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Human Vaccines & Immunotherapeutics Volume 17, 2021 - Issue 7
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Research Article

Formulation development of a live attenuated human rotavirus (RV3-BB) vaccine candidate for use in low- and middle-income countries

Prashant Kumara Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USAView further author information
,
Ravi S. Shuklaa Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USAView further author information
,
Ashaben Patela Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USAView further author information
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Swathi R. Pullagurlaa Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USAView further author information
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Christopher Birda Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USAView further author information
,
Oluwadara Oguna Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USAView further author information
,
Ozan S. Kumrua Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USAView further author information
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Ahd Hamidib Batavia Biosciences B.V., Bioscience Park Leiden, Leiden, The NetherlandsView further author information
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Femke Hoeksemab Batavia Biosciences B.V., Bioscience Park Leiden, Leiden, The NetherlandsView further author information
,
Christopher Yallopb Batavia Biosciences B.V., Bioscience Park Leiden, Leiden, The NetherlandsView further author information
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Julie E. Binesc Murdoch Children’s Research Institute, Department of Paediatrics, University of Melbourne, Parkville, Australia;d Department of Gastroenterology and Clinical Nutrition, Royal Children’s Hospital, Parkville, AustraliaView further author information
,
Sangeeta B. Joshia Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USACorrespondence[email protected]
View further author information
&
David B. Volkina Department of Pharmaceutical Chemistry, Vaccine Analytics and Formulation Center, University of Kansas, Lawrence, KS, USACorrespondence[email protected]
View further author information
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Pages 2298-2310 | Received 01 Oct 2020, Accepted 29 Jan 2021, Published online: 16 Apr 2021

Citations (8)

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Read on this site (2)

Prashant Kumar & Vibhuti Agrahari. (2023) Analytical Considerations to Support Expeditious Formulation Development of Vaccines. Bioanalysis 15:12, pages 653-655.
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Prashant Kumar, Christopher Bird, David Holland, Sangeeta B. Joshi & David B. Volkin. (2022) Current and next-generation formulation strategies for inactivated polio vaccines to lower costs, increase coverage, and facilitate polio eradication. Human Vaccines & Immunotherapeutics 18:7.
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Articles from other publishers (6)

Prashant Kumar, Michael Wang, Ozan S. Kumru, John M. Hickey, Julio Sanmiguel, Nerea Zabaleta, Luk H. Vandenberghe, Sangeeta B. Joshi & David B. Volkin. (2023) Correlating physicochemical and biological properties to define critical quality attributes of a rAAV vaccine candidate. Molecular Therapy - Methods & Clinical Development 30, pages 103-121.
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Sakshi Bajoria, Lorena R. Antunez, Ozan S. Kumru, Mark Klempner, Yang Wang, Lisa A. Cavacini, Sangeeta B. Joshi & David B. Volkin. (2023) Formulation Studies to Develop Low-Cost, Orally-Delivered Secretory IgA Monoclonal Antibodies for Passive Immunization Against Enterotoxigenic Escherichia coli. Journal of Pharmaceutical Sciences 112:7, pages 1832-1844.
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Tatsuya Kato, Tatsuki Kakuta, Ami Yonezuka, Tomofumi Sekiguchi, Yuki Machida, Jian Xu, Tohru Suzuki & Enoch Y. Park. (2022) Expression and Purification of Porcine Rotavirus Structural Proteins in Silkworm Larvae as a Vaccine Candidate. Molecular Biotechnology 65:3, pages 401-409.
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Ulrich Desselberger. (2023) 14th International dsRNA Virus Symposium, Banff, Alberta, Canada, 10-14 October 2022. Virus Research 324, pages 199032.
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Swathi R. Pullagurla, Prashant Kumar, Oluwadara Ogun, Ozan S. Kumru, Ahd Hamidi, Femke Hoeksema, Christopher Yallop, Julie E. Bines, David B. Volkin & Sangeeta B. Joshi. (2022) Modeling the long-term 2-8 °C stability profiles of a live, rotavirus vaccine candidate (RV3-BB) in various liquid formulations via extrapolations of real-time and accelerated stability data. Biologicals 75, pages 21-28.
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Ahd Hamidi, Femke Hoeksema, Pim Velthof, Angelique Lemckert, Gert Gillissen, Alfred Luitjens, Julie E. Bines, Swathi R. Pullagurla, Prashant Kumar, David B. Volkin, Sangeeta B. Joshi, Menzo Havenga, Wilfried A.M. Bakker & Christopher Yallop. (2021) Developing a manufacturing process to deliver a cost effective and stable liquid human rotavirus vaccine. Vaccine 39:15, pages 2048-2059.
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