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Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration Volume 20, 2019 - Issue 3-4
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Research Article

Predicting the future of ALS: the impact of demographic change and potential new treatments on the prevalence of ALS in the United Kingdom, 2020–2116

Alison GowlandDepartment of Basic and Clinical Neuroscience, King’s College London, Maurice Wohl Clinical Neuroscience Institute, London, UK, View further author information
,
Sarah Opie-MartinDepartment of Basic and Clinical Neuroscience, King’s College London, Maurice Wohl Clinical Neuroscience Institute, London, UK, View further author information
,
Kirsten M. ScottDepartment of Clinical Neuroscience, University of Cambridge, Cambridge, UK, View further author information
,
Ashley R. JonesDepartment of Basic and Clinical Neuroscience, King’s College London, Maurice Wohl Clinical Neuroscience Institute, London, UK, View further author information
,
Puja R. MehtaDepartment of Basic and Clinical Neuroscience, King’s College London, Maurice Wohl Clinical Neuroscience Institute, London, UK, ;King’s College Hospital, London, UK, View further author information
,
Christine J. BattsKent and Canterbury Hospital, East Kent Hospital NHS University Foundation Trust, Canterbury, UK, View further author information
,
Cathy M. EllisKing’s College Hospital, London, UK, View further author information
,
P. Nigel LeighDepartment of Neuroscience, Brighton and Sussex Medical School, Trafford Centre for Biomedical Research, University of Sussex, Brighton, UK, and View further author information
,
Christopher E. ShawUnited Kingdom Dementia Research Institute, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UKORCID Iconhttp://orcid.org/0000-0003-0251-0146View further author information
ORCID Icon,
Jemeen SreedharanDepartment of Basic and Clinical Neuroscience, King’s College London, Maurice Wohl Clinical Neuroscience Institute, London, UK, ORCID Iconhttp://orcid.org/0000-0002-8682-6844View further author information
ORCID Icon &
Ammar Al-ChalabiDepartment of Basic and Clinical Neuroscience, King’s College London, Maurice Wohl Clinical Neuroscience Institute, London, UK, ;King’s College Hospital, London, UK, Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-4924-7712View further author information
ORCID Icon show all
Pages 264-274 | Received 16 Oct 2018, Accepted 17 Feb 2019, Published online: 09 Apr 2019

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Judith M. Burchardt, Xue W. Mei, Tom Ranger, Christopher J. McDermott, Aleksandar Radunovic, Carol Coupland & Julia Hippisley-Cox. (2022) Analysis of incidence of motor neuron disease in England 1998–2019: use of three linked datasets. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 23:5-6, pages 363-371.
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Sarah Opie-Martin, Lynn Ossher, Andrea Bredin, Anna Kulka, Neil Pearce, Kevin Talbot & Ammar Al-Chalabi. (2021) Motor Neuron Disease Register for England, Wales and Northern Ireland—an analysis of incidence in England. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 22:1-2, pages 86-93.
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Articles from other publishers (12)

Satoshi Yamashita, Nozomu Tawara, Kentaro Hara & Mitsuharu Ueda. (2023) Gender differences in clinical features at the initial examination of late-onset amyotrophic lateral sclerosis. Journal of the Neurological Sciences 451, pages 120697.
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Erin C. Hedges, Graham Cocks, Christopher E. Shaw & Agnes L. Nishimura. (2023) Generation of an Open-Access Patient-Derived iPSC Biobank for Amyotrophic Lateral Sclerosis Disease Modelling. Genes 14:5, pages 1108.
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Eva L Feldman, Stephen A Goutman, Susanne Petri, Letizia Mazzini, Masha G Savelieff, Pamela J Shaw & Gen Sobue. (2022) Amyotrophic lateral sclerosis. The Lancet 400:10360, pages 1363-1380.
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Elliot Hampsey, Marton Meszaros, Caroline Skirrow, Rebecca Strawbridge, Rosie H Taylor, Lazarus Chok, Dag Aarsland, Ammar Al-Chalabi, Ray Chaudhuri, Jack Weston, Emil Fristed, Aleksandra Podlewska, Olabisi Awogbemila & Allan H Young. (2022) Protocol for Rhapsody: a longitudinal observational study examining the feasibility of speech phenotyping for remote assessment of neurodegenerative and psychiatric disorders. BMJ Open 12:6, pages e061193.
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Samantha N. Cobos & Mariana P. Torrente. (2022) Epidrugs in Amyotrophic Lateral Sclerosis/Frontotemporal Dementia: Contextualizing a Role for Histone Kinase Inhibition in Neurodegenerative Disease. ACS Pharmacology & Translational Science 5:2, pages 134-137.
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James Grogan & Zachary Simmons. (2021) Physician‐hastened death in California for patients with amyotrophic lateral sclerosis: Part of a bigger picture . Muscle & Nerve 64:4, pages 381-384.
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Éilís Conroy, Polly Kennedy, Mark Heverin, Iracema Leroi, Emily Mayberry, Anita Beelen, Theocharis Stavroulakis, Leonard H. van den Berg, Christopher J. McDermott, Orla Hardiman & Miriam Galvin. (2021) Informal Caregivers in Amyotrophic Lateral Sclerosis: A Multi-Centre, Exploratory Study of Burden and Difficulties. Brain Sciences 11:8, pages 1094.
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Maria Elena Cicardi, Lara Marrone, Mimoun Azzouz & Davide Trotti. (2021) Proteostatic imbalance and protein spreading in amyotrophic lateral sclerosis. The EMBO Journal 40:10.
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Chris Miller, Stephen Apple, Jeremy S. Paige, Tara Grabowsky, Oodaye Shukla, Wendy Agnese & Charlotte Merrill. (2021) Current and Future Projections of Amyotrophic Lateral Sclerosis in the United States Using Administrative Claims Data. Neuroepidemiology 55:4, pages 275-285.
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Jamire M. Silva, Michelangela S. C. Nobre, Sonaly L. Albino, Lucas L. Lócio, Agnis P. S. Nascimento, Luciana Scotti, Marcus T. Scotti, João A. Oshiro-Junior, Maria C. A. Lima, Francisco J. B. Mendonça-Junior & Ricardo O. Moura. (2020) Secondary Metabolites with Antioxidant Activities for the Putative Treatment of Amyotrophic Lateral Sclerosis (ALS): “Experimental Evidences”. Oxidative Medicine and Cellular Longevity 2020, pages 1-22.
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Zoltán Papp, Piergiuseppe Agostoni, Julian Alvarez, Dominique Bettex, Stefan Bouchez, Dulce Brito, Vladimir Cˇerný, Josep Comin-Colet, Marisa G Crespo-Leiro, Juan F Delgado, Istvan Édes, Alexander A Eremenko, Dimitrios Farmakis, Francesco Fedele, Cândida Fonseca, Sonja Fruhwald, Massimo Girardis, Fabio Guarracino, Veli-Pekka Harjola, Matthias Heringlake, Antoine Herpain, Leo MA Heunks, Tryggve Husebye, Višnja Ivancan, Kristjan Karason, Sundeep Kaul, Matti Kivikko, Janek Kubica, Josep Masip, Simon Matskeplishvili, Alexandre Mebazaa, Markku S Nieminen, Fabrizio Oliva, Julius-Gyula Papp, John Parissis, Alexander Parkhomenko, Pentti Põder, Gerhard Pölzl, Alexander Reinecke, Sven-Erik Ricksten, Hynek Riha, Alain Rudiger, Toni Sarapohja, Robert HG Schwinger, Wolfgang Toller, Luigi Tritapepe, Carsten Tschöpe, Gerhard Wikström, Dirk von Lewinski, Bojan Vrtovec & Piero Pollesello. (2020) Levosimendan Efficacy and Safety. Journal of Cardiovascular Pharmacology Publish Ahead of Print.
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Sandra Carrera-Juliá, Mari Luz Moreno, Carlos Barrios, Jose Enrique de la Rubia Ortí & Eraci Drehmer. (2020) Antioxidant Alternatives in the Treatment of Amyotrophic Lateral Sclerosis: A Comprehensive Review. Frontiers in Physiology 11.
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