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Bioengineered Volume 12, 2021 - Issue 1
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Research Paper

Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin

Yan Wanga Department of Pathology, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, the First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, ChinaView further author information
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Zhiqiang Chenga Department of Pathology, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, the First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, ChinaView further author information
,
Jing Xua Department of Pathology, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, the First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, ChinaView further author information
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Meina Laia Department of Pathology, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, the First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, ChinaView further author information
,
Liming Liua Department of Pathology, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, the First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, ChinaView further author information
,
Min Zuoa Department of Pathology, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, the First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, ChinaCorrespondence[email protected]
View further author information
&
Lin Dangb Department of Dermatology, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, the First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, ChinaCorrespondence[email protected]
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Pages 1874-1889 | Received 02 Feb 2021, Accepted 27 Apr 2021, Published online: 02 Jun 2021

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Sébastien Relier, Eric Rivals & Alexandre David. (2022) The multifaceted functions of the Fat mass and Obesity-associated protein (FTO) in normal and cancer cells. RNA Biology 19:1, pages 132-142.
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XiaoJing Chen, Yite Xue, Lingfang Wang, Yang Weng, Sen Li, Weiguo Lü, Xing Xie & Xiaodong Cheng. (2022) Lectin galactoside-binding soluble 3 binding protein mediates methotrexate resistance in choriocarcinoma cell lines. Bioengineered 13:2, pages 2076-2086.
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Feng Xiao & Jianrong Zhou. (2021) RETRACTED ARTICLE: FTO Gene Polymorphisms Contribute to the Predisposition and Radiotherapy Efficiency of Nasopharyngeal Carcinoma. Pharmacogenomics and Personalized Medicine 14, pages 1239-1245.
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XiangRong Luo, JianTao She, Tao Xu, Yuan Zhou, ChuanBo Xu, JianPing Jiang, TianGang Li, Huajiang Liu, Hui Shen, Bolong Yin & Bin Dai. (2021) Establishment and characterization of organoids from a patient with adenomyoepithelioma of the breast. Bioengineered 12:2, pages 11578-11585.
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Articles from other publishers (11)

Xue Chen, Ying Wang, Jia-Nan Wang, Yi-Chen Zhang, Ye-Ran Zhang, Ru-Xu Sun, Bing Qin, Yuan-Xin Dai, Hong-Jing Zhu, Jin-Xiang Zhao, Wei-Wei Zhang, Jiang-Dong Ji, Song-Tao Yuan, Qun-Dong Shen & Qing-Huai Liu. (2024) Lactylation-driven FTO targets CDK2 to aggravate microvascular anomalies in diabetic retinopathy. EMBO Molecular Medicine 16:2, pages 294-318.
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Chendong Fu, Xianting Li, Lang Han, Ming Xie & Shurui Ouyang. (2022) LncRNA PTPRG-AS1 maintains stem-cell-like features and promotes oxaliplatin resistance in colorectal cancer via regulating the miR-665 and STAT3 axis. Molecular & Cellular Toxicology 20:1, pages 35-45.
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Kai Lin, Endi Zhou, Ting Shi, Siqing Zhang, Jinfan Zhang, Ziruo Zheng, Yuetian Pan, Wentao Gao & Yabin Yu. (2023) m6A eraser FTO impairs gemcitabine resistance in pancreatic cancer through influencing NEDD4 mRNA stability by regulating the PTEN/PI3K/AKT pathway. Journal of Experimental & Clinical Cancer Research 42:1.
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Hengzhao Zhuang, Bo Yu, Dan Tao, Xiaoyan Xu, Yijun Xu, Jian Wang, Yang Jiao & Lili Wang. (2023) The role of m6A methylation in therapy resistance in cancer. Molecular Cancer 22:1.
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Wei-Wei Liu, Zhong-Yuan Zhang, Fei Wang & Hao Wang. (2023) Emerging roles of m6A RNA modification in cancer therapeutic resistance. Experimental Hematology & Oncology 12:1.
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Yuanliang Yan, Jinwu Peng, Qiuju Liang, Xinxin Ren, Yuan Cai, Bi Peng, Xi Chen, Xiang Wang, Qiaoli Yi & Zhijie Xu. (2023) Dynamic m6A-ncRNAs association and their impact on cancer pathogenesis, immune regulation and therapeutic response. Genes & Diseases 10:1, pages 135-150.
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Zaoqu Liu, Haijiao Zou, Qin Dang, Hui Xu, Long Liu, Yuyuan Zhang, Jinxiang Lv, Huanyun Li, Zhaokai Zhou & Xinwei Han. (2022) Biological and pharmacological roles of m6A modifications in cancer drug resistance. Molecular Cancer 21:1.
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Zhen Fang, Wentong Mei, Chang Qu, Jiongdi Lu, Liang Shang, Feng Cao & Fei Li. (2022) Role of m6A writers, erasers and readers in cancer. Experimental Hematology & Oncology 11:1.
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Yangchan Li, Rui Su, Xiaolan Deng, Yong Chen & Jianjun Chen. (2022) FTO in cancer: functions, molecular mechanisms, and therapeutic implications. Trends in Cancer 8:7, pages 598-614.
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Lin Yao, Chang-Feng Man, Rong He, Lian He, Jia-Bin Huang, Shou-Yan Xiang, Zhe Dai, Xiao-Yan Wang & Yu Fan. (2022) The Interaction Between N6-Methyladenosine Modification and Non-Coding RNAs in Gastrointestinal Tract Cancers. Frontiers in Oncology 11.
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Na Li, Xiaojuan Chen, Yanhong Liu, Tieming Zhou & Wei Li. (2021) Gene Characteristics and Prognostic Values of m6A RNA Methylation Regulators in Nonsmall Cell Lung Cancer. Journal of Healthcare Engineering 2021, pages 1-12.
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