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OncoImmunology Volume 10, 2021 - Issue 1
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Prognostic biomarker

Peripheral blood and tissue assessment highlights differential tumor-circulatory gradients of IL2 and MIF with prognostic significance in resectable pancreatic ductal adenocarcinoma

Azaz Ahmeda Medical Oncology and Internal Medicine VI, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, University Heidelberg, Heidelberg, Germany;b Translational Immunotherapy, German Cancer Research Center (DKFZ), Heidelberg, GermanyView further author information
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Sophia Köhlera Medical Oncology and Internal Medicine VI, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, University Heidelberg, Heidelberg, GermanyView further author information
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Rosa Klotzc General, Visceral and Transplantation Surgery, University Hospital Heidelberg, University Heidelberg, Heidelberg, GermanyView further author information
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Nathalia Giesec General, Visceral and Transplantation Surgery, University Hospital Heidelberg, University Heidelberg, Heidelberg, GermanyView further author information
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Felix Lasitschkad Institute of Pathology, University Hospital Heidelberg, University Heidelberg, Heidelberg, GermanyView further author information
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Thilo Hackertc General, Visceral and Transplantation Surgery, University Hospital Heidelberg, University Heidelberg, Heidelberg, GermanyView further author information
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Christoph Springfelda Medical Oncology and Internal Medicine VI, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, University Heidelberg, Heidelberg, GermanyView further author information
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Inka Zörniga Medical Oncology and Internal Medicine VI, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, University Heidelberg, Heidelberg, GermanyView further author information
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Dirk Jägera Medical Oncology and Internal Medicine VI, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, University Heidelberg, Heidelberg, Germany;e Applied Tumor Immunity Clinical Cooperation Unit, National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Heidelberg, GermanyView further author information
&
Niels Halamaa Medical Oncology and Internal Medicine VI, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, University Heidelberg, Heidelberg, Germany;b Translational Immunotherapy, German Cancer Research Center (DKFZ), Heidelberg, GermanyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0344-6027View further author information
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Article: 1962135 | Received 12 May 2021, Accepted 24 Jul 2021, Published online: 10 Aug 2021

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Azaz Ahmed, Sophia Köhler, Rosa Klotz, Nathalia Giese, Thilo Hackert, Christoph Springfeld, Inka Zörnig, Dirk Jäger & Niels Halama. (2022) Tertiary lymphoid structures and their association to immune phenotypes and circulatory IL2 levels in pancreatic ductal adenocarcinoma. OncoImmunology 11:1.
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Articles from other publishers (7)

Liangliang Wu, Yiming Gao, Shengzhi Xie, Wan Ye, Yasushi Uemura, Rong Zhang, Yanju Yu, Jinfeng Li, Man Chen, Qiyan Wu, Pengfei Cui, Hongyu Liu, Shuai Mu, Yilan Li, Lingxiong Wang, Chunxi Liu, Jiahui Li, Lijun Zhang, Shunchang Jiao, Guoqing Zhang & Tianyi Liu. (2023) The level of macrophage migration inhibitory factor is negatively correlated with the efficacy of PD-1 blockade immunotherapy combined with chemotherapy as a neoadjuvant therapy for esophageal squamous cell carcinoma. Translational Oncology 37, pages 101775.
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Azaz Ahmed, Sophia Köhler, Rosa Klotz, Nathalia Giese, Thilo Hackert, Christoph Springfeld, Dirk Jäger & Niels Halama. (2023) Sex Differences in the Systemic and Local Immune Response of Pancreatic Cancer Patients. Cancers 15:6, pages 1815.
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Xin-Wen Zhang, Alexander Wald, Martin Salzmann, Niels Halama & Jessica C. Hassel. (2022) Cytokine alterations during paraneoplastic neutrophilia and leukemoid reaction in patients with advanced melanoma. Cancer Immunology, Immunotherapy 72:2, pages 509-513.
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Huizhi Sun, Runfen Cheng, Danfang Zhang, Yuhong Guo, Fan Li, Yanlei Li, Yue Li, Xiaoyu Bai, Jing Mo & Chongbiao Huang. (2023) MIF promotes cell invasion by the LRP1-uPAR interaction in pancreatic cancer cells. Frontiers in Oncology 12.
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Anna Lyubetskaya, Brian Rabe, Andrew Fisher, Anne Lewin, Isaac Neuhaus, Constance Brett, Todd Brett, Ethel Pereira, Ryan Golhar, Sami Kebede, Alba Font-Tello, Kathy Mosure, Nicholas Van Wittenberghe, Konstantinos J. Mavrakis, Kenzie MacIsaac, Benjamin J. Chen & Eugene Drokhlyansky. (2022) Assessment of spatial transcriptomics for oncology discovery. Cell Reports Methods 2:11, pages 100340.
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Azaz Ahmed, Rosa Klotz, Sophia Köhler, Nathalia Giese, Thilo Hackert, Christoph Springfeld, Dirk Jäger & Niels Halama. (2022) Immune features of the peritumoral stroma in pancreatic ductal adenocarcinoma. Frontiers in Immunology 13.
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Keywan Mortezaee & Jamal Majidpoor. (2022) Roles for macrophage-polarizing interleukins in cancer immunity and immunotherapy. Cellular Oncology 45:3, pages 333-353.
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