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A Moraxella catarrhalis vaccine to protect against otitis media and exacerbations of COPD: An update on current progress and challenges

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Pages 2322-2331 | Received 05 Apr 2017, Accepted 12 Jul 2017, Published online: 18 Oct 2017

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Oana Joean & Tobias Welte. (2022) Vaccination and modern management of chronic obstructive pulmonary disease – a narrative review. Expert Review of Respiratory Medicine 16:6, pages 605-614.
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Jillian H. Hurst & Matthew S. Kelly. (2023) Leveraging the human microbiota to target bacterial respiratory pathogens: new paths toward an expanded antimicrobial armamentarium. mBio.
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Justyna Roszkowiak, Siobhán McClean, Aleksandra M. Mirończuk & Daria Augustyniak. (2023) The Direct Anti-Virulence but Not Bactericidal Activity of Human Neutrophil Elastase against Moraxella catarrhalis. International Journal of Molecular Sciences 24:7, pages 6607.
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Denise E. Morris, Karen L. Osman, David W. Cleary & Stuart C. Clarke. (2022) The characterization of Moraxella catarrhalis carried in the general population. Microbial Genomics 8:5.
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Carine Ysebaert, Cindy Castado, Marie-Cécile Mortier, Stéphane Rioux, Christiane Feron, Emmanuel Di Paolo, Vincent Weynants, Normand Blais, Nathalie Devos & Philippe Hermand. (2021) UspA2 is a cross-protective Moraxella catarrhalis vaccine antigen. Vaccine 39:39, pages 5641-5649.
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Nirma Khatri Vadlamudi, Ariana Saatchi, David M. Patrick, Caren Rose, Mohsen Sadatsafavi & Fawziah Marra. (2021) Impact of the 13-valent pneumococcal conjugate vaccine on acute otitis media and acute sinusitis epidemiology in British Columbia, Canada. Journal of Antimicrobial Chemotherapy 76:9, pages 2419-2427.
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Aimee Tan, Luke V. Blakeway, Taha, Yuedong Yang, Yaoqi Zhou, John M. Atack, Ian R. Peak & Kate L. Seib. (2020) Moraxella catarrhalis phase-variable loci show differences in expression during conditions relevant to disease. PLOS ONE 15:6, pages e0234306.
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Arno Thibau, Alexander A. Dichter, Diana J. Vaca, Dirk Linke, Adrian Goldman & Volkhard A. J. Kempf. (2019) Immunogenicity of trimeric autotransporter adhesins and their potential as vaccine targets. Medical Microbiology and Immunology 209:3, pages 243-263.
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Xiaojing Liu, Qihang Chang, Raquel Ferrer‐Espada, Leon G. Leanse, Xueping Sharon Goh, Xiuli Wang, Jeffrey A. Gelfand & Tianhong Dai. (2020) Photoinactivation of Moraxella catarrhalis Using 405‐nm Blue Light: Implications for the Treatment of Otitis Media . Photochemistry and Photobiology 96:3, pages 611-617.
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Mark R. Alderson, Tim Murphy, Stephen I. Pelton, Laura A. Novotny, Laura L. Hammitt, Arwa Kurabi, Jian-Dong Li, Ruth B. Thornton & Lea-Ann S. Kirkham. (2020) Panel 8: Vaccines and immunology. International Journal of Pediatric Otorhinolaryngology 130, pages 109839.
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Regie Lyn P. Santos-Cortez, Mahmood F. Bhutta, Joshua P. Earl, Lena Hafrén, Michael Jennings, Joshua C. Mell, Michael E. Pichichero, Allen F. Ryan, Hilda Tateossian & Garth D. Ehrlich. (2020) Panel 3: Genomics, precision medicine and targeted therapies. International Journal of Pediatric Otorhinolaryngology 130, pages 109835.
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Elke J. Seppanen, Ruth B. Thornton, Hannah JD North, Karli J. Corscadden, Selma P. Wiertsema, Shyan Vijayasekaran, Harvey L. Coates, Peter Jacoby, Peter C. Richmond & Lea-Ann S. Kirkham. (2020) Bacterial Reservoirs in the Middle Ear of Otitis-prone Children Are Associated With Repeat Ventilation Tube Insertion. Pediatric Infectious Disease Journal 39:2, pages 91-96.
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Sanjesh Singh, Jennifer C. Wilson, Allan W. Cripps, Helen Massa, Victoria Ozberk, I. Darren Grice & Ian R. Peak. (2020) Immunological characterisation of truncated lipooligosaccharide-outer membrane protein based conjugate vaccine against Moraxella catarrhalis and nontypeable Haemophilus influenzae. Vaccine 38:2, pages 309-317.
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Adonis D’Mello, Christian P. Ahearn, Timothy F. Murphy & Hervé Tettelin. (2019) ReVac: a reverse vaccinology computational pipeline for prioritization of prokaryotic protein vaccine candidates. BMC Genomics 20:1.
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Julio C. Ramirez. (2019) 50 Years Ago in T J P. The Journal of Pediatrics 213, pages 29.
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Benno Paul Weber. (2019) Otitis media — häufig, aber nicht trivial. HNO Nachrichten 49:5, pages 18-23.
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Mina Eghbali, Majid Baserisalehi & Masood Ghane. (2019) Distribution of Virulence Genes in Moraxella catarrhalis Isolated from Clinical Samples in the North of Iran. Iranian Red Crescent Medical Journal 21:1.
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Daria Augustyniak, Justyna Roszkowiak, Izabela Wiśniewska, Jacek Skała, Daiva Gorczyca & Zuzanna Drulis-Kawa. (2018) Neuropeptides SP and CGRP Diminish the Moraxella catarrhalis Outer Membrane Vesicle- (OMV-) Triggered Inflammatory Response of Human A549 Epithelial Cells and Neutrophils . Mediators of Inflammation 2018, pages 1-15.
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Влада Шмыленко, Vlada Shmylenko, Альбина Бондаренко, Albina Bondarenko, Ольга Троценко, Olga Trotsenko, Вячеслав Туркутюков & Vyacheslav Turkutyukov. (2018) FREQUENCY OF DETECTION OF MORAXELLA CATARRHALIS IN CHILDREN WITH A RECURRENT COURSE OF RESPIRATORY DISEASES IN KHABAROVSK CITY DURING 2016-2017. Bulletin physiology and pathology of respiration 1:68, pages 52-56.
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