A standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patients

Guangxin Yua State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of ChinaView further author information

Ran Chena State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of China;b Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, People’s Republic of ChinaView further author information

Sujun Zhengc Hepatology Center Department, Beijing YouAn Hospital, Capital Medical University, Beijing, People’s Republic of ChinaView further author information

Yanna Liua State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of ChinaView further author information

Jun Zoua State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of ChinaView further author information

Zhiqiang Gua State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of ChinaView further author information

Bei Jiangd Tianjin Institute of Hepatology, Tianjin Second People’s Hospital, Tianjin, People’s Republic of ChinaView further author information

Qi Gaoe Beijing Hotgen Biotech Co., Ltd., Beijing, People’s Republic of ChinaView further author information

Lizhong Daif Sansure Biotechnology Corporation, Changsha, People’s Republic of ChinaCorrespondence[email protected]
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Jie Pengg Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence[email protected]

https://orcid.org/0000-0003-0928-3134 View further author information

Jie Wanga State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of ChinaCorrespondence[email protected]

https://orcid.org/0000-0001-6518-948X View further author information

Fengmin Lua State Key Laboratory of Natural and Biomimetic Drugs, Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, People’s Republic of ChinaCorrespondence[email protected]

https://orcid.org/0000-0002-1832-3209 View further author information

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Liandong Wu, Zhenggang Yang & Min Zheng. (2024) Biogenesis of serum HBV RNA and clinical phenomena of serum HBV RNA in chronic hepatitis B patients before and after receiving nucleos(t)ide analogues therapy . Journal of Viral Hepatitis 31:5, pages 255-265.
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Michael X. Fu, Peter Simmonds, Monique Andersson & Heli Harvala. (2024) Biomarkers of transfusion transmitted occult hepatitis B virus infection: Where are we and what next?. Reviews in Medical Virology 34:2.
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Sulan Yu, Yanjuan Guo & Chunxiao Zhang. (2023) Serum HBV RNA: a promising biomarker for blood product safety screening and enhanced diagnostic efficiency in chronic hepatitis B virus infection. Frontiers in Public Health 11.
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Yang Shi, Zihan Wang, Shengxiang Ge, Ningshao Xia & Quan Yuan. (2023) Hepatitis B Core Antibody Level: A Surrogate Marker for Host Antiviral Immunity in Chronic Hepatitis B Virus Infections. Viruses 15:5, pages 1111.
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Jules Sotty, Pierre Bablon, Bouchra Lekbaby, Jérémy Augustin, Morgane Girier-Dufournier, Lucas Langlois, Céline Dorival, Fabrice Carrat, Stanislas Pol, Hélène Fontaine, Nazim Sarica, Christine Neuveut, Chantal Housset, Dina Kremdsorf, Aurélie Schnuriger & Patrick Soussan. (2022) Diversity of the nucleic acid forms of circulating HBV in chronically infected patients and its impact on viral cycle. Hepatology International 16:6, pages 1259-1272.
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Alicia Vachon, Elizabeth Giles, Nishi Patel, Alexandra Presbitero, Muhammad Atif Zahoor, Carla S. Coffin, Jordan J Feld, Curtis L. Cooper & Carla Osiowy. (2022) Analytical and clinical validation of 3′ RACE RT-qPCR assay for detection and quantification of hepatitis B virus (HBV) serum RNA. Journal of Clinical Virology Plus 2:4, pages 100126.
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Thomas Tu, Florian van Bömmel & Thomas Berg. (2022) Surrogate Markers for Hepatitis B Virus Covalently Closed Circular DNA. Seminars in Liver Disease 42:03, pages 327-340.
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A standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patients

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A standardized assay for the quantitative detection of serum HBV RNA in chronic hepatitis B patients

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