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Tissue Barriers Volume 9, 2021 - Issue 1
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Review

The blood-brain barrier dysfunction in sepsis

Tatiana Barichelloa Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil;b Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, TX, USACorrespondence[email protected]
,
Jaqueline S. Generosoa Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, BrazilORCID Iconhttps://orcid.org/0000-0003-0571-6764
ORCID Icon,
Allan Collodela Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil
,
Fabricia Petronilhoc Laboratory of Neurobiology of Inflammatory and Metabolic Processes, Graduate Program in Health Sciences, Health Sciences Unit, University of South Santa Catarina, Tubarão, Brazil
&
Felipe Dal-Pizzola Laboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil
Article: 1840912 | Received 28 Aug 2020, Accepted 19 Oct 2020, Published online: 15 Dec 2020

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Mu-Huo Ji, Yu-Zhu Gao, Cui-Na Shi, Xin-Miao Wu & Jian-Jun Yang. (2023) Acute and long-term cognitive impairment following sepsis: mechanism and prevention. Expert Review of Neurotherapeutics 0:0, pages 1-13.
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Evans O. Ayieng’a, Elham A. Afify, Salwa A. Abuiessa, Samar S. Elblehi, Sahar M. El-Gowilly & Mahmoud M. El-Mas. (2023) Morphine aggravates inflammatory, behavioral, and hippocampal structural deficits in septic rats. Scientific Reports 13:1.
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Nan Zhao, Tracy D. Chung, Zhaobin Guo, John J. Jamieson, Lily Liang, Raleigh M. Linville, Alex F. Pessell, Linus Wang & Peter C. Searson. (2023) The influence of physiological and pathological perturbations on blood-brain barrier function. Frontiers in Neuroscience 17.
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Amany E. El-Naggar, Mai M. Helmy, Sahar M. El-Gowilly & Mahmoud M. El-Mas. (2023) Adenosine A1 receptors of the medullary solitary tract arbitrate the nicotine counteraction of neuroinflammation and cardiovascular dysfunction in septic rats. Scientific Reports 13:1.
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Min Wang, Jun Feng, Daixing Zhou & Junshuai Wang. (2023) Bacterial lipopolysaccharide-induced endothelial activation and dysfunction: a new predictive and therapeutic paradigm for sepsis. European Journal of Medical Research 28:1.
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Chuan Geng, Baoji Hu, Jihong Jiang, Yunhe Zhang, Weiqing Tang, Mengzhi Pan, Leilei Sun, Peifen Chen & Hengyue Wang. (2023) The effect of intravenous lidocaine on postoperative cognitive dysfunction: a systematic review and meta-analysis. BMC Anesthesiology 23:1.
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Ziyuan Li, Hui Wang & Yafu Yin. (2023) Peripheral inflammation is a potential etiological factor in Alzheimer’s disease. Reviews in the Neurosciences 0:0.
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Pengfei Li & Hongkuan Fan. (2023) Pericyte Loss in Diseases. Cells 12:15, pages 1931.
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Vijayasree V. Giridharan, Celso S. G. Catumbela, Carlos Henrique R. Catalão, Juneyoung Lee, Bhanu P. Ganesh, Fabricia Petronilho, Felipe Dal-Pizzol, Rodrigo Morales & Tatiana Barichello. (2023) Sepsis exacerbates Alzheimer’s disease pathophysiology, modulates the gut microbiome, increases neuroinflammation and amyloid burden. Molecular Psychiatry.
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Guanglu Wang, Yong Sun, Qiankun Yang, Dapeng Dai, Le Zhang, Hui Fan, Wei Zhang, Jingquan Dong & Panpan Zhao. (2023) Liensinine, a alkaloid from lotus plumule, mitigates lipopolysaccharide-induced sepsis-associated encephalopathy through modulation of nuclear factor erythroid 2-related factor-mediated inflammatory biomarkers and mitochondria apoptosis. Food and Chemical Toxicology 177, pages 113813.
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Sufang Jiang, Dandan Shi, Long Bai, Tianfu Niu, Rongtian Kang & Ya Liu. (2023) Inhibition of interleukin-6 trans-signaling improves survival and prevents cognitive impairment in a mouse model of sepsis. International Immunopharmacology 119, pages 110169.
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Adriana Marques, Carla Torre, Rui Pinto, Bruno Sepodes & João Rocha. (2023) Treatment Advances in Sepsis and Septic Shock: Modulating Pro- and Anti-Inflammatory Mechanisms. Journal of Clinical Medicine 12:8, pages 2892.
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Reenu Thomas, Merijn W. Bijlsma, Bronner P. Gonçalves, Firdose L. Nakwa, Sithembiso Velaphi & Paul T. Heath. (2023) Long-term impact of serious neonatal bacterial infections on neurodevelopment. Clinical Microbiology and Infection.
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Yuewen Xin, Mi Tian, Shuixiang Deng, Jiaying Li, Miaoxian Yang, Jianpeng Gao, Xu Pei, Yao Wang, Jiaying Tan, Feng Zhao, Yanqin Gao & Ye Gong. (2022) The Key Drivers of Brain Injury by Systemic Inflammatory Responses after Sepsis: Microglia and Neuroinflammation. Molecular Neurobiology 60:3, pages 1369-1390.
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Vijayasree V. Giridharan, Jaqueline S. Generoso, Leonardo Lence, Gabriela Candiotto, Emílio Streck, Fabricia Petronilho, Anilkumar Pillai, Tarek Sharshar, Felipe Dal-Pizzol & Tatiana Barichello. (2022) A crosstalk between gut and brain in sepsis-induced cognitive decline. Journal of Neuroinflammation 19:1.
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Lucinéia Gainski Danielski, Amanda Della Giustina, Fernanda Frederico Gava, Tatiana Barichello & Fabricia Petronilho. (2022) The Many Faces of Astrocytes in the Septic Brain. Molecular Neurobiology 59:12, pages 7229-7235.
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Diogo Dominguini, Monique Michels, Leticia B. Wessler, Emilio L. Streck, Tatiana Barichello & Felipe Dal-Pizzol. (2022) Mitochondrial protective effects caused by the administration of mefenamic acid in sepsis. Journal of Neuroinflammation 19:1.
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Carlos Henrique Rocha Catalão, Anderson de Oliveira Souza, Nilton Nascimento Santos-Junior, Luis Henrique Angenendt da Costa, Jonathas Rodrigo dos Santos, Luciane Carla Alberici & Maria José Alves Rocha. (2022) Pre-treatment and continuous administration of simvastatin during sepsis improve metabolic parameters and prevent CNS injuries in survivor rats. Molecular and Cellular Biochemistry 477:11, pages 2657-2667.
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Qiang Wen, Qian Ding, Jinchao Wang, Yanhua Yin, Shangchen Xu, Yuanrong Ju, Hongsheng Ji & Bin Liu. (2022) Cortistatin-14 Exerts Neuroprotective Effect Against Microglial Activation, Blood-brain Barrier Disruption, and Cognitive Impairment in Sepsis-associated Encephalopathy. Journal of Immunology Research 2022, pages 1-10.
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Yuanyuan Wang, Changli Wang, Dan Zhang, Liping Wang, Huihui Wang, Baoji Hu & Lulong Bo. (2022) Methane-rich saline protects against sepsis-associated cognitive deficits in mice. Brain Research 1791, pages 148000.
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Paul Lingor, Antonia F. Demleitner, Andreas W. Wolff & Emily Feneberg. (2022) SARS-CoV-2 and neurodegenerative diseases: what we know and what we don’t. Journal of Neural Transmission 129:9, pages 1155-1167.
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Xuan Lu, Yun-Mei Yang & Yuan-Qiang Lu. (2022) Immunosenescence: A Critical Factor Associated With Organ Injury After Sepsis. Frontiers in Immunology 13.
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Domonkos Pap, Apor Veres-Székely, Beáta Szebeni & Ádám Vannay. (2022) PARK7/DJ-1 as a Therapeutic Target in Gut-Brain Axis Diseases. International Journal of Molecular Sciences 23:12, pages 6626.
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Tatiana Barichello, Jaqueline S. Generoso, Diogo Dominguini, Emily Córneo, Vijayasree V. Giridharan, Taha A. Sahrapour, Lutiana R. Simões, Maria Inês da Rosa, Fabricia Petronilho, Cristiane Ritter, Tarek Sharshar & Felipe Dal-Pizzol. (2021) Postmortem Evidence of Brain Inflammatory Markers and Injury in Septic Patients: A Systematic Review. Critical Care Medicine 50:3, pages e241-e252.
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Tatiana Barichello, Jaqueline S. Generoso, Mervyn Singer & Felipe Dal-Pizzol. (2022) Biomarkers for sepsis: more than just fever and leukocytosis—a narrative review. Critical Care 26:1.
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Hao Jiang, Jiwei Gu, Haiyang Zhao, Sumit Joshi, Joel S. Perlmutter, Robert J. Gropler, Robyn S. Klein, Tammie L. S. Benzinger & Zhude Tu. (2021) PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection. Molecular Imaging 2021, pages 1-11.
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Kristine Farmen, Miguel Tofiño-Vian & Federico Iovino. (2021) Neuronal Damage and Neuroinflammation, a Bridge Between Bacterial Meningitis and Neurodegenerative Diseases. Frontiers in Cellular Neuroscience 15.
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