Enterovirus-A71 Preferentially Infects and Replicates in Human Motor Neurons, Inducing Neurodegeneration by Ferroptosis

Wai Hon Chooi1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.

Winanto1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.;2 National University of Singapore, Faculty of Science (Department of Biological Science), Singapore117543

Yingying Zeng1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.

Chery1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.

Yi-Pin Lim1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.

Ze Qin Lim3 Infectious Diseases Translational Research Programme (IDTRP); Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore117545.;4 Immunology programme, Life Science Institute, National University of Singapore, Singapore117456.

Pradeep Gautam1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.

Justin Jang Hann Chu1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.;3 Infectious Diseases Translational Research Programme (IDTRP); Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore117545.

Yuin-Han Loh1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.

Sylvie Alonso3 Infectious Diseases Translational Research Programme (IDTRP); Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore117545.;4 Immunology programme, Life Science Institute, National University of Singapore, Singapore117456.Correspondence[email protected]

Shi-Yan Ng1 Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore138673, Republic of Singapore.;5 Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore117593.;6 National Neuroscience Institute, Singapore308433.Correspondence[email protected]

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Enterovirus-A71 Preferentially Infects and Replicates in Human Motor Neurons, Inducing Neurodegeneration by Ferroptosis

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Enterovirus-A71 Preferentially Infects and Replicates in Human Motor Neurons, Inducing Neurodegeneration by Ferroptosis

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