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Bioengineered Volume 13, 2022 - Issue 3
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Research Paper

Synergistic anticancer effects of everolimus (RAD001) and Rhein on gastric cancer cells via phosphoinositide-3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway

Feng Gaoa Teaching and Research Office of Chinese Pharmacy, The College of Pharmacy of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaView further author information
,
Rui Lib Department of Emergency, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaView further author information
,
Pei-Feng Weic The Office of Drug Clinical Trial Institution, The Second Affiliated Hospital of Shaanxi University of traditional Chinese Medicine, Xianyang, Shaanxi, ChinaView further author information
,
Li Oua Teaching and Research Office of Chinese Pharmacy, The College of Pharmacy of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaView further author information
,
Min Lia Teaching and Research Office of Chinese Pharmacy, The College of Pharmacy of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaView further author information
,
Yang Baic The Office of Drug Clinical Trial Institution, The Second Affiliated Hospital of Shaanxi University of traditional Chinese Medicine, Xianyang, Shaanxi, ChinaView further author information
,
Wen-Jia Luoa Teaching and Research Office of Chinese Pharmacy, The College of Pharmacy of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaView further author information
&
Zhen Fand Department of Gastroenterology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang712000, Shaanxi, ChinaCorrespondence[email protected]
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Pages 6332-6342 | Received 01 Sep 2021, Accepted 09 Nov 2021, Published online: 28 Feb 2022

Citations (4)

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Lili Song, Shikai Liu & Sufen Zhao. (2022) Everolimus (RAD001) combined with programmed death-1 (PD-1) blockade enhances radiosensitivity of cervical cancer and programmed death-ligand 1 (PD-L1) expression by blocking the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR)/S6 kinase 1 (S6K1) pathway. Bioengineered 13:4, pages 11240-11257.
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Articles from other publishers (3)

Yue Hu, Lin Yang & Yu Lai. (2023) Recent findings regarding the synergistic effects of emodin and its analogs with other bioactive compounds: Insights into new mechanisms. Biomedicine & Pharmacotherapy 162, pages 114585.
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Md. Ataur Rahman, Kazi Rejvee Ahmed, Farzana Haque, Moon Nyeo Park & Bonglee Kim. (2023) Recent Advances in Cellular Signaling Interplay between Redox Metabolism and Autophagy Modulation in Cancer: An Overview of Molecular Mechanisms and Therapeutic Interventions. Antioxidants 12:2, pages 428.
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Chuanshan Yao & Feng Wang. (2022) Inhibition of hypoxia‐induced HIF‐1α‐mediated autophagy enhances the in vitro antitumor activity of rhein in pancreatic cancer cells. Journal of Applied Toxicology 42:12, pages 1937-1947.
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