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Human Vaccines & Immunotherapeutics Volume 11, 2015 - Issue 8
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Research Papers

DNA vaccines targeting heavy chain C-terminal fragments of Clostridium botulinum neurotoxin serotypes A, B, and E induce potent humoral and cellular immunity and provide protection from lethal toxin challenge

Veronica L ScottDepartment of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PAUSA
,
Daniel O VillarrealDepartment of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PAUSA
,
Natalie A HutnickDepartment of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PAUSA;Janssen Research & Development; Oncology Biomarkers; Springhouse, PAUSA
,
Jewell N WaltersDepartment of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PAUSA
,
Edwin RagwanDepartment of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PAUSA
,
Khalil BdeirDepartment of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PAUSA
,
Jian YanDepartment of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PAUSA;Inovio Pharmaceuticals, Inc.; Plymouth Meeting, PAUSA
,
Niranjan Y SardesaiInovio Pharmaceuticals, Inc.; Plymouth Meeting, PAUSA
,
Adam C FinnefrockDepartment of Vaccines Research; Merck Research Laboratories; Merck & Co., Inc.; West Point, PAUSA
,
Danilo R CasimiroDepartment of Vaccines Research; Merck Research Laboratories; Merck & Co., Inc.; West Point, PAUSA
&
David B WeinerDepartment of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PAUSACorrespondence[email protected]
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Pages 1961-1971 | Received 27 Apr 2015, Accepted 22 Jun 2015, Published online: 11 Aug 2015

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Na Young Kim, Hye Bin Ahn, Chi Ho Yu, Dong Hyun Song, Gyeung Haeng Hur, Young Kee Shin & Sungho Shin. (2019) Intradermal immunization with botulinum neurotoxin serotype E DNA vaccine induces humoral and cellular immunity and protects against lethal toxin challenge. Human Vaccines & Immunotherapeutics 15:2, pages 412-419.
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Kenneth E Ugen & David B Weiner. (2015) DNA vaccines 2014 meeting: Highlights and overview. Human Vaccines & Immunotherapeutics 11:8, pages 1887-1888.
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Articles from other publishers (5)

Na Young Kim, Won Rak Son, Min Hoon Lee, Hong Seok Choi, Jun Young Choi, Young Jo Song, Chi Ho Yu, Dong Hyun Song, Gyeung Haeng Hur, Seong Tae Jeong, Sung Youl Hong, Young Kee Shin & Sungho Shin. (2022) A multipathogen DNA vaccine elicits protective immune responses against two class A bioterrorism agents, anthrax and botulism. Applied Microbiology and Biotechnology 106:4, pages 1531-1542.
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Rasetti-Escargueil & Popoff. (2019) Antibodies and Vaccines Against Botulinum Toxins: Available Measures and Novel Approaches. Toxins 11:9, pages 528.
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Bo-Yang Chen, Guo Zhou, Qing-Li Li, Jian-Sheng Lu, Dan-Yang Shi, Xiao-Bin Pang, Xiao-Wei Zhou, Yun-Zhou Yu & Pei-Tang Huang. (2017) Enhanced effects of DNA vaccine against botulinum neurotoxin serotype A by targeting antigen to dendritic cells. Immunology Letters 190, pages 118-124.
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Grace Sundeen & Joseph Barbieri. (2017) Vaccines against Botulism. Toxins 9:9, pages 268.
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A. Prisilla, R. Prathiviraj, R. Sasikala & P. Chellapandi. (2016) Structural constraints-based evaluation of immunogenic avirulent toxins from Clostridium botulinum C2 and C3 toxins as subunit vaccines. Infection, Genetics and Evolution 44, pages 17-27.
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