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Bioengineered Volume 12, 2021 - Issue 1
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Tripterygium glycoside ameliorates neuroinflammation in a mouse model of Aβ25-35-induced Alzheimer’s disease by inhibiting the phosphorylation of IκBα and p38

Liang Tanga Department of Basic Biology, Changsha Medical College, Changsha, China;b Department of Basic Biology, Wuzhou Medical College, Wuzhou, China;c Center for Neuroscience and Behavior, Changsha Medical College, Changsha, China;d Academics Working Station, Changsha Medical College, Changsha, ChinaView further author information
,
Qin Xianga Department of Basic Biology, Changsha Medical College, Changsha, China;c Center for Neuroscience and Behavior, Changsha Medical College, Changsha, ChinaView further author information
,
Ju Xianga Department of Basic Biology, Changsha Medical College, Changsha, China;c Center for Neuroscience and Behavior, Changsha Medical College, Changsha, ChinaView further author information
,
Yan Zhangd Academics Working Station, Changsha Medical College, Changsha, China;e School of Computer Science and Engineering, Central South University, Changsha, ChinaView further author information
&
Jianming Lia Department of Basic Biology, Changsha Medical College, Changsha, China;c Center for Neuroscience and Behavior, Changsha Medical College, Changsha, China;d Academics Working Station, Changsha Medical College, Changsha, China;f Department of Rehabilitation, Xiangya Boai Rehabilitation Hospital, Changsha, ChinaCorrespondence[email protected]
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Pages 8540-8554 | Received 12 Aug 2021, Accepted 24 Sep 2021, Published online: 19 Oct 2021

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Mingqin Lin, Peiqiong Li, Wei Liu, Tianqi Niu & Liping Huang. (2022) Germacrone alleviates okadaic acid-induced neurotoxicity in PC12 cells via M1 muscarinic receptor-mediated Galphaq (Gq)/phospholipase C beta (PLCβ)/ protein kinase C (PKC) signaling. Bioengineered 13:3, pages 4898-4910.
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Wenjun Wan, Ganzhe Liu, Xia Li, Yu Liu, Ying Wang, Haisong Pan & Jun Hu. (2021) MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer’s disease. Bioengineered 12:2, pages 12678-12690.
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Yongcang Zhang, Liang Tang, Yan Wang, Xiaoyan Zhu & Lan Liu. (2024) In-depth analyses of lncRNA and circRNA expression in the hippocampus of LPS-induced AD mice by Byu d Mar 25. NeuroReport 35:1, pages 49-60.
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Yujia Zheng, Xiaolu Zhang, Ruifeng Zhang, Ziyu Wang, Jiali Gan, Qing Gao, Lin Yang, Pengjuan Xu & Xijuan Jiang. (2023) Inflammatory signaling pathways in the treatment of Alzheimer's disease with inhibitors, natural products and metabolites (Review). International Journal of Molecular Medicine 52:5.
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Liang Tang, Yan Wang, Xujing Gong, Ju Xiang, Yan Zhang, Qin Xiang & Jianming Li. (2023) Integrated transcriptome and metabolome analysis to investigate the mechanism of intranasal insulin treatment in a rat model of vascular dementia. Frontiers in Pharmacology 14.
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Guohui Xue, Huifang Xiong, Shixiu Wang, Yingjun Fu & Yong Xie. (2023) Eudragit-coated chitosan-tripterygium glycoside conjugate microspheres alleviate DSS-induced experimental colitis by inhibiting the TLR4/NF-κB signaling pathway. Biomedicine & Pharmacotherapy 158, pages 114194.
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Chengzhao Li, Jun Dang, Yue Lv, Yan Fang, Chengjun Ma, Qilan Wang & Gang Li. (2022) The Isolation and Preparation of Samwinol from Dracocephalum heterophyllum and Prevention on Aβ25–35-Induced Neuroinflammation in PC-12 Cells. International Journal of Molecular Sciences 23:19, pages 11572.
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Yuanqiang Zhang, Dongqing Liu, Xutao Yao, Jing Wen, Yuhang Wang & Yubin Zhang. (2022) DMTHB ameliorates memory impairment in Alzheimer's disease mice through regulation of neuroinflammation. Neuroscience Letters 785, pages 136770.
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Chenling Zhao, Zhangsheng Jiang, Liwei Tian, Lulu Tang, An Zhou & Ting Dong. (2022) Bioinformatics-Based Approach for Exploring the Immune Cell Infiltration Patterns in Alzheimer’s Disease and Determining the Intervention Mechanism of Liuwei Dihuang Pill. Dose-Response 20:3, pages 155932582211155.
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