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Human Vaccines & Immunotherapeutics Volume 11, 2015 - Issue 10
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Research Papers

Immunogenicity and protective efficacy of an EV71 virus-like particle vaccine against lethal challenge in newborn mice

Shiyang SunSchool of Life Sciences; Jilin University; Changchun, PR China;National Engineering Laboratory for AIDS Vaccine; Jilin University; Changchun, PR China
,
Fan GaoNational Institutes for Food and Drug Control; Beijing, PR China
,
Qunying MaoNational Institutes for Food and Drug Control; Beijing, PR China
,
Jie ShaoSchool of Life Sciences; Jilin University; Changchun, PR China;National Engineering Laboratory for AIDS Vaccine; Jilin University; Changchun, PR China
,
Liping JiangSchool of Life Sciences; Jilin University; Changchun, PR China;National Engineering Laboratory for AIDS Vaccine; Jilin University; Changchun, PR China
,
Dawei LiuChangchun BCHT Biotechnology Co.; Changchun, PR China
,
Yiping WangNational Institutes for Food and Drug Control; Beijing, PR China
,
Xin YaoNational Institutes for Food and Drug Control; Beijing, PR China
,
Xing WuNational Institutes for Food and Drug Control; Beijing, PR China
,
Bo SunChangchun BCHT Biotechnology Co.; Changchun, PR China
,
Dandan ZhaoSchool of Life Sciences; Jilin University; Changchun, PR China;National Engineering Laboratory for AIDS Vaccine; Jilin University; Changchun, PR China
,
Youlei MaChangchun BCHT Biotechnology Co.; Changchun, PR China
,
Jingcai LuSchool of Life Sciences; Jilin University; Changchun, PR China;National Engineering Laboratory for AIDS Vaccine; Jilin University; Changchun, PR China
,
Wei KongSchool of Life Sciences; Jilin University; Changchun, PR China;National Engineering Laboratory for AIDS Vaccine; Jilin University; Changchun, PR China;Key Laboratory for Molecular Enzymology & Engineering; The Ministry of Education; Jilin University; Changchun, PR China
,
Chunlai JiangSchool of Life Sciences; Jilin University; Changchun, PR China;National Engineering Laboratory for AIDS Vaccine; Jilin University; Changchun, PR China;Key Laboratory for Molecular Enzymology & Engineering; The Ministry of Education; Jilin University; Changchun, PR ChinaCorrespondence[email protected] [email protected]
&
Zhenglun LiangNational Institutes for Food and Drug Control; Beijing, PR ChinaCorrespondence[email protected] [email protected]
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Pages 2406-2413 | Received 09 Feb 2015, Accepted 17 May 2015, Published online: 16 Sep 2015

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Yaqian Huo, Jinghuan Yang, Pei Liu, Bopei Cui, Chenfei Wang, Siyuan Liu, Fangyu Dong, Xujia Yan, Lianlian Bian, Fan Gao, Xing Wu, Jiuyue Zhou, Tong Cheng, Xiuling Li, Qunying Mao & Zhenglun Liang. (2021) Evaluation of the cross-neutralization activities elicited by Coxsackievirus A10 vaccine strains. Human Vaccines & Immunotherapeutics 17:12, pages 5334-5347.
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Zhijian Yang, Fan Gao, Xiaoliang Wang, Likang Shi, Zheng Zhou, Yuanxiang Jiang, Xinxing Ma, Chao Zhang, Chenliang Zhou, Xianfang Zeng, Ge Liu, Jiang Fan, Qunying Mao & Li Shi. (2020) Development and characterization of an enterovirus 71 (EV71) virus-like particles (VLPs) vaccine produced in Pichia pastoris. Human Vaccines & Immunotherapeutics 16:7, pages 1602-1610.
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Articles from other publishers (10)

Aliyu Maje Bello & Yaowaluck Maprang Roshorm. (2022) Recent progress and advances towards developing enterovirus 71 vaccines for effective protection against human hand, foot and mouth disease (HFMD). Biologicals 79, pages 1-9.
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Ziyan Wang, Chenliang Zhou, Fan Gao, Qianjun Zhu, Yuanxiang Jiang, Xinxing Ma, Yalin Hu, Likang Shi, Xiaoliang Wang, Chao Zhang, Baofeng Liu, Lianzhong Shen, Qunying Mao & Ge Liu. (2021) Preclinical evaluation of recombinant HFMD vaccine based on enterovirus 71 (EV71) virus-like particles (VLP): Immunogenicity, efficacy and toxicology. Vaccine 39:31, pages 4296-4305.
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Jiangning Liu, Binbin Zhao, Ling Xue, Jing Wu, Yanfeng Xu, Yongdong Liu & Chuan Qin. (2020) Immunization with a fusion protein vaccine candidate generated from truncated peptides of human enterovirus 71 protects mice from lethal enterovirus 71 infections. Virology Journal 17:1.
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Zhaolong Li, Chen Huan, Hong Wang, Yue Liu, Xin Liu, Xing Su, Jinghua Yu, Zhilei Zhao, Xiao‐Fang Yu, Baisong Zheng & Wenyan Zhang. (2019) TRIM 21‐mediated proteasomal degradation of SAMHD 1 regulates its antiviral activity . EMBO reports 21:1.
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Shiyang Sun, Lianlian Bian, Fan Gao, Ruixiao Du, Yalin Hu, Ying Fu, Yao Su, Xing Wu, Qunying Mao & Zhenglun Liang. (2019) A neonatal mouse model of Enterovirus D68 infection induces both interstitial pneumonia and acute flaccid myelitis. Antiviral Research 161, pages 108-115.
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Yu-Kang Chang, Kou-Huang Chen & Kow-Tong Chen. (2018) Hand, foot and mouth disease and herpangina caused by enterovirus A71 infections: a review of enterovirus A71 molecular epidemiology, pathogenesis, and current vaccine development. Revista do Instituto de Medicina Tropical de São Paulo 60:0.
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Dandan Zhao, Bo Sun, Shiyang Sun, Bin Fu, Chuntian Liu, Dawei Liu, Yanfei Chu, Youlei Ma, Lu Bai, Yongge Wu, Yan Zhou, Weiheng Su, Ali Hou, Linjun Cai, Fei Xu, Wei Kong & Chunlai Jiang. (2017) Characterization of human enterovirus71 virus-like particles used for vaccine antigens. PLOS ONE 12:7, pages e0181182.
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Eun-Je Yi, Yun-Ju Shin, Jeong-Hwan Kim, Tae-Gyun Kim & Sun-Young Chang. (2017) Enterovirus 71 infection and vaccines. Clinical and Experimental Vaccine Research 6:1, pages 4.
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Liping Jiang, Rongjun Fan, Shiyang Sun, Peihu Fan, Weiheng Su, Yan Zhou, Feng Gao, Fei Xu, Wei Kong & Chunlai Jiang. (2015) A new EV71 VP3 epitope in norovirus P particle vector displays neutralizing activity and protection in vivo in mice. Vaccine 33:48, pages 6596-6603.
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Marie-Ève Lebel, Karine Chartrand, Denis Leclerc & Alain Lamarre. (2015) Plant Viruses as Nanoparticle-Based Vaccines and Adjuvants. Vaccines 3:3, pages 620-637.
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