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Research Article

HPTLC-based quantification of camptothecin in Ophiorrhiza species of the southern Western Ghats in India

Renjith RajanPhytochemistry and Phytopharmacology Division, Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram695 562, Kerala, India
,
Sibi Chirakkadamoolayil VargheseBiotechnology and Bioinformatics Division, Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram695 562, Kerala, India
,
Rajani KurupPhytochemistry and Phytopharmacology Division, Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram695 562, Kerala, India
,
Roja GopalakrishnanNuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Mumbai400 085, Maharashtra, India
,
Ramaswamy VenkataramanDepartment of Chemistry, Sri Paramakalyani College, Manonmaniom Sundaranar University, Alwarkurichi, Tirunelveli627 412, Tamil Nadu, India
,
Krishnan SatheeshkumarBiotechnology and Bioinformatics Division, Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram695 562, Kerala, India
&
Sabulal BabyPhytochemistry and Phytopharmacology Division, Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram695 562, Kerala, IndiaCorrespondence[email protected] [email protected]
View further author information
|
Youcef MehellouUniversity of Birmingham, UK
(Reviewing Editor) show all
Article: 1275408 | Received 06 Oct 2016, Accepted 19 Dec 2016, Published online: 12 Jan 2017

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S. Ajikumaran Nair, Rajani Kurup Sukumaryamma Remadevi, Smrithi S. Lal, Reshma Raju, Raju Antony & Sabulal Baby. (2023) Chemical Composition and Antiproliferative Activity of Rhizome and Frond Essential Oils of Anemia schimperiana subsp. wightiana, a Rare Fern Endemic to South India. Journal of Biologically Active Products from Nature 13:2, pages 105-117.
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Renju Kunjumon, Anil John Johnson, Rajani Kurup Sukumaryamma Remadevi & Sabulal Baby. (2023) Dammarane-type triterpenoid saponin-rich elite genotypes of Bacopa monnieri from south India and their edaphic-ecological preferences. Industrial Crops and Products 202, pages 117075.
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Reshma Vijayakumari Raveendran Nair, Ajikumaran Nair Sadasivan Nair, Anil John Johnson, Ananthakrishnan Jayakumaran Nair & Sabulal Baby. (2023) Antiproliferative activity of secondary metabolites isolated from Humboldtia unijuga Bedd.. Medicinal Chemistry Research 32:6, pages 1163-1177.
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Renju Kunjumon, Anil John Johnson, Rajani Kurup Sukumaryamma Remadevi & Sabulal Baby. (2022) Influence of ecological factors on asiaticoside and madecassoside contents and biomass production in Centella asiatica from its natural habitats in south India. Industrial Crops and Products 189, pages 115809.
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Renju Kunjumon, Anil John Johnson & Sabulal Baby. 2022. Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda. Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda 176 200 .
Mariko Kitajima. (2022) Recent studies on chemical constituents of Ophiorrhiza plants. Journal of Natural Medicines 76:4, pages 748-755.
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Renju Kunjumon, Anil John Johnson, Rajani Kurup Sukumaryamma Remadevi & Sabulal Baby. (2022) Assessment of major centelloside ratios in Centella asiatica accessions grown under identical ecological conditions, bioconversion clues and identification of elite lines. Scientific Reports 12:1.
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Qingyan Ruan, Gopal Patel, Jingyi Wang, Enhui Luo, Wei Zhou, Elwira Sieniawska, Xiaolong Hao & Guoyin Kai. (2021) Current advances of endophytes as a platform for production of anti-cancer drug camptothecin. Food and Chemical Toxicology 151, pages 112113.
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Wen-Zhe Xie, Hui-Xiang Yang, Zheng-Hui Li, Tao Feng & Ji-Kai Liu. (2021) Indole alkaloids from Ophiorrhiza cantoniensis with immunosuppressive activity. Fitoterapia 148, pages 104777.
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Bernhard Wetterauer, Eric Hummel, Steffen Walczak, Melanie Distl, Markus Langhans, Pille Wetterauer, Frank Sporer, Eckhart Wildi & Michael Wink. 2021. Exploring Plant Cells for the Production of Compounds of Interest. Exploring Plant Cells for the Production of Compounds of Interest 291 338 .
Muhammad Taher, Siti Syazwani Shaari, Deny Susanti, Dayar Arbain & Zainul Amiruddin Zakaria. (2020) Genus Ophiorrhiza: A Review of Its Distribution, Traditional Uses, Phytochemistry, Biological Activities and Propagation. Molecules 25:11, pages 2611.
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T. Pullaiah & V. Raveendran. 2020. Camptothecin and Camptothecin Producing Plants. Camptothecin and Camptothecin Producing Plants 47 103 .
Anil J. Johnson, Renjith Rajan & Sabulal Baby. (2019) Secondary Metabolites from Ophiorrhiza. The Natural Products Journal 8:4, pages 248-267.
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Jeeja Jaya Krishnan, A Gangaprasad & K Satheeshkumar. (2018) Exogenous methyl jasmonate acts as a signal transducer in the enhancement of camptothecin (CPT) production from in vitro cultures of Ophiorrhiza mungos L. var. angustifolia (Thw.) Hook. f.. Industrial Crops and Products 119, pages 93-101.
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Jeeja Jaya Krishnan, A. Gangaprasad & K. Satheeshkumar. (2018) In vitro mass multiplication and estimation of camptothecin (CPT) in Ophiorrhiza mungos L. var. angustifolia (Thw.) Hook. f.. Industrial Crops and Products 119, pages 64-72.
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