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Rare Diseases Volume 4, 2016 - Issue 1

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Addendum

The conditional KO approach: Cre/Lox technology in human neurons

Christopher PatzkeDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USACorrespondence[email protected]

Thomas C. SüdhofDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA;Howard Hughes Medical Institute, Stanford University School of Medicine; Stanford, CA, USA

Article: e1131884 | Received 01 Oct 2015, Accepted 09 Dec 2015, Published online: 18 Feb 2016

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https://doi.org/10.1080/21675511.2015.1131884
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Articles from other publishers (8)

Cecilia Ortíz, Santiago Ruatta & Marcelo Comini. 2022. Drug Target Selection and Validation. Drug Target Selection and Validation 61 82 .

Christopher Patzke, Jinye Dai, Marisa M. Brockmann, Zijun Sun, Pascal Fenske, Christian Rosenmund & Thomas C. Südhof. (2021) Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating synapsins in human synapses. Molecular Psychiatry 26:11, pages 6253-6268.
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E. A. Cherkashova, G. E. Leonov, D. D. Namestnikova, A. A. Solov’eva, I. L. Gubskii, T. B. Bukharova, L. V. Gubskii, D. V. Goldstein & K. N. Yarygin. (2020) Methods of Generation of Induced Pluripotent Stem Cells and Their Application for the Therapy of Central Nervous System Diseases. Bulletin of Experimental Biology and Medicine 168:4, pages 566-573.
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Wei Niu & Jack M. Parent. (2019) Modeling genetic epilepsies in a dish. Developmental Dynamics 249:1, pages 56-75.
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Thomas C. Südhof. (2018) Towards an Understanding of Synapse Formation. Neuron 100:2, pages 276-293.
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Ruijiao Zhou, Guohui Jiang, Xin Tian & Xuefeng Wang. (2018) Progress in the molecular mechanisms of genetic epilepsies using patient-induced pluripotent stem cells. Epilepsia Open 3:3, pages 331-339.
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Zhenjie Zhang, Samuele G. Marro, Yingsha ZhangKristin L. Arendt, Christopher PatzkeBo ZhouTyler FairNan YangThomas C. Südhof, Marius WernigLu Chen. (2018) The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling. Science Translational Medicine 10:452.
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Jeffrey Noebels. (2017) Precision physiology and rescue of brain ion channel disorders. Journal of General Physiology 149:5, pages 533-546.
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