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Emerging Microbes & Infections Volume 11, 2022 - Issue 1
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Coronaviruses

Combining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovirus-based COVID-19 vaccine elicits potent humoral and cellular immune responses in mice

Xingxing Lia Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Ling Wangb State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, People’s Republic of China
,
Jingjing Liua Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Enyue Fanga Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Xiaohui Liua Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Qinhua Penga Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Zelun Zhanga Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Miao Lia Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Xinyu Liua Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Xiaohong Wua Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Danhua Zhaoa Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Lihong Yanga Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Jia Lia Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Shouchun Caoa Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Yanqiu Huanga Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Leitai Shia Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Hongshan Xua Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Yunpeng Wanga Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Yue Suoa Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Guangzhi Yuea Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Jianhui Niec Department of HIV/AIDS and Sex-transmitted Virus Vaccines, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
,
Weijin Huangc Department of HIV/AIDS and Sex-transmitted Virus Vaccines, National Institutes for Food and Drug Control, Beijing, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-4246-8889
ORCID Icon,
Wenjuan Lia Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of ChinaCorrespondence[email protected]
&
Yuhua Lia Department of Arboviral Vaccine, National Institutes for Food and Drug Control, Beijing, People’s Republic of ChinaCorrespondence[email protected]
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Pages 1890-1899 | Received 27 Mar 2022, Accepted 29 Jun 2022, Published online: 27 Jul 2022

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Shen-Yu Wang, Wen-Qing Liu, Yu-Qing Li, Jing-Xin Li & Feng-Cai Zhu. (2023) A China-developed adenovirus vector-based COVID-19 vaccine: review of the development and application of Ad5-nCov. Expert Review of Vaccines 22:1, pages 704-713.
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