jose G. Mantilla, Eleanor Y. Chen, Robert Ricciotti, Matthew J. Thompson, Lee D. CranmerMichael J. WagnerElizabeth T. Loggers, Robin L. Jones, Erin MurphyWendy M. BlumenscheinTerrill K. McClanahanJon EarlsKevin C. FlanaganNatalie A. LaFranzoTeresa S. Kim & Seth M. Pollack. (2022) Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells. Clinical Cancer Research 28:8, pages 1701-1711.
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Tanya TD Soeratram, Aafke Creemers, Sybren L Meijer, Onno J de Boer, Wim Vos, Gerrit KJ Hooijer, Mark I van Berge Henegouwen, Maarten CCM Hulshof, Jacques JGHM Bergman, Ming Lei, Maarten F Bijlsma, Bauke Ylstra, Nicole CT van Grieken & Hanneke WM van Laarhoven. (2021) Tumor‐immune landscape patterns before and after chemoradiation in resectable esophageal adenocarcinomas. The Journal of Pathology 256:3, pages 282-296.
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Hong‐mei Yin, Qiong He, Jia Chen, Zhen Li, Wanli Yang & Xiaobo Hu. (2021) Drug metabolism‐related eight‐gene signature can predict the prognosis of gastric adenocarcinoma. Journal of Clinical Laboratory Analysis 35:12.
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Zhencong Chen, Yiwei Huang, Zhengyang Hu, Mengnan Zhao, Yunyi Bian, Zongwei Chen, Yuansheng Zheng, Guoshu Bi, Yanrui Pang, Cheng Zhan, Zongwu Lin, Weigang Guo, Qun Wang & Lijie Tan. (2021) Dissecting the single-cell transcriptome network in patients with esophageal squamous cell carcinoma receiving operative paclitaxel plus platinum chemotherapy. Oncogenesis 10:10.
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