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Rare Diseases Volume 4, 2016 - Issue 1

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Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation

Kerri J. KinghornInstitute of Healthy Ageing and Department of Genetics, Environment and Evolution, University College London, London, UK;Institute of Neurology, University College London, Queen Square, London, UKCorrespondence[email protected]

Jorge Iván Castillo-QuanInstitute of Healthy Ageing and Department of Genetics, Environment and Evolution, University College London, London, UK;Institute of Neurology, University College London, Queen Square, London, UK

Article: e1128616 | Received 13 Jul 2015, Accepted 01 Dec 2015, Published online: 18 Feb 2016

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https://doi.org/10.1080/21675511.2015.1128616
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Marta Talaverón-Rey, Mónica Álvarez-Córdoba, Irene Villalón-García, Suleva Povea-Cabello, Juan M. Suárez-Rivero, David Gómez-Fernández, Ana Romero-González, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Paula Cilleros-Holgado, Diana Reche-López, Rocío Piñero-Pérez & José A. Sánchez-Alcázar. (2023) Alpha-lipoic acid supplementation corrects pathological alterations in cellular models of pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels. Orphanet Journal of Rare Diseases 18:1.
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Shivangi Puri, Ritesh K. Agrawal, Ankur Singh, Ashish Verma, Arpita Mishra, Ashok Singh, Raghvendra Narayan & Om P. Mishra. (2022) Spectrum of Neurodegeneration with Brain Iron Accumulation with PLA2G6 Variation: A Report of Three Cases from Two Families. Journal of Pediatric Neurology 21:02, pages 122-127.
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Irene Villalón-García, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Marta Talaverón-Rey, JuanM Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez & JoséA Sánchez-Alcázar. (2023) Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration. Neural Regeneration Research 18:6, pages 1196.
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Petr Dusek, Tim Hofer, Jan Alexander, Per M. Roos & Jan O. Aaseth. (2022) Cerebral Iron Deposition in Neurodegeneration. Biomolecules 12:5, pages 714.
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Indrani Datta, Aishwarya Raj & Alka Kaushal. 2022. The Biology of Glial Cells: Recent Advances. The Biology of Glial Cells: Recent Advances 243 291 .

Vassilena Iankova, Ivan Karin, Thomas Klopstock & Susanne A. Schneider. (2021) Emerging Disease-Modifying Therapies in Neurodegeneration With Brain Iron Accumulation (NBIA) Disorders. Frontiers in Neurology 12.
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Isabel Hinarejos, Candela Machuca, Paula Sancho & Carmen Espinós. (2020) Mitochondrial Dysfunction, Oxidative Stress and Neuroinflammation in Neurodegeneration with Brain Iron Accumulation (NBIA). Antioxidants 9:10, pages 1020.
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Sylvain Ferrandon, Jennifer DeVecchio, Leonardo Duraes, Hanumant Chouhan, Georgios Karagkounis, Jacqueline Davenport, Matthew Orloff, David Liska & Matthew F. Kalady. (2020) CoA Synthase ( COASY ) Mediates Radiation Resistance via PI3K Signaling in Rectal Cancer . Cancer Research 80:2, pages 334-346.
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Rosangela Ferese, Simona Scala, Francesca Biagioni, Emiliano Giardina, Stefania Zampatti, Nicola Modugno, Claudio Colonnese, Marianna Storto, Francesco Fornai, Giuseppe Novelli, Stefano Ruggieri & Stefano Gambardella. (2018) Heterozygous PLA2G6 Mutation Leads to Iron Accumulation Within Basal Ganglia and Parkinson's Disease. Frontiers in Neurology 9.
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Kerri J. Kinghorn, Jorge Iván Castillo-Quan, Li Li, Kailash P. Bhatia, Andrey Y. Abramov, John Hardy & Linda Partridge. (2016) Reply: Glial mitochondropathy in infantile neuroaxonal dystrophy: pathophysiological and therapeutic implications. Brain 139:12, pages e68-e68.
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Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation

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Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation

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