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Human Vaccines & Immunotherapeutics Volume 13, 2017 - Issue 2: Tenth World Congress on Vaccines, Immunisation and Immunotherapy
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Research Papers

HPV 16 E5 oncoprotein is expressed in early stage carcinogenesis and can be a target of immunotherapy

Francesca PaoliniRegina Elena National Cancer Institute, HPV Unit, Rome, Italy
,
Gianfranca CurzioRegina Elena National Cancer Institute, HPV Unit, Rome, Italy
,
Marcelo Nazario CordeiroFederal University of Pernambuco, Department of Genetics, LEMTE, Pernambuco, Brazil
,
Silvia MassaENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, Rome, Italy
,
Luciano MarianiRegina Elena National Cancer Institute, HPV Unit, Rome, Italy
,
Fulvia PimpinelliSan Gallicano Dermatologic Institute, Rome, Italy
,
Antonio Carlos de FreitasFederal University of Pernambuco, Department of Genetics, LEMTE, Pernambuco, Brazil
,
Rosella FranconiENEA, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, C.R. Casaccia, Rome, Italy
&
Aldo VenutiRegina Elena National Cancer Institute, HPV Unit, Rome, ItalyCorrespondence[email protected]
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Pages 291-297 | Published online: 24 Jan 2017

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Satyavani Kaliamurthi, Gurudeeban Selvaraj, Aman Chandra Kaushik, Ke-Ren Gu & Dong-Qing Wei. (2018) Designing of CD8+ and CD8+-overlapped CD4+ epitope vaccine by targeting late and early proteins of human papillomavirus. Biologics: Targets and Therapy 12, pages 107-125.
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Marcelo Nazário Cordeiro, Rita de Cássia Pereira De Lima, Francesca Paolini, Alanne Rayssa da Silva Melo, Ana Paula Ferreira Campos, Aldo Venuti & Antonio Carlos De Freitas. (2018) Current research into novel therapeutic vaccines against cervical cancer. Expert Review of Anticancer Therapy 18:4, pages 365-376.
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Articles from other publishers (21)

Biqing Chen, Liping Zhao, Rulin Yang & Tianmin Xu. (2023) Advances in molecular mechanism of HPV16 E5 oncoprotein carcinogenesis. Archives of Biochemistry and Biophysics 745, pages 109716.
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Alexandre Santos Matos, Maria da Conceição Viana Invenção, Ingrid Andrêssa de Moura, Antonio Carlos de Freitas & Marcus Vinicius de Aragão Batista. (2023) Immunoinformatics applications in the development of therapeutic vaccines against human papillomavirus‐related infections and cervical cancer. Reviews in Medical Virology.
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Nabil F. Saba, Saagar Pamulapati, Bhamini Patel, Mayur Mody, Primož Strojan, Robert Takes, Antti A. Mäkitie, Oded Cohen, Pia Pace-Asciak, Jan B. Vermorken, Carol Bradford, Arlene Forastiere, Yong Teng, Andreas Wieland & Alfio Ferlito. (2023) Novel Immunotherapeutic Approaches to Treating HPV-Related Head and Neck Cancer. Cancers 15:7, pages 1959.
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Ingrid Andrêssa de Moura, Anna Jéssica Duarte Silva, Larissa Silva de Macêdo, Maria da Conceição Viana Invenção, Mylenna Máyra Gois de Sousa & Antonio Carlos de Freitas. (2022) Enhancing the Effect of Nucleic Acid Vaccines in the Treatment of HPV-Related Cancers: An Overview of Delivery Systems. Pathogens 11:12, pages 1444.
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Grégoire B. Morand, Isabel Cardona, Sara Brito Silva Costa Cruz, Alex M. Mlynarek, Michael P. Hier, Moulay A. Alaoui-Jamali & Sabrina Daniela da Silva. (2022) Therapeutic Vaccines for HPV-Associated Oropharyngeal and Cervical Cancer: The Next De-Intensification Strategy?. International Journal of Molecular Sciences 23:15, pages 8395.
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Parisa Shiri Aghbash, Milad Shirvaliloo, Ammar Khalo Abass Kasho, Farbod Alinezhad, Hans Nauwynck & Hossein Bannazadeh Baghi. (2022) Cluster of differentiation frequency on antigen presenting-cells: The next step to cervical cancer prognosis?. International Immunopharmacology 108, pages 108896.
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Yaxuan Huang, Yunyun Lan, Zhe Zhang, Xue Xiao & Tingting Huang. (2022) An Update on the Immunotherapy for Oropharyngeal Squamous Cell Carcinoma. Frontiers in Oncology 12.
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Francesca Paolini, Carla Amici, Mariantonia Carosi, Claudia Bonomo, Paola Di Bonito, Aldo Venuti & Luisa Accardi. (2021) Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors. Journal of Experimental & Clinical Cancer Research 40:1.
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Siobhan Gargan & Nigel J. Stevenson. (2021) Unravelling the Immunomodulatory Effects of Viral Ion Channels, towards the Treatment of Disease. Viruses 13:11, pages 2165.
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Danilo Ranieri, Deborah French, Salvatore Raffa, Luisa Guttieri, Maria Rosaria Torrisi & Francesca Belleudi. (2021) Expression of the E5 Oncoprotein of HPV16 Impacts on the Molecular Profiles of EMT-Related and Differentiation Genes in Ectocervical Low-Grade Lesions. International Journal of Molecular Sciences 22:12, pages 6534.
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Oscar Badillo-Godinez, Adolfo Pedroza-Saavedra, Veronica Valverde-Garduño, Victor Bermudez-Morales, Minerva Maldonado-Gama, Ricardo Leon-Letelier, Laura C. Bonifaz, Fernando Esquivel-Guadarrama & Lourdes Gutierrez-Xicotencatl. (2021) Induction of Therapeutic Protection in an HPV16-Associated Mouse Tumor Model Through Targeting the Human Papillomavirus-16 E5 Protein to Dendritic Cells. Frontiers in Immunology 12.
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Lourdes Gutierrez-Xicotencatl, Adolfo Pedroza-Saavedra, Lilia Chihu-Amparan, Azucena Salazar-Piña, Minerva Maldonado-Gama & Fernando Esquivel-Guadarrama. (2021) Cellular Functions of HPV16 E5 Oncoprotein during Oncogenic Transformation. Molecular Cancer Research 19:2, pages 167-179.
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Adrian von Witzleben, Eve Currall, Oliver Wood, Lindsey Chudley, Oluyemisi Akinyegun, Jaya Thomas, Kaïdre Bendjama, Gareth J. Thomas, Peter S. Friedmann, Emma V. King, Simon Laban & Christian H. Ottensmeier. (2021) Correlation of HPV16 Gene Status and Gene Expression With Antibody Seropositivity and TIL Status in OPSCC. Frontiers in Oncology 10.
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Zhen Dong, Renjian Hu, Yan Du, Li Tan, Lin Li, Juan Du, Longchang Bai, Yingkang Ma & Hongjuan Cui. (2021) Immunodiagnosis and Immunotherapeutics Based on Human Papillomavirus for HPV-Induced Cancers. Frontiers in Immunology 11.
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Amit Kumar Gupta & Manoj Kumar. (2020) HPVomics: An integrated resource for the human papillomavirus epitome and therapeutics. Genomics 112:6, pages 4853-4862.
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Adrian von Witzleben, Chuan Wang, Simon Laban, Natalia Savelyeva & Christian H. Ottensmeier. (2020) HNSCC: Tumour Antigens and Their Targeting by Immunotherapy. Cells 9:9, pages 2103.
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Heidar Ali Panahi, Azam Bolhassani, Gholamreza Javadi, Zahra Noormohammadi & Elnaz Agi. (2020) Development of multiepitope therapeutic vaccines against the most prevalent high-risk human papillomaviruses. Immunotherapy 12:7, pages 459-479.
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Gemma Hancock, Joshua Blight, Cesar Lopez-Camacho, Jakub Kopycinski, Mamatha Pocock, Wendy Byrne, Michael J. Price, Phillip Kemlo, Ranoromanana Ionitiana Evans, Angela Bloss, Kathryn Saunders, Richard Kirton, Monique Andersson, Karin Hellner, Arturo Reyes-Sandoval & Lucy Dorrell. (2019) A multi-genotype therapeutic human papillomavirus vaccine elicits potent T cell responses to conserved regions of early proteins. Scientific Reports 9:1.
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Chuan Wang, James Dickie, Ruhcha V. Sutavani, Catherine Pointer, Gareth J. Thomas & Natalia Savelyeva. (2018) Targeting Head and Neck Cancer by Vaccination. Frontiers in Immunology 9.
Crossref
Alexander Y. Deneka, Jeffrey C. Liu & Camille C. R. Ragin. 2018. Molecular Determinants of Head and Neck Cancer. Molecular Determinants of Head and Neck Cancer 545 583 .
Antonio Carlos de Freitas, Talita Helena Araújo de Oliveira, Marconi Rego BarrosJr.Jr. & Aldo Venuti. (2017) hrHPV E5 oncoprotein: immune evasion and related immunotherapies. Journal of Experimental & Clinical Cancer Research 36:1.
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