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Simvastatin offers new prospects for the treatment of Duchenne muscular dystrophy

Nicholas P. WhiteheadDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, USACorrespondence[email protected]

Min Jeong KimDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, USA

Kenneth L. BibleDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, USA

Marvin E. AdamsDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, USA

Stanley C. FroehnerDepartment of Physiology and Biophysics, University of Washington, Seattle, WA, USA

Article: e1156286 | Received 11 Nov 2015, Accepted 12 Feb 2016, Published online: 12 Apr 2016

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https://doi.org/10.1080/21675511.2016.1156286
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Abdolvahab Ebrahimpour Gorji, Piotr Ostaszewski, Kaja Urbańska & Tomasz Sadkowski. (2023) Does β-Hydroxy-β-Methylbutyrate Have Any Potential to Support the Treatment of Duchenne Muscular Dystrophy in Humans and Animals?. Biomedicines 11:8, pages 2329.
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Ingrid E.C. Verhaart, Ornella Cappellari, Christa L. Tanganyika-de Winter, Jaap J. Plomp, Sofia Nnorom, Kim E. Wells, John C.W. Hildyard, David Bull, Annemieke Aartsma-Rus & Dominic J. Wells. (2021) Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy. Journal of Neuromuscular Diseases 8:5, pages 845-863.
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Dengqiu Xu, Lei Zhao, Jingwei Jiang, Sijia Li, Zeren Sun, Xiaofei Huang, Chunjie Li, Tao Wang, Lixin Sun, Xihua Li, Zhenzhou Jiang & Luyong Zhang. (2020) A potential therapeutic effect of catalpol in Duchenne muscular dystrophy revealed by binding with TAK1. Journal of Cachexia, Sarcopenia and Muscle 11:5, pages 1306-1320.
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Júlia M.G. Finkler, Samara C. de Carvalho, Humberto Santo Neto & Maria J. Marques. (2019) Cardiac and skeletal muscle changes associated with rosuvastatin therapy in dystrophic mdx mice . The Anatomical Record 303:8, pages 2202-2212.
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Christine Péladeau, Nadine Adam, Lucas M. Bronicki, Adèle Coriati, Mohamed Thabet, Hasanen Al-Rewashdy, Jason Vanstone, Alan Mears, Jean-Marc Renaud, Martin Holcik & Bernard J. Jasmin. (2020) Identification of therapeutics that target eEF1A2 and upregulate utrophin A translation in dystrophic muscles. Nature Communications 11:1.
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Mackenzie Hagan, Muhammad Ashraf, Il-man Kim, Neal L. Weintraub & Yaoliang Tang. (2018) Effective regeneration of dystrophic muscle using autologous iPSC-derived progenitors with CRISPR-Cas9 mediated precise correction. Medical Hypotheses 110, pages 97-100.
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E.P. Hoffman, Carsten Bonnemann, Marc Boutin, Bernard Brais, Filippo Buccella, Arthur Burghes, Christopher Coffey, Nabarun Dasgupta, Hugh Dawkins, Annamaria De Luca, Christopher Dowd, Tina Duong, Michelle Eagle, Richard Finkel, Pat Furlong, Cynthia Gagnon, Nathalie Goemans, Michela Guglieri, Yetrib Hathout, Nicholas Johnson, Emil Kakkis, Petra Kaufmann, Jonathan Kimmelman, Lawrence Korngut, Joyce Kullman, Hanns Lochmüller, Stefano Marini, Craig McDonald, Charles Mohan, Lauren Morgenroth, Hiroki Morizono, Kanneboyina Nagaraju, John Porter, Lori Reilly, Markus Rüegg, Joel Schneider, Pietro Spitali, Volker Straub, Lee Sweeney, Giorgio Tasca, Cathy Turner, Olav Veldhuizen, Jan Verschuuren, Susan Ward & Raffaella Willmann. (2017) Facilitating orphan drug development: Proceedings of the TREAT-NMD International Conference, December 2015, Washington, DC, USA. Neuromuscular Disorders 27:7, pages 693-701.
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Jeffrey J. WidrickMatthew S. AlexanderBenjamin Sanchez, Devin E. GibbsGenri KawaharaAlan H. Beggs & Louis M. Kunkel. (2016) Muscle dysfunction in a zebrafish model of Duchenne muscular dystrophy. Physiological Genomics 48:11, pages 850-860.
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Simvastatin offers new prospects for the treatment of Duchenne muscular dystrophy

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Simvastatin offers new prospects for the treatment of Duchenne muscular dystrophy

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