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Original Articles

Maternal Smoking During Pregnancy and Child Outcomes: Real or Spurious Effect?

Pages 1-36 | Published online: 23 Jan 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Matias Vaajala, Jeremias Tarkiainen, Rasmus Liukkonen, Ilari Kuitunen, Ville Ponkilainen, Maiju Kekki & Ville M. Mattila. (2023) Traumatic brain injury during pregnancy is associated with increased rate of cesarean section: a nationwide multi-register study in Finland. The Journal of Maternal-Fetal & Neonatal Medicine 36:1.
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Matias Vaajala, Rasmus Liukkonen, Ville Ponkilainen, Maiju Kekki, Ville M. Mattila & Ilari Kuitunen. (2023) Delivery mode and fetal outcome in attempted vaginal deliveries after previous cesarean section: a nationwide register-based cohort study in Finland. The Journal of Maternal-Fetal & Neonatal Medicine 36:1.
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Tahereh Sadeghiyeh, Seyed Alireza Dastgheib, Mohamad Hosein Lookzadeh, Mahmood Noori-Shadkam, Mohammad Javad Akbarian-Bafghi, Masoud Zare-Shehneh, Zahra Poursharif & Hossein Neamatzadeh. (2020) Association of MTHFR 677C > T and 1298A > C polymorphisms with susceptibility to attention deficit and hyperactivity disorder. Fetal and Pediatric Pathology 39:5, pages 422-429.
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Anja C Huizink & Susan M Bögels. (2013) Moving beyond the Longitudinal Approach to Understand Prenatal Mechanisms. Australian Psychologist 48:4, pages 246-248.
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Articles from other publishers (177)

Leonardo A. Ortega, Diana M. Aragon-Carvajal, Karen T. Cortes-Corso & Felipe Forero-Castillo. (2024) Early developmental risks for tobacco addiction: A probabilistic epigenesis framework. Neuroscience & Biobehavioral Reviews 156, pages 105499.
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Tursun Alkam, Ryan Shota & Toshitaka Nabeshima. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 777 788 .
Jane W. Y. Ng, Janine F. Felix & David M. Olson. (2023) A novel approach to risk exposure and epigenetics—the use of multidimensional context to gain insights into the early origins of cardiometabolic and neurocognitive health. BMC Medicine 21:1.
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M. Vaajala, M. Kekki, V.M. Mattila & I. Kuitunen. (2023) The association between epidural labor analgesia and the fetal outcome and mode of delivery of the second twin: a nationwide register-based cohort study in Finland. International Journal of Obstetric Anesthesia 56, pages 103924.
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Sarah E. Maylott, Elisabeth Conradt, Monica McGrath, Emily A. Knapp, Xiuhong Li, Rashelle Musci, Judy Aschner, Lyndsay A. Avalos, Lisa A. Croen, Sean Deoni, Karen Derefinko, Amy Elliott, Julie A. Hofheimer, Leslie D. Leve, Juliette C. Madan, Maxwell Mansolf, Liza B. Murrison, Jenae M. Neiderhiser, Sally Ozonoff, Jonathan Posner, Amy Salisbury, Sheela Sathyanarayana, Julie B. Schweitzer, Carl Seashore, Meagan E. Stabler, Leslie W. Young, Steven J. Ondersma, Barry Lester, P.B. Smith, K.L. Newby, L.P. Jacobson, C.B. Parker, R. Gershon, D. Cella, F.P. Perera, J.B. Herbstman, M.R. Karagas, J. Ganiban, A. Ferrara, L.A. Croen, N. Paneth, J.M. Kerver, D.M. Ruden, S. Deoni, V.A. D’Sa, C. Blair, J.M. Neiderhiser, K.Z. LeWinn, N.R. Bush, D. Dabelea, M. O'Shea, R. Fry, L.D. Leve, A. Mason, J.B. Stanford, A. Giardino, C.A. Porucznik, C. Karr, S. Sathyanarayana, J. Gern, A.J. Elliott, I. Hertz-Picciotto, J.B. Schweitzer & D. Bennett. (2023) Latent Class Analysis of Prenatal Substance Exposure and Child Behavioral Outcomes. The Journal of Pediatrics 260, pages 113468.
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Bernard F. Fuemmeler, Trevin E. Glasgow, Julia C. Schechter, Rachel Maguire, Yaou Sheng, Tatyana Bidopia, D. Jeremy Barsell, Albert Ksinan, Junfeng Zhang, Yan Lin, Cathrine Hoyo, Susan Murphy, Jian Qin, Xiangtian Wang & Scott Kollins. (2023) Prenatal and Childhood Smoke Exposure Associations with Cognition, Language, and Attention-Deficit/Hyperactivity Disorder. The Journal of Pediatrics 256, pages 77-84.e1.
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Hanna P. Wallin, Mika Gissler, Päivi E. Korhonen & Mikael O. Ekblad. (2022) New insights into smoking and urinary tract infections during pregnancy using pregnancy‐pair design: A population‐based register study. Acta Obstetricia et Gynecologica Scandinavica 102:1, pages 25-32.
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Chad Lance Hemady, Lydia Gabriela Speyer, Aja Louise Murray, Ruth Harriet Brown, Franziska Meinck, Deborah Fry, Huyen Do, Siham Sikander, Bernadette Madrid, Asvini Fernando, Susan Walker, Michael Dunne, Sarah Foley, Claire Hughes, Joseph Osafo, Adriana Baban, Diana Taut, Catherine L. Ward, Vo Van Thang, Pasco Fearon, Mark Tomlinson, Sara Valdebenito & Manuel Eisner. (2022) Patterns of adverse childhood experiences and associations with prenatal substance use and poor infant outcomes in a multi-country cohort of mothers: a latent class analysis. BMC Pregnancy and Childbirth 22:1.
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Valerie S. Knopik, Lauren Micalizzi, Kristine Marceau, Amy M. Loviska, Li Yu, Alexandra Bien, Emily Rolan, Allison S. Evans, Rohan H. C. Palmer & Andrew C. Heath. (2022) The roles of familial transmission and smoking during pregnancy on executive function skills: A sibling-comparison study. Development and Psychopathology, pages 1-13.
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Runyu Zou, Olga D. Boer, Janine F. Felix, Ryan L. Muetzel, Ingmar H. A. Franken, Charlotte A. M. Cecil & Hanan El Marroun. (2022) Association of Maternal Tobacco Use During Pregnancy With Preadolescent Brain Morphology Among Offspring. JAMA Network Open 5:8, pages e2224701.
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Ross Brannigan, Antti Tanskanen, Matti O. Huttunen, Mary Cannon, Finbarr P. Leacy & Mary C. Clarke. (2021) Maternal smoking during pregnancy and offspring psychiatric disorder: a longitudinal birth cohort study. Social Psychiatry and Psychiatric Epidemiology 57:3, pages 595-600.
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Christopher R. Beam, Alice J. Kim & Tinca J.C. Polderman. 2022. Twin Research for Everyone. Twin Research for Everyone 215 234 .
A OCHOZKOVÁ, L MIHALČÍKOVÁ, A YAMAMOTOVÁ & R ŠLAMBEROVÁ. (2021) Can Prenatal Methamphetamine Exposure be Considered a Good Animal Model for ADHD?. Physiological Research, pages S431-S440.
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Richard Xu, Xiumei Hong, Boyang Zhang, Wanyu Huang, Wenpin Hou, Guoying Wang, Xiaobin Wang, Tak Igusa, Liming Liang & Hongkai Ji. (2021) DNA methylation mediates the effect of maternal smoking on offspring birthweight: a birth cohort study of multi-ethnic US mother–newborn pairs. Clinical Epigenetics 13:1.
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Nikoletta R. Czobor, Zsófia Ocsovszky, György Roth, Szabolcs Takács, Márta Csabai, Edgár Székely, János Gál, Andrea Székely & Barna Konkolÿ Thege. (2021) ADHD symptomatology of children with congenital heart disease 10 years after cardiac surgery: the role of age at operation. BMC Psychiatry 21:1.
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Mikael O. Ekblad, Hanna P. Wallin, Marjukka Pajulo & Päivi E. Korhonen. (2021) Design of a prospective follow-up study on early parenthood and smoking behaviour during pregnancy in Finnish primary healthcare. Scandinavian Journal of Public Health 49:8, pages 970-980.
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Gabriela A. Barber & Edmond D. Shenassa. (2021) Smoking status: A tacit screen for postpartum depression in primary care settings. Journal of Affective Disorders 295, pages 1243-1250.
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Getinet Ayano, Kim Betts, Berihun Assefa Dachew & Rosa Alati. (2021) Maternal smoking during pregnancy and poor academic performance in adolescent offspring: A registry data-based cohort study. Addictive Behaviors 123, pages 107072.
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Suena H. Massey, Norrina B. Allen, Lindsay R. Pool, Emily S. Miller, Nicole R. Pouppirt, Deanna M. Barch, Joan Luby, Susan B. Perlman, Cynthia E. Rogers, Chris D. Smyser & Lauren S. Wakschlag. (2021) Impact of prenatal exposure characterization on early risk detection: Methodologic insights for the HEALthy Brain and Child Development (HBCD) study. Neurotoxicology and Teratology 88, pages 107035.
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Jordan M. Buck, Heidi C. O’Neill & Jerry A. Stitzel. (2021) The Intergenerational Transmission of Developmental Nicotine Exposure-Induced Neurodevelopmental Disorder-Like Phenotypes is Modulated by the Chrna5 D397N Polymorphism in Adolescent Mice. Behavior Genetics 51:6, pages 665-684.
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Farah Naja, Jennifer Ayoub, Samar Baydoun, Sahar Nassour, Pamela Zgheib & Lara Nasreddine. (2021) Development of national dietary and lifestyle guidelines for pregnant women in Lebanon. Maternal & Child Nutrition 17:4.
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Neda Mortaji, John E Krzeczkowski, Khrista Boylan, Linda Booij, Maude Perreault & Ryan J Van Lieshout. (2021) Maternal pregnancy diet, postnatal home environment and executive function and behavior in 3- to 4-y-olds. The American Journal of Clinical Nutrition 114:4, pages 1418-1427.
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Tadashi Shiohama, Aya Hisada, Midori Yamamoto, Kenichi Sakurai, Rieko Takatani, Katsunori Fujii, Naoki Shimojo, Chisato Mori, Michihiro Kamijima, Shin Yamazaki, Yukihiro Ohya, Reiko Kishi, Nobuo Yaegashi, Koichi Hashimoto, Chisato Mori, Shuichi Ito, Zentaro Yamagata, Hidekuni Inadera, Takeo Nakayama, Hiroyasu Iso, Masayuki Shima, Youichi Kurozawa, Narufumi Suganuma, Koichi Kusuhara & Takahiko Katoh. (2021) Decreased head circumference at birth associated with maternal tobacco smoke exposure during pregnancy on the Japanese prospective birth cohort study. Scientific Reports 11:1.
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Jordan M Buck, Li Yu, Valerie S Knopik & Jerry A Stitzel. (2021) DNA methylome perturbations: an epigenetic basis for the emergingly heritable neurodevelopmental abnormalities associated with maternal smoking and maternal nicotine exposure. Biology of Reproduction 105:3, pages 644-666.
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C.C. Paccola, G.S. Souza, I.M.M. Freitas, J.C. Souza, L.L. Martins, V. Vendramini & S.M. Miraglia. (2021) Does maternal exposure to nicotine affect the oocyte quality and reproductive capacity in adult offspring?. Toxicology and Applied Pharmacology 426, pages 115638.
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Susanne V. Koch, Mikael Andersson, Carolina Hvelplund & Anne Mette Skovgaard. (2020) Mental disorders in referred 0–3-year-old children: a population-based study of incidence, comorbidity and perinatal risk factors. European Child & Adolescent Psychiatry 30:8, pages 1251-1262.
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Aurélie Nakamura, Olivier François & Johanna Lepeule. (2021) Epigenetic Alterations of Maternal Tobacco Smoking during Pregnancy: A Narrative Review. International Journal of Environmental Research and Public Health 18:10, pages 5083.
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Massimiliano Orri, Nicholas Chadi, Marilyn N. Ahun, Jean R. Seguin, Richard E. Tremblay, Michel Boivin, Gustavo Turecki, Marie-Claude Geoffroy & Sylvana M. Côté. (2021) Suicidal ideation and attempt in adolescents exposed to maternal smoking across pregnancy and childhood: A 20-year prospective cohort study. Journal of Affective Disorders 286, pages 10-18.
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Edmond D. Shenassa, Michelle L. Rogers & Stephen L. Buka. (2021) Maternal smoking during pregnancy, offspring smoking, adverse childhood events, and risk of major depression: a sibling design study. Psychological Medicine, pages 1-11.
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Lauren Micalizzi, Kristine Marceau, Allison S. Evans, Leslie A. Brick, Rohan H.C. Palmer, Andrew C. Heath & Valerie S. Knopik. (2021) A sibling-comparison study of smoking during pregnancy and risk for reading-related problems. Neurotoxicology and Teratology 84, pages 106961.
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Elizabeth W. Diemer, James I. Hudson & Kristin N. Javaras. (2021) More (Adjustment) Is Not Always Better: How Directed Acyclic Graphs Can Help Researchers Decide Which Covariates to Include in Models for the Causal Relationship between an Exposure and an Outcome in Observational Research. Psychotherapy and Psychosomatics 90:5, pages 289-298.
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Bereket Duko, Gavin Pereira, Kim Betts, Robert J. Tait, John Newnham & Rosa Alati. (2021) Prenatal alcohol and tobacco use and the risk of depression in offspring at age of 17 years: findings from the Raine Study. Journal of Affective Disorders 279, pages 426-433.
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Zsuzsánna Simon-Szabó, Enikő Nemes-Nagy, Lóránd Dénes & Béla Szabó. (2020) The Influence of Oxidative Stress-Related Factors on Pregnancy and Neonatal Outcomes. Journal of Interdisciplinary Medicine 5:4, pages 146-151.
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Shahrzad Nematollahi, Koroush Holakouie-Naieni, Abdolhossain Madani, Hossein Shabkhiz, Elham Torabi & Samane Lotfi. (2020) The effect of quitting water pipe during pregnancy on anthropometric measurements at birth: a population-based prospective cohort study in the south of Iran. BMC Pregnancy and Childbirth 20:1.
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Bereket Duko, Getinet Ayano, Gavin Pereira, Kim Betts & Rosa Alati. (2020) Prenatal tobacco use and the risk of mood disorders in offspring: a systematic review and meta-analysis. Social Psychiatry and Psychiatric Epidemiology 55:12, pages 1549-1562.
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Mikael O. Ekblad, Kristine Marceau, Emily Rolan, Rohan H. C. Palmer, Alexandre Todorov, Andrew C. Heath & Valerie S. Knopik. (2020) The Effect of Smoking during Pregnancy on Severity and Directionality of Externalizing and Internalizing Symptoms: A Genetically Informed Approach. International Journal of Environmental Research and Public Health 17:21, pages 7921.
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Yan He, Jian Chen, Li-Hua Zhu, Ling-Ling Hua & Fang-Fang Ke. (2017) Maternal Smoking During Pregnancy and ADHD: Results From a Systematic Review and Meta-Analysis of Prospective Cohort Studies. Journal of Attention Disorders 24:12, pages 1637-1647.
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Suena H. Massey, Caron A.C. Clark, Michael Y. Sun, James L. Burns, Daniel K. Mroczek, Kimberly A. Espy & Lauren S. Wakschlag. (2020) Dimension- and context-specific expression of preschoolers' disruptive behaviors associated with prenatal tobacco exposure. Neurotoxicology and Teratology 81, pages 106915.
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Mikael O Ekblad, Emily Rolan, Kristine Marceau, Rohan Palmer, Alexandre Todorov, Andrew C Heath & Valerie S Knopik. (2020) Disruptive Behavior in Siblings Discordant for Exposure to Maternal Smoking During Pregnancy: A Multi-rater Approach. Nicotine & Tobacco Research 22:8, pages 1330-1338.
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A. OCHOZKOVÁ, L. MIHALČÍKOVÁ, A. YAMAMOTOVÁ & R. ŠLAMBEROVÁ. (2019) ADHD Symptoms Induced by Prenatal Methamphetamine Exposure. Physiological Research, pages S347-S352.
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