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Human Vaccines & Immunotherapeutics Volume 13, 2017 - Issue 9
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Research Paper

Analysis of immunological mechanisms exerted by HBsAg-HBIG therapeutic vaccine combined with Adefovir in chronic hepatitis B patients

Chenliang ZhouKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Chaofan LiKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Guo-Zhong GongThe Second Xiangya Hospital, Central South University, Changsha, People's Republic of China
,
Shuang WangKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Ji-Ming ZhangHuashan Hospital, Fudan University, Shanghai, People's Republic of China
,
Dao-Zhen XuBeijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China
,
Li-Min GuoBeijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China
,
Hong RenThe Second Affiliated Hospital, Chongqing Medical University, Chongqing, People's Republic of China
,
Min XuGuangzhou Eighth People's Hospital, Guangzhou, People's Republic of China
,
Qing XieRuijin Hospital, Jiaotong University, Shanghai, People's Republic of China
,
Chen PanFuzhou Infectious Disease Hospital, Fuzhou, People's Republic of China
,
Jie XuThe Third People's Hospital, Jiaotong University, Shanghai, People's Republic of China
,
Zhongyu HuNational Institutes for Food and Drug Control, Beijing, People's Republic of China
,
Shuang GengKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Xian ZhouKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Xianzheng WangKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Xiaoyu ZhouKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Haili MiKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Gan ZhaoKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Wencong YuKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Yu-Mei WenKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China
,
Lihua HuangWuxi Fifth People's Hospital, Wuxi, People's Republic of ChinaCorrespondence[email protected]
,
Xuan-Yi WangKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of ChinaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-6398-9184
ORCID Icon &
Bin WangKey Laboratory of Medical Molecular Virology, MoE/MoH, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of ChinaCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-9945-1818
ORCID Icon show all
Pages 1989-1996 | Received 06 Jan 2017, Accepted 24 May 2017, Published online: 12 Jul 2017

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Shaowen Jiang, Minghao Cai, Zhenglan Zhang, Cong Qian, Jiexiao Wang, Ziqiang Li, Qing Guo, Huijuan Zhou, Haiguang Xin, Wei Cai, Hui Wang, Simin Guo, Yan Huang & Qing Xie. (2023) The potential effect of HBV vaccination on off-treatment HBsAg reversion after interferon-induced HBsAg clearance. Human Vaccines & Immunotherapeutics 19:1.
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Hua-Jun Zhao, Yi-Fei Hu, Qiu-Ju Han & Jian Zhang. (2022) Innate and adaptive immune escape mechanisms of hepatitis B virus. World Journal of Gastroenterology 28:9, pages 881-896.
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Efthymios P Tsounis, Evanthia Tourkochristou, Athanasia Mouzaki & Christos Triantos. (2021) Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure. World Journal of Gastroenterology 27:21, pages 2727-2757.
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Bali Pulendran, Prabhu S. Arunachalam & Derek T. O’Hagan. (2021) Emerging concepts in the science of vaccine adjuvants. Nature Reviews Drug Discovery 20:6, pages 454-475.
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Alex F. Tang, Gospel Enyindah-Asonye & Catarina E. Hioe. (2021) Immune Complex Vaccine Strategies to Combat HIV-1 and Other Infectious Diseases. Vaccines 9:2, pages 112.
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Valeria Barili, Carolina Boni, Marzia Rossi, Andrea Vecchi, Alessandra Zecca, Amalia Penna, Gabriele Missale, Carlo Ferrari & Paola Fisicaro. (2021) Metabolic regulation of the HBV-specific T cell function. Antiviral Research 185, pages 104989.
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Wonderful Tatenda Choga, Motswedi Anderson, Edward Zumbika, Bonolo B. Phinius, Tshepiso Mbangiwa, Lynnette N. Bhebhe, Kabo Baruti, Peter Opiyo Kimathi, Kaelo K. Seatla, Rosemary M. Musonda, Trevor Graham Bell, Sikhulile Moyo, Jason T. Blackard & Simani Gaseitsiwe. (2020) In Silico Prediction of Human Leukocytes Antigen (HLA) Class II Binding Hepatitis B Virus (HBV) Peptides in Botswana. Viruses 12:7, pages 731.
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Zhongji Meng, Yuanyuan Chen & Mengji Lu. (2020) Advances in Targeting the Innate and Adaptive Immune Systems to Cure Chronic Hepatitis B Virus Infection. Frontiers in Immunology 10.
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Bisheng Shi, Yanling Wu, Chunyu Wang, Xiaofang Li, Fan Yu, Bin Wang, Zhenlin Yang, Jianhua Li, Mifang Liang, Yumei Wen, Tianlei Ying & Zhenghong Yuan. (2019) Evaluation of antiviral - passive - active immunization (“sandwich”) therapeutic strategy for functional cure of chronic hepatitis B in mice. eBioMedicine 49, pages 247-257.
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Carolina Boni, Valeria Barili, Greta Acerbi, Marzia Rossi, Andrea Vecchi, Diletta Laccabue, Amalia Penna, Gabriele Missale, Carlo Ferrari & Paola Fisicaro. (2019) HBV Immune-Therapy: From Molecular Mechanisms to Clinical Applications. International Journal of Molecular Sciences 20:11, pages 2754.
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Jing Han, Guo-Zhong Gong, Jian-Hua Lei, Wen-Jun Qin, Rui-Huan Qin, Xuan-Yi Wang, Jian-Xin Gu, Shi-Fang Ren & Yu-Mei Wen. (2019) Response to immune complex vaccine in chronic hepatitis B patients is associated with lower baseline level of serum IgG galactosylation. Medicine 98:26, pages e16208.
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Xuan-Yi Wang, Bin Wang & Yu-Mei Wen. (2019) From therapeutic antibodies to immune complex vaccines. npj Vaccines 4:1.
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Yu-mei Wen & Yan Shi. 2019. Fc Mediated Activity of Antibodies. Fc Mediated Activity of Antibodies 95 118 .

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