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Research Paper

Identification of immunoglobulin V(D)J recombinations in solid tumor specimen exome files: Evidence for high level B-cell infiltrates in breast cancer

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Pages 501-506 | Received 03 Aug 2016, Accepted 05 Oct 2016, Published online: 13 Jan 2017

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Anishaa R. Patel, Dhruv N. Patel, Yaping N. Tu, Michelle Yeagley, Andrea Chobrutskiy, Boris I. Chobrutskiy & George Blanck. (2023) Chemical complementarity between immune receptor CDR3s and candidate cancer antigens correlating with reduced survival: evidence for outcome mitigation with corticosteroid treatments. Journal of Biomolecular Structure and Dynamics 41:10, pages 4632-4640.
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Taha I. Huda, Moody Mihyu, Etienne C. Gozlan, Mary F. Arndt, Michael J. Diaz, Saif Zaman, Boris I. Chobrutskiy & George Blanck. (2021) Specific HLA alleles, paired with TCR V- and J-gene segment usage, link to distinct multiple myeloma survival rates. Leukemia & Lymphoma 62:7, pages 1711-1720.
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Toriana R. Dabkowski, Mallika Varkhedi, Joanna J. Song, Etienne C. Gozlan & George Blanck. (2023) Neuroblastoma and Glioblastoma Cases With Amplified Oncogenes Have Reduced Numbers of Tumor-Resident Adaptive Immune Receptor Recombinations. JCO Precision Oncology:7.
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Deo Rei L. Agnila, Taha I. Huda, Rachel A. Eakins, Dhruv N. Patel, Monica Hsiang, Andrea Chobrutskiy, Boris I. Chobrutskiy & George Blanck. (2023) Chemical features of melanoma tumor resident TRG CDR3s associated with better survival probabilities. Melanoma Research 33:4, pages 275-282.
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Joanna J. Song, Andrea Chobrutskiy, Boris I. Chobrutskiy, Konrad J. Cios, Taha I. Huda, Rachel A. Eakins, Michael J. Diaz & George Blanck. (2023) TRB CDR3 chemical complementarity with HBV epitopes correlates with increased hepatocellular carcinoma, disease‐free survival. Journal of Medical Virology 95:8.
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Hope J. Wolmarans, Vayda R. Barker, Andrea Chobrutskiy, Boris I. Chobrutskiy, Taha I. Huda & George Blanck. (2023) Exploiting big data survival information to unify risk-stratification related, adaptive immune receptor parameters for multiple myeloma. Genes & Immunity 24:4, pages 194-199.
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George Angelakakis, Karisa S. Serraneau, Vayda R. Barker, Blake M. Callahan, Wei Lue Tong, Saif Zaman, Taha I. Huda & George Blanck. (2022) TCR gene segment usage and HLA alleles that are associated with cancer survival rates also represent racial disparities. International Journal of Immunogenetics 50:2, pages 41-47.
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Saif ZamanBoris I. ChobrutskiyJay S. PatelAndrea DivineyYaping N. TuWei Lue TongTommy GillGeorge Blanck. (2020) Antiviral T Cell Receptor Complementarity Determining Region-3 Sequences Are Associated with a Worse Cancer Outcome: A Pancancer Analysis. Viral Immunology 33:5, pages 404-412.
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Mary L. Disis, Lauren R. Corulli, Ekram A. Gad, Marlese R. Koehnlein, Denise L. Cecil, Peter D. Senter, Shyra J. Gardai & Nicole M. Okeley. (2020) Therapeutic and Prophylactic Antitumor Activity of an Oral Inhibitor of Fucosylation in Spontaneous Mammary Cancers. Molecular Cancer Therapeutics 19:5, pages 1102-1109.
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Andrea M. Roca, Boris I. Chobrutskiy, Blake M. Callahan & George Blanck. (2019) T-cell receptor V and J usage paired with specific HLA alleles associates with distinct cervical cancer survival rates. Human Immunology 80:4, pages 237-242.
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Kendall R. Clark, Wei Lue Tong, Blake M. Callahan, John M. Yavorski, Yaping N. Tu & George Blanck. (2018) TRB‐J1 usage, in combination with the HLA‐A*01:01 allele, represents an apparent survival advantage for uterine corpus endometrial carcinoma: Comparisons with microscopic assessments of lymphocyte infiltrates. International Journal of Immunogenetics 46:1, pages 31-37.
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Blake M. Callahan, Wei Lue Tong & George Blanck. (2018) T cell receptor-β J usage, in combination with particular HLA class II alleles, correlates with better cancer survival rates. Immunologic Research 66:2, pages 219-223.
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Yaping N Tu, Wei Lue Tong, Timothy J Fawcett & George Blanck. (2017) Lung tumor exome files with T-cell receptor recombinations: a mouse model of T-cell infiltrates reflecting mutation burdens. Laboratory Investigation 97:12, pages 1516-1520.
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