5,568
Views
60
CrossRef citations to date
0
Altmetric
Review

HPV-related oropharyngeal cancer: a review on burden of the disease and opportunities for prevention and early detection

ORCID Icon, , , , &
Pages 1920-1928 | Received 01 Oct 2018, Accepted 23 Mar 2019, Published online: 07 May 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Andrew Halverson, Mark Mintline, Fanglong Dong & Elizabeth Andrews. (2023) C.E. Credit. Assessment of Pre-Doctoral Dental Students’ Knowledge, Attitudes, and Beliefs of HPV-Related Diseases and Vaccination Trends. Journal of the California Dental Association 51:1.
Read now
Miłosz Pinkiewicz, Karolina Dorobisz & Tomasz Zatoński. (2022) Human Papillomavirus-Associated Head and Neck Cancers. Where are We Now? A Systematic Review. Cancer Management and Research 14, pages 3313-3324.
Read now
Hui-Ching Lau, Yujie Shen, Huiying Huang, Xiaohui Yuan, Mengyou Ji, Hongli Gong, Chi-Yao Hsueh & Liang Zhou. (2022) Cross-comparison of microbiota in the oropharynx, hypopharyngeal squamous cell carcinoma and their adjacent tissues through quantitative microbiome profiling. Journal of Oral Microbiology 14:1.
Read now
Kyle Jones. (2021) The Role of Dental Professionals in the Early Detection of Oral Cancer. Journal of the California Dental Association 49:4, pages 215-222.
Read now
Gregory D. Zimet & Nosayaba Osazuwa-Peters. (2019) There’s Much Yet to be Done: Diverse Perspectives on HPV Vaccination. Human Vaccines & Immunotherapeutics 15:7-8, pages 1459-1464.
Read now

Articles from other publishers (55)

Jeffrey M. Skolnik & Matthew P. Morrow. (2023) Vaccines for HPV-associated diseases. Molecular Aspects of Medicine 94, pages 101224.
Crossref
Tomasz Sobierajski, Piotr Rzymski, Ilona Małecka & Ewa Augustynowicz. (2023) Trust in Physicians in the Context of HPV Vaccination of Children from the Perspective of Social Exchange Theory: A Representative Study of Polish Parents. Vaccines 11:10, pages 1618.
Crossref
Mi Jung Kwon, Ha Young Park, Joong Seob Lee, Eun Soo Kim, Nan Young Kim, Eun Sook Nam, Seong Jin Cho & Ho Suk Kang. (2023) Dysregulated microRNA Expression Relevant to TERT Promoter Mutations in Tonsil Cancer—A Pilot Study. Life 13:10, pages 2090.
Crossref
Carlos Enrique Galeana-Patiño, Mario Isidoro Ortiz, Raquel Cariño-Cortés, Iris Cristina López-Santillán, Javier Castro-Rosas, Carlos Alberto Gómez-Aldapa & Víctor Manuel Muñoz-Pérez. (2023) Probiotics, as Adjuvant Therapy and Preventive Measure on Progression, and Complications of Head and Neck Cancer. Current Pharmaceutical Biotechnology 24:12, pages 1504-1514.
Crossref
Mohamed Toufic El Hussein & Simreen Dhaliwal. (2023) HPV vaccination for prevention of head and neck cancer among men. The Nurse Practitioner 48:10, pages 25-32.
Crossref
Pujan Rai, Charlene E. Goh, Francine Seah, Intekhab Islam, Wendy Wang Chia-Wei, Philip Martin Mcloughlin & John Ser Pheng Loh. (2023) Oral Cancer Awareness of Tertiary Education Students and General Public in Singapore. International Dental Journal 73:5, pages 651-658.
Crossref
Kim-Phuong Truong-Vu. (2023) Racial, Ethnic, and Gender Differences in the Timing of Initiating the HPV Vaccine in the United States: the Case of Southeast Asian Americans. Journal of Racial and Ethnic Health Disparities.
Crossref
Beth I. Schwartz, Merissa Maccani, Shalini Bansal & Meghan Gannon. (2023) Parental perceptions of the HPV vaccine for prevention of anogenital and oropharyngeal cancers. Vaccine: X 14, pages 100298.
Crossref
Xiangqun Ju, Sneha Sethi, Annika Antonsson, Joanne Hedges, Karen Canfell, Megan Smith, Gail Garvey, Richard M. Logan & Lisa M. Jamieson. (2023) Natural History of Oral HPV Infection among Indigenous South Australians. Viruses 15:7, pages 1573.
Crossref
Manli Guo, Lijie Zhang, Huihui Wang, Qiaozhen Zhou, Xinrang Zhu, Xinyu Fu, Jinlong Yang, Shanhe Liu, Dingcheng Guo & Baoping Zhang. (2023) SOCS1 as a Biomarker Candidate for HPV Infection and Prognosis of Head and Neck Squamous Cell Carcinomas. Current Issues in Molecular Biology 45:7, pages 5598-5612.
Crossref
Maria Teresa Bruno, Sara Boemi, Giuseppe Caruso, Francesco Sgalambro, Salvatore Ferlito, Antonio Cavallaro, Maria Chiara Sudano & Marco Palumbo. (2023) Oral HPV Infection in Women with HPV-Positive Cervix Is Closely Related to Oral Sex. Diagnostics 13:12, pages 2096.
Crossref
Federica Di Spirito, Alessandra Amato, Francesco D’Ambrosio, Davide Cannatà, Maria Pia Di Palo, Nicoletta Coppola & Massimo Amato. (2023) HPV-Related Oral Lesions: YouTube Videos Suitability for Preventive Interventions including Mass-Reach Health Communication and Promotion of HPV Vaccination. International Journal of Environmental Research and Public Health 20:11, pages 5972.
Crossref
Federica Di Spirito. (2023) Human Papillomavirus: Oral Lesions and Vaccination. Cancers 15:10, pages 2711.
Crossref
Philip Macilwraith, Eve Malsem & Sathana Dushyanthen. (2023) The effectiveness of HPV vaccination on the incidence of oropharyngeal cancers in men: a review. Infectious Agents and Cancer 18:1.
Crossref
I. Niles Zoschke, Sarah L. Bennis, J. Michael Wilkerson, Cynthia L. Stull, Alan G. Nyitray, Samir S. Khariwala, C. Mark Nichols, B. R. Simon Rosser, Charlene Flash & Michael W. Ross. (2023) HPV-related oropharyngeal cancer early detection in gay and bisexual men is an “orphan” practice: A qualitative analysis among healthcare providers. Frontiers in Public Health 11.
Crossref
Hongyang Lu. (2023) Prevention and Control of Infectious Diseases. Highlights in Science, Engineering and Technology 36, pages 871-874.
Crossref
Ha Young Park, Joong Seob Lee, Jee Hye Wee, Jeong Wook Kang, Eun Soo Kim, Taeryool Koo, Hee Sung Hwang, Hyo Jung Kim, Ho Suk Kang, Hyun Lim, Nan Young Kim, Eun Sook Nam, Seong Jin Cho & Mi Jung Kwon. (2023) Assessment of the Mutation Profile of Tonsillar Squamous Cell Carcinomas Using Targeted Next-Generation Sequencing. Biomedicines 11:3, pages 851.
Crossref
Vincenzo Restivo, Giuseppa Minutolo, Marianna Maranto, Antonio Maiorana, Francesco Vitale, Alessandra Casuccio & Emanuele Amodio. (2023) Impact of Preventive Strategies on HPV-Related Diseases: Ten-Year Data from the Italian Hospital Admission Registry. Cancers 15:5, pages 1452.
Crossref
Jimoh Amzat, Kehinde Kazeem Kanmodi, Kafayat Aminu & Eyinade Adeduntan Egbedina. (2023) School-Based Interventions on Human Papillomavirus in Africa: A Systematic Scoping Review. Venereology 2:1, pages 43-58.
Crossref
Teresa K.L. Boitano, Peter W. Ketch, Isabel C. Scarinci & Warner K. Huh. (2023) An Update on Human Papillomavirus Vaccination in the United States. Obstetrics & Gynecology 141:2, pages 324-330.
Crossref
Sh. I. Musin, A. V. Sultanbaev, K. V. Menshikov, L. K. Zakirova, F. F. Mufazalov, I. A. Sharifgaliev, A. F. Nasretdinov, S. V. Osokin, N. A. Sharafutdinova, V. V. Ilyin, D. O. Lipatov, M. V. Sultanbaev & T. E. Timin. (2023) Oropharyngeal cancer diagnosis and treatment in actual clinical practice in the Republic of Bashkortostan: analysis for 2020. Creative surgery and oncology 12:4, pages 267-274.
Crossref
Indu Sharma, Anuradha Sharma, Reena Tomer, Neha Negi & Ranbir Chander Sobti. 2023. Handbook of Oncobiology: From Basic to Clinical Sciences. Handbook of Oncobiology: From Basic to Clinical Sciences 1 29 .
Jooin Bang, Hye Lim Park, Ie Ryung Yoo, Hyun-Il Shin, Geun-Jeon Kim, Dong-Il Sun & Sang-Yeon Kim. (2022) Predictive Value of 18F-Fluorodeoxyglucose Positron-Emission Tomography Metabolic and Volumetric Parameters for Systemic Metastasis in Tonsillar Cancer. Cancers 14:24, pages 6242.
Crossref
Bailey Hassman, Maranda Thompson & Zafar Sayed. (2022) Perifacial Lymph Node Metastasis After Treatment of Oropharyngeal Primary Malignancy: A Case Report. Cureus.
Crossref
Ermelinda Monti, Giussy Barbara, Giada Libutti, Veronica Boero, Fabio Parazzini, Andrea Ciavattini, Giorgio Bogani, Lorenzo Pignataro, Beatrice Magni, Camilla Erminia Maria Merli & Paolo Vercellini. (2022) A clinician’s dilemma: what should be communicated to women with oncogenic genital HPV and their partners regarding the risk of oral viral transmission?. BMC Women's Health 22:1.
Crossref
Zhen Zeng. (2022) Impact of Status quo and Resistance to Innovation on the Failure of Detection and Prevention Strategies of Drugs Control Committee in Malaysia. Frontiers in Psychology 13.
Crossref
Xuelan Zeng, Liang Peng, Weiping Wen & Wei Sun. (2021) Comparison of Survival of Patients With T 1 ‐2 cN 0 Oropharyngeal Cancer Treated With or Without Elective Neck Dissection . The Laryngoscope 132:6, pages 1205-1212.
Crossref
Gilla Shapiro. (2022) HPV Vaccination: An Underused Strategy for the Prevention of Cancer. Current Oncology 29:5, pages 3780-3792.
Crossref
Na Liu, Feng Shi, Lifang Yang, Weihua Liao & Ya Cao. (2022) Oncogenic viral infection and amino acid metabolism in cancer progression: Molecular insights and clinical implications. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877:3, pages 188724.
Crossref
Nooshin Mohtasham, Farnaz Mohajer Tehran & Hamid Abbaszadeh. (2022) Head and neck cancer organoids as a promising tool for personalized cancer therapy: A literature review. Health Science Reports 5:3.
Crossref
Jordi Rubió-Casadevall, Elna Ciurana, Montserrat Puigdemont, Arantza Sanvisens, Jordi Marruecos, Josefina Miró, Antoni Urban, Rosa-Lisset Palhua, Ferran Martín-Romero, Maria Rosa Ortiz-Duran & Rafael Marcos-Gragera. (2022) Population-Based Analysis of Trends in Incidence and Survival of Human Papilloma Virus-Related Oropharyngeal Cancer in a Low-Burden Region of Southern Europe. International Journal of Environmental Research and Public Health 19:8, pages 4802.
Crossref
Melissa Solomon Kornhaber, Taylor Florence, Trexton Davis & Karl Kingsley. (2022) Assessment of Oral Human Papillomavirus Prevalence in Pediatric and Adult Patients within a Multi-Ethnic Clinic Population. Dentistry Journal 10:4, pages 54.
Crossref
Edith Morais, Smita Kothari, Craig Roberts, Glorian Yen, Ya-Ting Chen, Mark Lynam, Montse Pedrós, Haitham Mirghani, Laia Alemany, Miquel Angel Pavon, Tim Waterboer, Hisham Mehanna & Anna R. Giuliano. (2022) Oral human papillomavirus (HPV) and associated factors among healthy populations: The design of the PROGRESS (PRevalence of Oral hpv infection, a Global aSSessment) study. Contemporary Clinical Trials 115, pages 106630.
Crossref
Faris F. Brkic, Stefan Stoiber, Tobias Maier, Elisabeth Gurnhofer, Lukas Kenner, Gregor Heiduschka & Lorenz Kadletz-Wanke. (2022) Targeting Wnt/Beta-Catenin Signaling in HPV-Positive Head and Neck Squamous Cell Carcinoma. Pharmaceuticals 15:3, pages 378.
Crossref
Rafael Cardoso Pires, Raiany Carvalho, Ricardo Ribeiro Gama, André Lopes Carvalho, Carlos Roberto Santos & Renato de Castro Capuzzo. (2021) Progressive Increase Trend in HPV-Related Oropharyngeal Squamous Cell Carcinoma in Brazil. International Archives of Otorhinolaryngology 26:01, pages e132-e136.
Crossref
Chi-Hong Duong, Judith E. Mueller, Pascale Tubert-Bitter & Sylvie Escolano. (2022) Estimation of mid-and long-term benefits and hypothetical risk of Guillain-Barre syndrome after human papillomavirus vaccination among boys in France: A simulation study. Vaccine 40:2, pages 359-363.
Crossref
Anna Jaakola, Michel Roger, Marie-Claude Faucher, Kari Syrjänen, Seija Grénman, Stina Syrjänen & Karolina Louvanto. (2021) HLA-G polymorphism impacts the outcome of oral HPV infections in women. BMC Infectious Diseases 21:1.
Crossref
Teresa K.L. Boitano, Casey Daniel, Young-il Kim, J. Michael StraughnJrJr, Sylvia Peral & Isabel Scarinci. (2021) Beyond words: Parental perceptions on human papilloma virus vaccination recommendations and its impact on uptake. Preventive Medicine Reports 24, pages 101596.
Crossref
Pawel Golusinski, June Corry, Vincent Vander Poorten, Ricard Simo, Elisabeth Sjögren, Antti Mäkitie, Luis Paulo Kowalski, Johannes Langendijk, Boudewijn J.M. Braakhuis, Robert P. Takes, Andrés Coca-Pelaz, Juan P. Rodrigo, Stefan M. Willems, Arlene A. Forastiere, Remco De Bree, Nabil F. Saba, Yong Teng, Alvaro Sanabria, Pasquale Di Maio, Mateusz Szewczyk & Alfio Ferlito. (2021) De-escalation studies in HPV-positive oropharyngeal cancer: How should we proceed?. Oral Oncology 123, pages 105620.
Crossref
Glória Maria de França, Ana Claudia de Macedo Andrade, Fernanda Aragão Felix, Weslay Rodrigues da Silva, Dennys Ramon de Melo Fernandes Almeida, Rafaella Bastos Leite, Hébel Cavalcanti Galvão & Márcia Cristina da Costa Miguel. (2021) Survival-related epithelial-mesenchymal transition proteins in oropharyngeal squamous cell carcinoma: A systematic review and meta-analysis. Archives of Oral Biology 131, pages 105267.
Crossref
Alexandre Bozec, Dorian Culié, Gilles Poissonnet, François Demard & Olivier Dassonville. (2021) Current Therapeutic Strategies in Patients with Oropharyngeal Squamous Cell Carcinoma: Impact of the Tumor HPV Status. Cancers 13:21, pages 5456.
Crossref
Jaromír Astl, Richard Holy, Eva Maute, Jan Rotnágl, David Kalfeřt, Barbora Drnková, Temoore Younus & Emil Pavlík. (2021) Genome of Helicobacter pylori and Serotype of HPV Detected in Oropharyngeal and Laryngeal Cancer and Chronic Inflammation Patients. International Journal of Environmental Research and Public Health 18:18, pages 9545.
Crossref
Carlo Bosoni, Michele Pietragalla, Davide Maraghelli, Vieri Rastrelli, Luca Giovanni Locatello, Isacco Desideri, Veronica Giuntini, Lorenzo Franchi & Cosimo Nardi. (2021) Is Panoramic Radiography Really a Key Examination before Chemo-Radiotherapy Treatment for Oropharyngeal Cancer?. Applied Sciences 11:17, pages 7965.
Crossref
Tatiana E. Privalova, Olga V. Surovtseva & Dmitry V. Andriyanov. (2021) Benefits of Gender-Neutral Vaccination Strategy for the Prevention of HPV-Associated Diseases and the Eradication of HPV Infection in General. Current State of HPV Vaccination in the World. Pediatric pharmacology 18:3, pages 239-244.
Crossref
Chloé Molimard, Virginie L’Huillier, Alexis Overs, Christine Soret, Marie-Paule Algros, Christiane Mougin, David Guenat, Olivier Mauvais & Jean-Luc Prétet. (2021) Human papillomavirus DNA and p16 expression in head and neck squamous cell carcinoma in young French patients. Journal of International Medical Research 49:7, pages 030006052110225.
Crossref
Jiye Zhang, Zhilin Qin, Chaoyong Lou, Jing Huang & Youfu Xiong. (2021) The efficacy of vaccination to prevent human papilloma viruses infection at anal and oral: a systematic review and meta-analysis. Public Health 196, pages 165-171.
Crossref
Christina Uwins, Sunu Cyriac & Geetu Bhandoria. (2021) HPV vaccine: Expanding indications and global disparity. Vaccine 39:29, pages 3787-3789.
Crossref
Lejla Mahmutović, Esma Bilajac & Altijana Hromić-Jahjefendić. (2021) Meet the Insidious Players: Review of Viral Infections in Head and Neck Cancer Etiology with an Update on Clinical Trials. Microorganisms 9:5, pages 1001.
Crossref
Borislav A. Alexiev, Farres Obeidin, Daniel N. Johnson, Brian S. Finkelman, Rebecca Prince, Shaan N. Somani, Esther Cheng & Sandeep Samant. (2020) Oropharyngeal carcinoma: A single institution study of 338 primaries with special reference to high-risk human papillomavirus-mediated carcinoma with aggressive behavior. Pathology - Research and Practice 216:12, pages 153243.
Crossref
David Landin, Andreas Ährlund‐Richter, Leila Mirzaie, Michael Mints, Anders Näsman, Aeneas Kolev, Linda Marklund, Tina Dalianis, Eva Munck‐Wikland & Torbjörn Ramqvist. (2020) Immune related proteins and tumor infiltrating CD8 + lymphocytes in hypopharyngeal cancer in relation to human papillomavirus ( HPV ) and clinical outcome . Head & Neck 42:11, pages 3206-3217.
Crossref
Mary E. Northridge, Anjali KumarRaghbir Kaur. (2020) Disparities in Access to Oral Health Care. Annual Review of Public Health 41:1, pages 513-535.
Crossref
Alessandro Villa, Lauren L. Patton, Anna R. Giuliano, Cameron G. Estrich, Sarah C. Pahlke, Kelly K. O’Brien, Ruth D. Lipman & Marcelo W.B. Araujo. (2020) Summary of the evidence on the safety, efficacy, and effectiveness of human papillomavirus vaccines. The Journal of the American Dental Association 151:4, pages 245-254.e24.
Crossref
Antti A. Mäkitie, Alhadi Almangush, Omar Youssef, Markus Metsälä, Suvi Silén, Iain J. Nixon, Missak HaigentzJr.Jr., Juan P. Rodrigo, Nabil F. Saba, Vincent Vander Poorten & Alfio Ferlito. (2019) Exhaled breath analysis in the diagnosis of head and neck cancer. Head & Neck 42:4, pages 787-793.
Crossref
Ryan M. Carey, Karthik Rajasekaran, Tyler Seckar, Xiang Lin, Zhi Wei, Charles C.L. Tong, Viran J. Ranasinghe, Jason G. Newman, Bert W. O'MalleyJr.Jr., Gregory S. Weinstein, Michael D. Feldman & Erle S. Robertson. (2020) The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis. Oncotarget 11:3, pages 282-293.
Crossref
Giuseppe Riva, Matteo Biolatti, Giancarlo Pecorari, Valentina Dell’Oste & Santo Landolfo. (2019) PYHIN Proteins and HPV: Role in the Pathogenesis of Head and Neck Squamous Cell Carcinoma. Microorganisms 8:1, pages 14.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.