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Journal of Environmental Science and Health, Part C
Toxicology and Carcinogenesis
Volume 39, 2021 - Issue 1
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Articles

Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity

Si Chena Division of Biochemical Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USAORCID Iconhttps://orcid.org/0000-0002-8872-311X
ORCID Icon,
Qiangen Wua Division of Biochemical Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USA
,
Xilin Lib Division of Genetic and Molecular Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USA
,
Dongying Lic Division of Bioinformatics and Biostatistics, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USAORCID Iconhttps://orcid.org/0000-0003-0721-2500
ORCID Icon,
Nan Meib Division of Genetic and Molecular Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USAORCID Iconhttps://orcid.org/0000-0002-3501-9014
ORCID Icon,
Baitang Ningc Division of Bioinformatics and Biostatistics, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USA
,
Montserrat Puigd Division of Biotechnology Review and Research III, Office of Biotechnology Products, Center for Drug Evaluation and Research/U.S. FDA, Silver Spring, Maryland, USA
,
Zhen Rena Division of Biochemical Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USA
,
William H. Tollesona Division of Biochemical Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USA
&
Lei Guoa Division of Biochemical Toxicology, National Center for Toxicological Research/U.S. FDA, Jefferson, Arkansas, USACorrespondence[email protected]
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Pages 68-86 | Published online: 12 Feb 2021

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Xilin Li, Yuxi Li, Kylie G. Ning, Si Chen, Lei Guo, Jessica A. Bonzo & Nan Mei. (2022) The expression of Phase II drug-metabolizing enzymes in human B-lymphoblastoid TK6 cells. Journal of Environmental Science and Health, Part C 40:1, pages 106-118.
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Han Li, Yu-Guang Wang, Zeng-Chun Ma, Gao Yun-Hang, Song Ling, Chen Teng-Fei, Zhang Guang-Ping & Yue Gao. (2021) A high-throughput cell-based gaussia luciferase reporter assay for measurement of CYP1A1, CYP2B6, and CYP3A4 induction. Xenobiotica 51:7, pages 752-763.
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