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Letter

Is the function of the HBeAg really unknown?

Pages 2187-2191 | Received 21 Mar 2019, Accepted 08 Apr 2019, Published online: 09 May 2019

Keep up to date with the latest research on this topic with citation updates for this article.

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Shao-Juan Wang, Zi-Min Chen, Min Wei, Jia-Qi Liu, Zong-Lin Li, Tian-Shu Shi, Sheng Nian, Rao Fu, Yang-Tao Wu, Ya-Li Zhang, Ying-Bin Wang, Tian-Ying Zhang, Jun Zhang, Jun-Hui Xiong, Shu-Ping Tong, Sheng-Xiang Ge, Quan Yuan & Ning-Shao Xia. (2021) Specific determination of hepatitis B e antigen by antibodies targeting precore unique epitope facilitates clinical diagnosis and drug evaluation against hepatitis B virus infection. Emerging Microbes & Infections 10:1, pages 37-50.
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Articles from other publishers (17)

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Hongxiu Jiang, Chao Chen, Deping Yuan, Xiajun Ye, Yan Chen, Guorong Han, Guanlun Zhou, Yuhao Ju & Minkai Cao. (2023) The relationship of maternal hepatitis B e antigen and response to vaccination of infants born to women with chronic infection. BMC Pregnancy and Childbirth 23:1.
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Kiyasha Padarath, Aurélie Deroubaix & Anna Kramvis. (2023) The Complex Role of HBeAg and Its Precursors in the Pathway to Hepatocellular Carcinoma. Viruses 15:4, pages 857.
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Ferruccio Bonino, Piero Colombatto & Maurizia R. Brunetto. (2022) HBeAg-Negative/Anti-HBe-Positive Chronic Hepatitis B: A 40-Year-Old History. Viruses 14:8, pages 1691.
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Xupeng Hong, Stephan Menne & Jianming Hu. (2022) Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/core genes. PLOS Pathogens 18:7, pages e1010739.
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Kuen-Nan Tsai & Jing-Hsiung James Ou. (2021) Hepatitis B virus e antigen and viral persistence. Current Opinion in Virology 51, pages 158-163.
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María Mercedes Elizalde, Luciana Tadey, Lilia Mammana, Jorge Fabián Quarleri, Rodolfo Héctor Campos & Diego Martín Flichman. (2021) Biological Characterization of Hepatitis B virus Genotypes: Their Role in Viral Replication and Antigen Expression. Frontiers in Microbiology 12.
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Matthias Niklasch, Peter Zimmermann & Michael Nassal. (2021) The Hepatitis B Virus Nucleocapsid—Dynamic Compartment for Infectious Virus Production and New Antiviral Target. Biomedicines 9:11, pages 1577.
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Lorenzo Piermatteo, Mohammad Alkhatib, Stefano D’Anna, Vincenzo Malagnino, Ada Bertoli, Eleonora Andreassi, Elisa Basile, Alessandra Iuvara, Maria De Cristofaro, Giuseppina Cappiello, Carlotta Cerva, Carmine Minichini, Mariantonietta Pisaturo, Mario Starace, Nicola Coppola, Carla Fontana, Sandro Grelli, Francesca Ceccherini-Silberstein, Massimo Andreoni, Upkar S. Gill, Patrick T. F. Kennedy, Loredana Sarmati, Romina Salpini & Valentina Svicher. (2021) HBeAg Levels Vary across the Different Stages of HBV Infection According to the Extent of Immunological Pressure and Are Associated with Therapeutic Outcome in the Setting of Immunosuppression-Driven HBV Reactivation. Biomedicines 9:10, pages 1352.
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Pietro Torre, Andrea Aglitti, Mario Masarone & Marcello Persico. (2021) Viral hepatitis: Milestones, unresolved issues, and future goals. World Journal of Gastroenterology 27:28, pages 4603-4638.
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Stewart L. Cooper, Wendy C. King, Douglas B. Mogul, Marc G. Ghany & Kathleen B. Schwarz. (2021) Clinical significance of quantitative e antigen in a cohort of hepatitis B virus‐infected children and adults in North America. Journal of Viral Hepatitis 28:7, pages 1042-1056.
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Yan Xue, Meng Zhang, Tao Li, Feng Liu, Li-Xin Zhang, Xiao-Ping Fan, Bao-Hua Yang & Lei Wang. (2021) Exploration of nucleos(t)ide analogs cessation in chronic hepatitis B patients with hepatitis B e antigen loss. World Journal of Gastroenterology 27:14, pages 1497-1506.
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Aurélie Deroubaix & Anna Kramvis. (2021) In vitro expression of precore proteins of hepatitis B virus subgenotype A1 is affected by HBcAg, and can affect HBsAg secretion. Scientific Reports 11:1.
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Ling Li, Yongan Ye, Yun Ran, Shuyan Liu, Qiyuan Tang, Yaya Liu, Xuejiao Liao, Juanjuan Zhang, Guohui Xiao, Jian Lu, Guoliang Zhang, Qing He & Shiping Hu. (2021) A non-invasive model for predicting liver fibrosis in HBeAg-positive patients with normal or slightly elevated alanine aminotransferase. Medicine 100:17, pages e25581.
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Usha Viswanathan, Nagraj Mani, Zhanying Hu, Haiqun Ban, Yanming Du, Jin Hu, Jinhong Chang & Ju-Tao Guo. (2020) Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B. Antiviral Research 182, pages 104917.
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Meiting Huang, Yunfei Gao, Dandan Liao, Jinna Li, Bo Tang, Yanchen Ma, Xueru Yin, Yongyin Li & Zhihua Liu. (2020) Effects of intrauterine exposure to maternal‐derived HBeAg on T cell immunity in cord blood. Scandinavian Journal of Immunology 92:2.
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Wolfram H. Gerlich, Dieter Glebe, Anna Kramvis & Lars O. Magnius. (2020) Peculiarities in the designations of hepatitis B virus genes, their products, and their antigenic specificities: a potential source of misunderstandings. Virus Genes 56:2, pages 109-119.
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