Search in:

Emerging Microbes & Infections Volume 8, 2019 - Issue 1

Submit an article Journal homepage

Open access

8,167

Views

CrossRef citations to date

Altmetric

Articles

Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells

Sujit Pujharia Department of Entomology, Center for Infectious Disease Dynamics and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA

https://orcid.org/0000-0001-5856-5328 View further author information

Marco Brustolina Department of Entomology, Center for Infectious Disease Dynamics and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA

https://orcid.org/0000-0002-3594-4488 View further author information

Vanessa M. Maciasa Department of Entomology, Center for Infectious Disease Dynamics and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA

https://orcid.org/0000-0002-8008-7403 View further author information

Ruth H. Nisslyb Animal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, USA

https://orcid.org/0000-0002-3102-7447 View further author information

Masashi Nomuraa Department of Entomology, Center for Infectious Disease Dynamics and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA;c Graduate School of Horticulture, Chiba University, Japan

https://orcid.org/0000-0003-1455-9422 View further author information

Suresh V. Kuchipudib Animal Diagnostic Laboratory, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, USA

https://orcid.org/0000-0002-8640-254X View further author information

Jason L. Rasgona Department of Entomology, Center for Infectious Disease Dynamics and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USACorrespondence[email protected]

https://orcid.org/0000-0002-4050-8429 View further author information

show all

Pages 8-16 | Received 04 Dec 2018, Accepted 06 Dec 2018, Published online: 16 Jan 2019

Cite this article
https://doi.org/10.1080/22221751.2018.1557988
CrossMark

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF View EPUB EPUB

Citations (55)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Articles from other publishers (55)

Erica Diani, Anna Lagni, Virginia Lotti, Emil Tonon, Riccardo Cecchetto & Davide Gibellini. (2023) Vector-Transmitted Flaviviruses: An Antiviral Molecules Overview. Microorganisms 11:10, pages 2427.
Crossref

Yifei Feng, Yan Yang, Shuting Zou, Shuqi Qiu, Hao Yang, Yi Hu, Guifen Lin, Xingang Yao, Shuwen Liu & Min Zou. (2023) Identification of alpha-linolenic acid as a broad-spectrum antiviral against zika, dengue, herpes simplex, influenza virus and SARS-CoV-2 infection. Antiviral Research, pages 105666.
Crossref

Peiwen Zhou, Zizhao Lao, Haishan Long, Pan Pan, Feng Liao, Wenjiang Zheng, Zonghui Li, Jianfeng Dai, Helu Liu, Yong Jiang, Xiaohong Liu, Wenbiao Wang, Jianguo Wu & Geng Li. (2023) The in vitro and in vivo antiviral effects of aloperine against Zika virus infection. Journal of Medical Virology 95:7.
Crossref

Nannan Chen, Tongtong Bai, Shuang Wang, Huan Wang, Yue Wu, Yu Liu & Zhanbo Zhu. (2023) New Insights into the Role and Therapeutic Potential of Heat Shock Protein 70 in Bovine Viral Diarrhea Virus Infection. Microorganisms 11:6, pages 1473.
Crossref

Maria Sole Burali, Violetta Cecchetti & Giuseppe Manfroni. (2023) Broad-Spectrum Anti-Flavivirus Activity and Chemistry of Compounds Containing Sulfur and Oxygen Chalcogens. Current Medicinal Chemistry 30:21, pages 2396-2420.
Crossref

Huandong Zhang, Houli Cai, Qingyang Li, Chengxiu Fang, Li Peng, Jianing Lan, Jiyong Zhou & Min Liao. (2023) Identification of Host Proteins Interacting with IBV S1 Based on Tracheal Organ Culture. Viruses 15:5, pages 1216.
Crossref

Ling Kong, Jie Xiao, Lu Yang, Yuan Sui, Duoquan Wang, Shaoqiang Chen, Peiwen Liu, Xiao-Guang Chen & Jinbao Gu. (2023) Mosquito densovirus significantly reduces the vector susceptibility to dengue virus serotype 2 in Aedes albopictus mosquitoes (Diptera: Culicidae). Infectious Diseases of Poverty 12:1.
Crossref

Quang Duy Trinh, Ngan Thi Kim Pham, Kazuhide Takada, Hiroshi Ushijima, Shihoko Komine-Aizawa & Satoshi Hayakawa. (2023) Roles of TGF-β1 in Viral Infection during Pregnancy: Research Update and Perspectives. International Journal of Molecular Sciences 24:7, pages 6489.
Crossref

Shuang Wu, Yongtian Zhao, Delu Wang & Zhuo Chen. (2023) Mode of Action of Heat Shock Protein (HSP) Inhibitors against Viruses through Host HSP and Virus Interactions. Genes 14:4, pages 792.
Crossref

Nannan Chen, Yu Liu, Tongtong Bai, Jinwei Chen, Zhibo Zhao, Jing Li, Baihui Shao, Zecai Zhang, Yulong Zhou, Xue Wang & Zhanbo Zhu. (2022) Quercetin Inhibits Hsp70 Blocking of Bovine Viral Diarrhea Virus Infection and Replication in the Early Stage of Virus Infection. Viruses 14:11, pages 2365.
Crossref

Sujit Pujhari, Marco Brustolin, Chan C. Heu, Ronald Smithwick, Mireia Larrosa, Susan Hafenstein & Jason L. Rasgon. (2022) Characterization of Mayaro virus (strain BeAn343102) biology in vertebrate and invertebrate cellular backgrounds. Journal of General Virology 103:10.
Crossref

Do Thi Minh Xuan, I-Jeng Yeh, Chung-Che Wu, Che-Yu Su, Hsin-Liang Liu, Chung-Chieh Chiao, Su-Chi Ku, Jia-Zhen Jiang, Zhengda Sun, Hoang Dang Khoa Ta, Gangga Anuraga, Chih-Yang Wang & Meng-Chi Yen. (2022) Comparison of Transcriptomic Signatures between Monkeypox-Infected Monkey and Human Cell Lines. Journal of Immunology Research 2022, pages 1-17.
Crossref

Pingping Sun, Qiang Ma & Lei Zhang. (2022) Comprehensive acetyl-proteomic analysis of Cytospora mali provides insight into its response to the biocontrol agent Bacillus velezensis L-1. Frontiers in Sustainable Food Systems 6.
Crossref

Celine Caillet, Melissa Louise Stofberg, Victor Muleya, Addmore Shonhai & Tawanda Zininga. (2022) Host cell stress response as a predictor of COVID-19 infectivity and disease progression. Frontiers in Molecular Biosciences 9.
Crossref

Kangchen Li, Qianting Ji, Shibo Jiang & Naru Zhang. (2022) Advancement in the Development of Therapeutics Against Zika Virus Infection. Frontiers in Cellular and Infection Microbiology 12.
Crossref

Priyanka & Pankaj Seth. (2022) Insights Into the Role of Mortalin in Alzheimer’s Disease, Parkinson’s Disease, and HIV-1-Associated Neurocognitive Disorders. Frontiers in Cell and Developmental Biology 10.
Crossref

Blanka Tesla, Jenna S. Powers, Yvonne Barnes, Shamil Lakhani, Marissa D. Acciani & Melinda A. Brindley. (2022) Temperate Conditions Limit Zika Virus Genome Replication. Journal of Virology 96:10.
Crossref

Haley S. Caldwell, Janice D. Pata & Alexander T. Ciota. (2022) The Role of the Flavivirus Replicase in Viral Diversity and Adaptation. Viruses 14:5, pages 1076.
Crossref

Ge Dai, Kaikai Han, Xinmei Huang, Lijiao Zhang, Qingtao Liu, Jing Yang, Yuzhuo Liu, Yin Li & Dongmin Zhao. (2022) Heat shock protein 70 (HSP70) plays important role in tembusu virus infection. Veterinary Microbiology 267, pages 109377.
Crossref

Thamil Vaani Komarasamy, Nur Amelia Azreen Adnan, William James & Vinod R. M. T. Balasubramaniam. (2022) Zika Virus Neuropathogenesis: The Different Brain Cells, Host Factors and Mechanisms Involved. Frontiers in Immunology 13.
Crossref

Adam T. Fishburn, Oanh H. Pham, Matthew W. Kenaston, Nitin S. Beesabathuni & Priya S. Shah. (2022) Let’s Get Physical: Flavivirus-Host Protein–Protein Interactions in Replication and Pathogenesis. Frontiers in Microbiology 13.
Crossref

Jie Li, Wenyu Pan, Shuling Zhao & Changyong Liang. (2022) Heat shock cognate protein 70 is required for rice stripe tenuivirus accumulation and transmission in small brown planthopper. Archives of Virology 167:3, pages 839-848.
Crossref

Jian Yang, Jia Wang, Xiaowei Peng, Chengfeng Lei, Xiulian Sun & Jia Hu. (2021) Heat shock protein 70, glutamate dehydrogenase, and angiotensin-converting enzyme of Bombyx mori mediate the cell attachment of Cypovirus 1. Journal of General Virology 102:12.
Crossref

Tao Hu, Zhen Wu, Shaoxiong Wu, Shun Chen & Anchun Cheng. (2021) The key amino acids of E protein involved in early flavivirus infection: viral entry. Virology Journal 18:1.
Crossref

Weichen Xiong, Jingyan Li, Yifei Feng, Jinwei Chai, Jiena Wu, Yunrui Hu, Maolin Tian, Wancheng Lu, Xueqing Xu & Min Zou. (2021) Brevinin-2GHk, a Peptide Derived from the Skin of Fejervarya limnocharis, Inhibits Zika Virus Infection by Disrupting Viral Integrity. Viruses 13:12, pages 2382.
Crossref

Khoshnur Jannat, Alok K. Paul, Tohmina A. Bondhon, Anamul Hasan, Muhammad Nawaz, Rownak Jahan, Tooba Mahboob, Veeranoot Nissapatorn, Polrat Wilairatana, Maria de Lourdes Pereira & Mohammed Rahmatullah. (2021) Nanotechnology Applications of Flavonoids for Viral Diseases. Pharmaceutics 13:11, pages 1895.
Crossref

Lim Jack Lee, Thamil Vaani Komarasamy, Nur Amelia Azreen Adnan, William James & Vinod RMT Balasubramaniam. (2021) Hide and Seek: The Interplay Between Zika Virus and the Host Immune Response. Frontiers in Immunology 12.
Crossref

Catarina Sabino, Daniela Bender, Marie-Luise Herrlein & Eberhard Hildt. (2021) The Epidermal Growth Factor Receptor Is a Relevant Host Factor in the Early Stages of The Zika Virus Life Cycle In Vitro . Journal of Virology 95:20.
Crossref

Jim Zoladek, Vincent Legros, Patricia Jeannin, Maxime Chazal, Nathalie Pardigon, Pierre-Emmanuel Ceccaldi, Antoine Gessain, Nolwenn Jouvenet & Philippe V. Afonso. (2021) Zika Virus Requires the Expression of Claudin-7 for Optimal Replication in Human Endothelial Cells. Frontiers in Microbiology 12.
Crossref

Supreeti Mahajan, Shweta Choudhary, Pravindra Kumar & Shailly Tomar. (2021) Antiviral strategies targeting host factors and mechanisms obliging +ssRNA viral pathogens. Bioorganic & Medicinal Chemistry 46, pages 116356.
Crossref

Anna Lubkowska, Waldemar Pluta, Aleksandra Strońska & Alicja Lalko. (2021) Role of Heat Shock Proteins (HSP70 and HSP90) in Viral Infection. International Journal of Molecular Sciences 22:17, pages 9366.
Crossref

Kevin J. Maroney, Amanda N. Pinski, Andrea Marzi & Ilhem Messaoudi. (2021) Transcriptional Analysis of Infection With Early or Late Isolates From the 2013–2016 West Africa Ebola Virus Epidemic Does Not Suggest Attenuated Pathogenicity as a Result of Genetic Variation. Frontiers in Microbiology 12.
Crossref

Fhallon Ware-Gilmore, Carla M. Sgrò, Zhiyong Xi, Heverton L. C. Dutra, Matthew J. Jones, Katriona Shea, Matthew D. Hall, Matthew B. Thomas & Elizabeth A. McGraw. (2021) Microbes increase thermal sensitivity in the mosquito Aedes aegypti, with the potential to change disease distributions. PLOS Neglected Tropical Diseases 15:7, pages e0009548.
Crossref

Andrew J. Ambrose & Eli Chapman. (2021) Function, Therapeutic Potential, and Inhibition of Hsp70 Chaperones. Journal of Medicinal Chemistry 64:11, pages 7060-7082.
Crossref

Cheorl-Ho Kim. (2021) Anti–SARS-CoV-2 Natural Products as Potentially Therapeutic Agents. Frontiers in Pharmacology 12.
Crossref

Dahan Yang, Xiaoping Lv, Shujun Zhang & Shimin Zheng. (2021) Tandem Mass Tag-Based Quantitative Proteomic Analysis of Chicken Bursa of Fabricius Infected With Reticuloendotheliosis Virus. Frontiers in Veterinary Science 8.
Crossref

Yiming Zhang, Rory A Greer, Yuwei Song, Hrithik Praveen & Yuhua Song. (2021) In silico identification of available drugs targeting cell surface BiP to disrupt SARS-CoV-2 binding and replication: Drug repurposing approach. European Journal of Pharmaceutical Sciences 160, pages 105771.
Crossref

Moujian Guo, Lixia Hui, Yiwen Nie, Boris Tefsen & Ying Wu. (2020) ZIKV viral proteins and their roles in virus-host interactions. Science China Life Sciences 64:5, pages 709-719.
Crossref

Sineewanlaya Wichit, Nuttamonpat Gumpangseth, Rodolphe Hamel, Sakda Yainoy, Siwaret Arikit, Chuchard Punsawad & Dorothée Missé. (2021) Chikungunya and Zika Viruses: Co-Circulation and the Interplay between Viral Proteins and Host Factors. Pathogens 10:4, pages 448.
Crossref

Lucas Belon, Peter Skidmore, Rohan Mehra & Edward Walter. (2021) Effect of a fever in viral infections — the ‘Goldilocks’ phenomenon?. World Journal of Clinical Cases 9:2, pages 296-307.
Crossref

Rishya Manikam, Soe Hui Jen, Amni Adilah Ismail, Chandramathi Samudi Raju & Shamala Devi Sekaran. 2021. Zika Virus Biology, Transmission, and Pathology. Zika Virus Biology, Transmission, and Pathology 209 220 .

Ming-Liang He, Qianya Wan, Dan Song & Betsy He. 2021. Oxidative Stress. Oxidative Stress 77 102 .

Ana I. Núñez, Anna Esteve-Codina, Jèssica Gómez-Garrido, Marco Brustolin, Sandra Talavera, Miguel Berdugo, Marc Dabad, Tyler Alioto, Albert Bensaid & Núria Busquets. (2020) Alteration in the Culex pipiens transcriptome reveals diverse mechanisms of the mosquito immune system implicated upon Rift Valley fever phlebovirus exposure. PLOS Neglected Tropical Diseases 14:12, pages e0008870.
Crossref

Kitipong Angsujinda, Timothy J. Mahony, Duncan R. Smith, Jes Kettratad & Wanchai Assavalapsakul. (2020) Expression profile of selected genes of the E-11 cell line in response to red-spotted grouper nervous necrosis virus infection. Aquaculture Reports 18, pages 100468.
Crossref

Letizia Paladino, Alessandra Maria Vitale, Celeste Caruso Bavisotto, Everly Conway de Macario, Francesco Cappello, Alberto J.L. Macario & Antonella Marino Gammazza. (2020) The Role of Molecular Chaperones in Virus Infection and Implications for Understanding and Treating COVID-19. Journal of Clinical Medicine 9:11, pages 3518.
Crossref

Alexander S. Gold, Fabiana Feitosa-Suntheimer, Ricardo V. Araujo, Ryan M. Hekman, Sultan Asad, Berlin Londono-Renteria, Andrew Emili & Tonya M. Colpitts. (2020) Dengue Virus Infection of Aedes aegypti Alters Extracellular Vesicle Protein Cargo to Enhance Virus Transmission. International Journal of Molecular Sciences 21:18, pages 6609.
Crossref

Xingyue Ji & Zhuorong Li. (2020) Medicinal chemistry strategies toward host targeting antiviral agents. Medicinal Research Reviews 40:5, pages 1519-1557.
Crossref

Rafael Guerrero, Carlos Guerrero & Orlando Acosta. (2020) Induction of Cell Death in the Human Acute Lymphoblastic Leukemia Cell Line Reh by Infection with Rotavirus Isolate Wt1-5. Biomedicines 8:8, pages 242.
Crossref

Quanshi Lin, Shili Zhou, Yanxia Huang, Zhiting Huo, Cancan Chen, Xin Luo, Junfang He, Chao Liu & Ping Zhang. (2020) ANKS4B Restricts Replication of Zika Virus by Downregulating the Autophagy. Frontiers in Microbiology 11.
Crossref

Yang Wang, Hui Zhang, Dongbo Ma, Xiang Deng, Dongdong Wu, Fang Li, Qiuge Wu, Hong Liu & Jing Wang. (2020) Hsp70 Is a Potential Therapeutic Target for Echovirus 9 Infection. Frontiers in Molecular Biosciences 7.
Crossref

Qianya Wan, Dan Song, Huangcan Li & Ming-liang He. (2020) Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development. Signal Transduction and Targeted Therapy 5:1.
Crossref

Cheorl-Ho Kim. (2020) SARS-CoV-2 Evolutionary Adaptation toward Host Entry and Recognition of Receptor O-Acetyl Sialylation in Virus–Host Interaction. International Journal of Molecular Sciences 21:12, pages 4549.
Crossref

Jingjing Yang, Yongfen Xu, Yunzheng Yan, Wei Li, Lei Zhao, Qingsong Dai, Yuexiang Li, Song Li, Jin Zhong, Ruiyuan Cao & Wu Zhong. (2020) Small Molecule Inhibitor of ATPase Activity of HSP70 as a Broad-Spectrum Inhibitor against Flavivirus Infections. ACS Infectious Diseases 6:5, pages 832-843.
Crossref

Justin A. Roby, Katharina Esser-Nobis, Elyse C. Dewey-Verstelle, Marian R. Fairgrieve, Johannes Schwerk, Amy Y. Lu, Frank W. Soveg, Emily A. Hemann, Lauren D. Hatfield, Brian C. Keller, Alexander Shapiro, Adriana Forero, Jennifer E. Stencel-Baerenwald, Ram Savan & Michael GaleJr.Jr.. (2020) Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling. Cells 9:4, pages 899.
Crossref

Fanzhi Kong, Yaru Xu, Wei Ran, Baishuang Yin, Li Feng & Dongbo Sun. (2020) Cold Exposure-Induced Up-Regulation of Hsp70 Positively Regulates PEDV mRNA Synthesis and Protein Expression In Vitro. Pathogens 9:4, pages 246.
Crossref

Share icon
Back to Top

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells

Articles from other publishers (55)

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells

Citations (55)

Articles from other publishers (55)

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date