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Bioengineered Volume 13, 2022 - Issue 4
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Research Paper

Astragaloside-IV alleviates high glucose-induced ferroptosis in retinal pigment epithelial cells by disrupting the expression of miR-138-5p/Sirt1/Nrf2

Xuyuan Tanga Department of Ophthalmology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, ChinaView further author information
,
Xiuyi Lia Department of Ophthalmology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, ChinaView further author information
,
Dongyan Zhanga Department of Ophthalmology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, ChinaView further author information
&
Wei Hanb Department of Ophthalmology, Eye Center of the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaCorrespondence[email protected]
View further author information
Pages 8238-8253 | Received 16 Dec 2021, Accepted 28 Feb 2022, Published online: 18 Mar 2022

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Dandan Xie, Kai Li, Ruxue Feng, Man Xiao, Zhifeng Sheng & Yiqiang Xie. (2023) Ferroptosis and Traditional Chinese Medicine for Type 2 Diabetes Mellitus. Diabetes, Metabolic Syndrome and Obesity 16, pages 1915-1930.
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Articles from other publishers (17)

Ying Liu, Wei Ding, Jianxun Wang, Xiang Ao & Junqiang Xue. (2023) Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases. Biomedicine & Pharmacotherapy 164, pages 114993.
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Jing Ma, Ting Chen & Ranran Wang. (2023) Astragaloside IV ameliorates cognitive impairment and protects oligodendrocytes from antioxidative stress via regulation of the SIRT1/Nrf2 signaling pathway. Neurochemistry International 167, pages 105535.
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Dan Cao, Cong Wang & Liang Zhou. (2023) Identification and comprehensive analysis of ferroptosis-related genes as potential biomarkers for the diagnosis and treatment of proliferative diabetic retinopathy by bioinformatics methods. Experimental Eye Research 232, pages 109513.
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Yung Hyun Choi. (2023) Reduction of high glucose-induced oxidative injury in human retinal pigment epithelial cells by sarsasapogenin through inhibition of ROS generation and inactivation of NF-κB/NLRP3 inflammasome pathway. Genes & Genomics.
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Wei He, Lu Chang, Xinlu Li & Yan Mei. (2023) Research progress on the mechanism of ferroptosis and its role in diabetic retinopathy. Frontiers in Endocrinology 14.
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Jialing Zhang, Ting Zhang, Shaoxue Zeng, Xinyuan Zhang, Fanfan Zhou, Mark C. Gillies & Ling Zhu. (2023) The Role of Nrf2/sMAF Signalling in Retina Ageing and Retinal Diseases. Biomedicines 11:6, pages 1512.
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Jianrui Zhang, Si-an Xie, Jin Wang, Jiayu Liu, Yueqi Liu, Shuang Zhou, Xixi Li, Lili Han, Wei Pang, Weijuan Yao, Yi Fu, Wei Kong, Min Ye & Jing Zhou. (2023) Echinatin maintains glutathione homeostasis in vascular smooth muscle cells to protect against matrix remodeling and arterial stiffening. Matrix Biology 119, pages 1-18.
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Jieqing Zeng, Junhao Guo, Si Huang, Yisen Cheng, Fei Luo, Xusan Xu, Riling Chen, Guoda Ma & Yajun Wang. (2023) The roles of sirtuins in ferroptosis. Frontiers in Physiology 14.
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Lele Wang, Canwen Liu, Linlin Wang & Biao Tang. (2023) Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis. European Journal of Pharmacology 944, pages 175516.
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Oke-Oghene Philomena Akpoveso, Emeka Emmanuel Ubah & Gideon Obasanmi. (2023) Antioxidant Phytochemicals as Potential Therapy for Diabetic Complications. Antioxidants 12:1, pages 123.
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Xia Wu, Shangqing Chen, Kechu Huang & Gongping Lin. (2022) Triptolide promotes ferroptosis by suppressing Nrf2 to overcome leukemia cell resistance to doxorubicin. Molecular Medicine Reports 27:1.
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Jingying Liu, Xiaozhuang Li, Yanhua Cheng, Kangcheng Liu, Hua Zou & Zhipeng You. (2022) Identification of potential ferroptosis-related biomarkers and a pharmacological compound in diabetic retinopathy based on machine learning and molecular docking. Frontiers in Endocrinology 13.
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Bo-Yie Chen, Jyh-Cheng Liou, Jia-Lain Wu, Chao-Hsiang Chen & Shih-Liang Yang. (2022) Photoreceptor and vision protective effects of astragaloside IV in mice model with light-evoked retinal damage. Biomedicine & Pharmacotherapy 153, pages 113404.
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Yao Tong, Zunyi Zhang & Shusheng Wang. (2022) Role of Mitochondria in Retinal Pigment Epithelial Aging and Degeneration. Frontiers in Aging 3.
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Sheng Gao, Yun Zhang & Meixia Zhang. (2022) Targeting Novel Regulated Cell Death: Pyroptosis, Necroptosis, and Ferroptosis in Diabetic Retinopathy. Frontiers in Cell and Developmental Biology 10.
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Zhi-Hao Zhao, Min Xu, Cong Fu, Ying Huang, Ting-Hua Wang, Zhong-Fu Zuo & Xue-Zheng Liu. (2022) A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology. Frontiers in Pharmacology 13.
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Keiko Hosohata, Tanisorn Harnsirikarn & Susama Chokesuwattanaskul. (2022) Ferroptosis: A Potential Therapeutic Target in Acute Kidney Injury. International Journal of Molecular Sciences 23:12, pages 6583.
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