Advanced search
Publication Cover
Molecular & Cellular Oncology Volume 3, 2016 - Issue 2
Submit an article Journal homepage
2,820
Views
19
CrossRef citations to date
0
Altmetric
Commentary

Antitumor activity of LSD1 inhibitors in lung cancer

Helai P. MohammadCancer Epigenetics, GlaxoSmithKline, Collegeville, PA, USA
&
Ryan G. KrugerCancer Epigenetics, GlaxoSmithKline, Collegeville, PA, USACorrespondence[email protected]
Article: e1117700 | Received 29 Oct 2015, Accepted 04 Nov 2015, Published online: 04 Apr 2016

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Mirjam Hau, Fides Zenk, A. Ganesan, Nicola Iovino & Manfred Jung. (2017) Cellular analysis of the action of epigenetic drugs and probes. Epigenetics 12:5, pages 308-322.
Read now

Articles from other publishers (18)

Min Yuan, Yu Zhao, Hendrik-Tobias Arkenau, Tongnei Lao, Li Chu & Qing Xu. (2022) Signal pathways and precision therapy of small-cell lung cancer. Signal Transduction and Targeted Therapy 7:1.
Crossref
Natalia Sacilotto, Paola Dessanti, Michele M. P. Lufino, Alberto Ortega, Alejandra Rodríguez-Gimeno, Jordi Salas, Tamara Maes, Carlos Buesa, Cristina Mascaró & Robert Soliva. (2021) Comprehensive in Vitro Characterization of the LSD1 Small Molecule Inhibitor Class in Oncology . ACS Pharmacology & Translational Science 4:6, pages 1818-1834.
Crossref
Antoine Hollebecque, Stefania Salvagni, Ruth Plummer, Nicolas Isambert, Patricia Niccoli, Jaume Capdevila, Giuseppe Curigliano, Victor Moreno, Patricia Martin-Romano, Eric Baudin, Marina Arias, Sheila Mora, Juan de Alvaro, Jorge Di Martino, Josep L. Parra-Palau, Tania Sánchez-Pérez, Ida Aronchik, Ellen H. Filvaroff, Manisha Lamba, Zariana Nikolova & Johann S. de Bono. (2021) Phase I Study of Lysine-Specific Demethylase 1 Inhibitor, CC-90011, in Patients with Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin Lymphoma. Clinical Cancer Research 27:2, pages 438-446.
Crossref
Shanmuga Subbiah, Arin Nam, Natasha Garg, Amita Behal, Prakash Kulkarni & Ravi Salgia. (2020) Small Cell Lung Cancer from Traditional to Innovative Therapeutics: Building a Comprehensive Network to Optimize Clinical and Translational Research. Journal of Clinical Medicine 9:8, pages 2433.
Crossref
Yuan Fang, Guochao Liao & Bin Yu. (2019) LSD1/KDM1A inhibitors in clinical trials: advances and prospects. Journal of Hematology & Oncology 12:1.
Crossref
Helai P. Mohammad, Olena Barbash & Caretha L. Creasy. (2019) Targeting epigenetic modifications in cancer therapy: erasing the roadmap to cancer. Nature Medicine 25:3, pages 403-418.
Crossref
Sophia Doll, Florian Gnad & Matthias Mann. (2019) The Case for Proteomics and Phospho‐Proteomics in Personalized Cancer Medicine. PROTEOMICS – Clinical Applications 13:2, pages 1800113.
Crossref
Augustine Ochen, Robert Whitten, Helen E. Aylott, Katie Ruffell, Glynn D. Williams, Fiona Slater, Andrew Roberts, Paul Evans, Janelle E. Steves & Mahesh J. Sanganee. (2018) Development of a Large-Scale Copper(I)/TEMPO-Catalyzed Aerobic Alcohol Oxidation for the Synthesis of LSD1 Inhibitor GSK2879552. Organometallics 38:1, pages 176-184.
Crossref
D. Prabavathy & Niveditha Ramadoss. 2019. Stem Cells Heterogeneity in Cancer. Stem Cells Heterogeneity in Cancer 41 57 .
Michelle L. Duquette, Justine Kim, Linda Z. Shi & Michael W. Berns. (2018) LSD1 mediated changes in the local redox environment during the DNA damage response. PLOS ONE 13:8, pages e0201907.
Crossref
Sophia Doll, Maximilian C. Kriegmair, Alberto Santos, Michael Wierer, Fabian Coscia, Helen Michele Neil, Stefan Porubsky, Philipp E. Geyer, Andreas Mund, Philipp Nuhn & Matthias Mann. (2018) Rapid proteomic analysis for solid tumors reveals LSD 1 as a drug target in an end‐stage cancer patient . Molecular Oncology 12:8, pages 1296-1307.
Crossref
Chin Soon Chee & Danny Leung. (2018) Targeting Epigenetic Modifiers for Cancer Treatments. Current Pharmacology Reports 4:3, pages 193-201.
Crossref
Anu Prakash, Juan Garcia-Moreno, James Brown & Emer Bourke. (2018) Clinically Applicable Inhibitors Impacting Genome Stability. Molecules 23:5, pages 1166.
Crossref
Adi F. Gazdar, Paul A. Bunn & John D. Minna. (2017) Small-cell lung cancer: what we know, what we need to know and the path forward. Nature Reviews Cancer 17:12, pages 725-737.
Crossref
Tinka Haydn, Eric Metzger, Roland Schuele & Simone Fulda. (2017) Concomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells. Cell Death & Disease 8:6, pages e2879-e2879.
Crossref
Jiang Chen, Jie Ding, Ziwei Wang, Jian Zhu, Xuejian Wang & Jiyi Du. (2017) Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells. Oncotarget 8:12, pages 19609-19630.
Crossref
Wen Fong Ooi, Xiaosai Yao, Patrick Tan & Bin Tean Teh. 2017. DNA and Histone Methylation as Cancer Targets. DNA and Histone Methylation as Cancer Targets 221 248 .
Chiharu Uchida. (2016) Roles of pRB in the Regulation of Nucleosome and Chromatin Structures. BioMed Research International 2016, pages 1-11.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.