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Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 46, 2018 - Issue sup1: Supplement 1
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Original Paper

Pharmacokinetics, biodistribution and receptor mediated endocytosis of a natural Angelica sinensis polysaccharide

Yu Zhanga Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
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Tao Zhoua Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
,
Li Luoa Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
,
Zheng Cuia Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
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Na Wangb Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
,
Yamin Shub Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
&
Kai-Ping Wangb Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, ChinaCorrespondence[email protected]
View further author information
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Pages 254-263 | Received 26 Sep 2017, Accepted 20 Dec 2017, Published online: 01 Jan 2018

Citations (22)

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Xue Liu, Zhenfeng Wu, Chunjing Guo, Huimin Guo, Yanguo Su, Qiang Chen, Changgang Sun, Qingming Liu, Daquan Chen & Hongjie Mu. (2022) Hypoxia responsive nano-drug delivery system based on angelica polysaccharide for liver cancer therapy. Drug Delivery 29:1, pages 138-148.
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Articles from other publishers (21)

Dan Ye, Qing Zhao, Ding Ding & Bing-Liang Ma. (2023) Preclinical pharmacokinetics-related pharmacological effects of orally administered polysaccharides from traditional Chinese medicines: A review. International Journal of Biological Macromolecules 252, pages 126484.
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Yu Zhang, Niuniu Wu, Jingyi Wang, Zehong Chen, Zhijing Wu, Mengzi Song, Ziming Zheng & Kaiping Wang. (2023) Gastrointestinal metabolism characteristics and mechanism of a polysaccharide from Grifola frondosa. International Journal of Biological Macromolecules 253, pages 126357.
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Huanhuan Zhao, Qingyu Li, Anhua Shi, Ji Cui, Wenling Chen & Junzi Wu. (2022) Application of Plant Polysaccharide Nanoparticles as Polymeric Carrier Materials for the Construction of Medicine Carriers. Journal of Cluster Science 34:5, pages 2215-2228.
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Chunjing Guo, Min Cao, Ningning Diao, Wenxin Wang, Hongxu Geng, Yanguo Su, Tianying Sun, Xinyue Lu, Ming Kong & Daquan Chen. (2023) Novel pH-responsive E-selectin targeting natural polysaccharides hybrid micelles for diabetic nephropathy. Nanomedicine: Nanotechnology, Biology and Medicine 52, pages 102696.
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Hui Liu, Yuanyuan Zhao, Leijing Chen, Jiao Du, Hongyan Guo & Bin Wang. (2023) A Novel Method for the Pre-Column Derivatization of Saccharides from Polygonatum cyrtonema Hua. by Integrating Lambert–Beer Law and Response Surface Methodology. Molecules 28:5, pages 2186.
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Jie Shen, Mengyu Zhang, Ke Zhang, Yahan Qin, Meifang Liu, Shujuan Liang, Daquan Chen & Meiyu Peng. (2022) Effect of Angelica polysaccharide on mouse myeloid-derived suppressor cells. Frontiers in Immunology 13.
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Zhen Wang, Qiaoxu Sun, Yuanyuan Zhao, Jiao Du & Bin Wang. (2022) Synthesis of naphthalimide-type chemsensor and its application in quality evaluation for polygonatum sibiricum Red. Frontiers in Chemistry 10.
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Yun-yun Shao, Yi-nan Zhao, Yi-fan Sun, Yao Guo, Xiao Zhang, Zhuang-peng Chang, Rui-gang Hou & Jianping Gao. (2022) Investigation of the internalization and transport mechanism of Codonopsis Radix polysaccharide both in mice and Caco-2 cells. International Journal of Biological Macromolecules 215, pages 23-35.
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Natallia V. Dubashynskaya, Anton N. Bokatyi, Ekaterina R. Gasilova, Anatoliy V. Dobrodumov, Yaroslav A. Dubrovskii, Elena S. Knyazeva, Yuliya A. Nashchekina, Elena V. Demyanova & Yury A. Skorik. (2022) Hyaluronan-colistin conjugates: Synthesis, characterization, and prospects for medical applications. International Journal of Biological Macromolecules 215, pages 243-252.
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Yao Guo, Yun-yun Shao, Yi-nan Zhao, Xiao Zhang, Zhuang-peng Chang, Yi-fan Sun, Jun-jin Liu, Jianping Gao & Rui-gang Hou. (2022) Pharmacokinetics, distribution and excretion of inulin-type fructan CPA after oral or intravenous administration to mice. Food & Function 13:7, pages 4130-4141.
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Fei Li, Yunlu Wei, Jing Zhao, Luyao Zhang & Quanhong Li. (2022) In vivo pharmacokinetic study of a Cucurbita moschata polysaccharide after oral administration. International Journal of Biological Macromolecules 203, pages 19-28.
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Guanzhen Gao, Chuanqi He, Huiqin Wang, Jingke Guo, Lijing Ke, Jianwu Zhou, Pik Han Chong & Pingfan Rao. (2021) Polysaccharide Nanoparticles from Isatis indigotica Fort. Root Decoction: Diversity, Cytotoxicity, and Antiviral Activity. Nanomaterials 12:1, pages 30.
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Hui Xia, Chao Yang, Beijia Zhou, Huali Tang, Ligang Yang, Wang Liao & Guiju Sun. (2021) Pharmacokinetics and Excretion Study of Lycium barbarum Polysaccharides in Rats by FITC-Fluorescence Labeling. Foods 10:11, pages 2851.
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Jijuan Nai, Chao Zhang, Huili Shao, Bingqian Li, Huan Li, Lei Gao, Mengmeng Dai, Liqiao Zhu & Huagang Sheng. (2021) Extraction, structure, pharmacological activities and drug carrier applications of Angelica sinensis polysaccharide. International Journal of Biological Macromolecules 183, pages 2337-2353.
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Yue Cheng, Ying Xie, Ji-chun Ge, Lei Wang, Dai-yin Peng, Nian-jun Yu, Yue Zhang, Yue-hang Jiang, Jian-ping Luo & Wei-dong Chen. (2021) Structural characterization and hepatoprotective activity of a galactoglucan from Poria cocos. Carbohydrate Polymers 263, pages 117979.
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Chunjing Guo, Xiaoya Hou, Yanhui Liu, Yanchun Zhang, Haiyu Xu, Feng Zhao & Daquan Chen. (2021) Novel Chinese Angelica Polysaccharide Biomimetic Nanomedicine to Curcumin Delivery for Hepatocellular Carcinoma Treatment and Immunomodulatory Effect. Phytomedicine 80, pages 153356.
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Lijun Ling, Wenxia Ma, Zibin Li, Zhenglong Jiao, Xiaoyan Xu, Lu Lu, Xi Zhang, Juanjuan Feng & Ji Zhang. (2020) Comparative study of the endophytic and rhizospheric bacterial diversity of Angelica sinensis in three main producing areas in Gansu, China. South African Journal of Botany 134, pages 36-42.
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Ziming Zheng, Xianglin Pan, Jingya Xu, Zhijing Wu, Yu Zhang & Kaiping Wang. (2020) Advances in tracking of polysaccharides in vivo: Labeling strategies, potential factors and applications based on pharmacokinetic characteristics. International Journal of Biological Macromolecules 163, pages 1403-1420.
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Kaiping Wang, Jingya Xu, Yan Liu, Zheng Cui, Zihao He, Ziming Zheng, Xiao Huang & Yu Zhang. (2020) Self-assembled Angelica sinensis polysaccharide nanoparticles with an instinctive liver-targeting ability as a drug carrier for acute alcoholic liver damage protection. International Journal of Pharmaceutics 577, pages 118996.
Crossref
Li-Feng LI, Tin-Long WONG & Quan-Bin HAN. (2019) Difficulties in research of Chinese medicine polysaccharides. Chinese Journal of Natural Medicines 17:12, pages 883-886.
Crossref
Xiaoyan Xie, Miao Liu & Qiang Meng. (2019) Angelica polysaccharide promotes proliferation and osteoblast differentiation of mesenchymal stem cells by regulation of long non-coding RNA H19. Bone & Joint Research 8:7, pages 323-332.
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