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Bioengineered Volume 6, 2015 - Issue 5
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Addenda

Antibody proteolysis: a common picture emerging from plants

Marcello DoniniLaboratory of Biotechnology; ENEA Research Center Casaccia; Rome, ItalyCorrespondence[email protected]
,
Raffaele LombardiLaboratory of Biotechnology; ENEA Research Center Casaccia; Rome, Italy
,
Chiara LonoceLaboratory of Biotechnology; ENEA Research Center Casaccia; Rome, Italy
,
Mariasole Di CarliLaboratory of Biotechnology; ENEA Research Center Casaccia; Rome, Italy
,
Carla MarusicLaboratory of Biotechnology; ENEA Research Center Casaccia; Rome, Italy
,
Veronica MoreaNational Research Council; Institute of Molecular Biology and Pathology; Rome, Italy
&
Patrizio Di MiccoDepartment of Radiology, Oncology and Pathology; Sapienza University of Rome; Rome, Italy
 show all
Pages 299-302 | Received 13 May 2015, Accepted 24 Jun 2015, Published online: 25 Jul 2015

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Matthias Knödler, Katharina Frank, Lucy Kerpen & Johannes Felix Buyel. (2023) Design, optimization, production and activity testing of recombinant immunotoxins expressed in plants and plant cells for the treatment of monocytic leukemia. Bioengineered 14:1.
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Priyen Pillay, Karl J. Kunert, Stefan van Wyk, Matome Eugene Makgopa, Christopher A. Cullis & Barend J. Vorster. (2016) Agroinfiltration contributes to VP1 recombinant protein degradation. Bioengineered 7:6, pages 459-477.
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Pragya Tiwari, Yashdeep Srivastava, Abhishek Sharma & Ramachandran Vinayagam. (2023) Antimicrobial Peptides: The Production of Novel Peptide-Based Therapeutics in Plant Systems. Life 13:9, pages 1875.
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J. F. Buyel. (2023) Product safety aspects of plant molecular farming. Frontiers in Bioengineering and Biotechnology 11.
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M. M. Aragão, M. A. Alvarez, L. Caiafa & M. O. Santos. (2023) Nicotiana hairy roots for recombinant protein expression, where to start? A systematic review. Molecular Biology Reports 50:5, pages 4587-4604.
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Rachele Frigerio, Carla Marusic, Maria Elena Villani, Chiara Lico, Cristina Capodicasa, Emanuele Andreano, Ida Paciello, Rino Rappuoli, Anna Maria Salzano, Andrea Scaloni, Selene Baschieri & Marcello Donini. (2022) Production of two SARS-CoV-2 neutralizing antibodies with different potencies in Nicotiana benthamiana. Frontiers in Plant Science 13.
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Pragya Tiwari, Yashdeep Srivastava & Vinay Kumar. 2022. Antimicrobial Resistance. Antimicrobial Resistance 289 322 .
J. F. Buyel, E. Stöger & L. Bortesi. (2021) Targeted genome editing of plants and plant cells for biomanufacturing. Transgenic Research 30:4, pages 401-426.
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Emile Rage, Carla Marusic, Chiara Lico, Anna Maria Salzano, Andrea Scaloni, Selene Baschieri & Marcello Donini. (2020) Optimisation of PD-FcY veterinary antigen secretion from Nicotiana benthamiana hairy roots and purification from the culture medium. Plant Cell, Tissue and Organ Culture (PCTOC) 142:1, pages 23-39.
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Nazrin Abd-Aziz, Boon Chin Tan, Nur Ardiyana Rejab, Rofina Yasmin Othman & Norzulaani Khalid. (2020) A New Plant Expression System for Producing Pharmaceutical Proteins. Molecular Biotechnology 62:4, pages 240-251.
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Chiara Lonoce, Carla Marusic, Elena Morrocchi, Anna Maria Salzano, Andrea Scaloni, Flavia Novelli, Claudio Pioli, Mistianne Feeney, Lorenzo Frigerio & Marcello Donini. (2019) Enhancing the Secretion of a Glyco-Engineered Anti-CD20 scFv-Fc Antibody in Hairy Root Cultures. Biotechnology Journal 14:3, pages 1800081.
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Friederike Grosse-Holz, Luisa Madeira, Muhammad Awais Zahid, Molly Songer, Jiorgos Kourelis, Mary Fesenko, Sabrina Ninck, Farnusch Kaschani, Markus Kaiser & Renier A.L. van der Hoorn. (2018) Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana . Plant Biotechnology Journal 16:10, pages 1797-1810.
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Philippe V. Jutras, Carla Marusic, Chiara Lonoce, Carole Deflers, Marie-Claire Goulet, Eugenio Benvenuto, Dominique Michaud & Marcello Donini. (2016) An Accessory Protease Inhibitor to Increase the Yield and Quality of a Tumour-Targeting mAb in Nicotiana benthamiana Leaves. PLOS ONE 11:11, pages e0167086.
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Chiara Lonoce, Reda Salem, Carla Marusic, Philippe V. Jutras, Andrea Scaloni, Anna Maria Salzano, Sergio Lucretti, Herta Steinkellner, Eugenio Benvenuto & Marcello Donini. (2016) Production of a tumour-targeting antibody with a human-compatible glycosylation profile in N. benthamiana hairy root cultures . Biotechnology Journal 11:9, pages 1209-1220.
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Melanie Paireder, Ulrich Mehofer, Stefan Tholen, Andreas Porodko, Philipp Schähs, Daniel Maresch, Martin L. Biniossek, Renier A.L. van der Hoorn, Brigita Lenarcic, Marko Novinec, Oliver Schilling & Lukas Mach. (2016) The death enzyme CP14 is a unique papain-like cysteine proteinase with a pronounced S2 subsite selectivity. Archives of Biochemistry and Biophysics 603, pages 110-117.
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Manoj K. Mandal, Houtan Ahvari, Stefan Schillberg & Andreas Schiermeyer. (2016) Tackling Unwanted Proteolysis in Plant Production Hosts Used for Molecular Farming. Frontiers in Plant Science 7.
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