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Microcirculation Volume 10, 2003 - Issue 5
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Research Article

Early Hepatic Microvascular Injury in Response to Acetaminophen Toxicity

YOSHIYA ITO Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, AZ, USA
,
NANCY W. BETHEA Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, AZ, USA
,
EDWARD R. ABRIL Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, AZ, USA
&
ROBERT S. MCCUSKEY Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, AZ, USA
Pages 391-400 | Published online: 10 Jul 2009

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Mitchell R. McGill & Jack A. Hinson. (2020) The development and hepatotoxicity of acetaminophen: reviewing over a century of progress. Drug Metabolism Reviews 52:4, pages 472-500.
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Tamiris Alves Rocha, Danielle Feijó de Moura, Marllyn Marques da Silva, Talita Giselly dos Santos Souza, Maria Aparecida da Conceição de Lira, Dayane de Melo Barros, Alexandre Gomes da Silva, Rafael Matos Ximenes, Emerson Peter da Silva Falcão, Cristiano Aparecido Chagas, Francisco Carlos Amanajás de Aguiar Júnior, Noêmia Pereira da Silva Santos, Marcia Vanusa da Silva & Maria Tereza dos Santos Correia. (2019) Evaluation of cytotoxic potential, oral toxicity, genotoxicity, and mutagenicity of organic extracts of Pityrocarpa moniliformis. Journal of Toxicology and Environmental Health, Part A 82:3, pages 216-231.
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Christa Y Watson, Ramon M Molina, Andressa Louzada, Kimberly M Murdaugh, Thomas C Donaghey & Joseph D Brain. (2015) Effects of zinc oxide nanoparticles on Kupffer cell phagosomal motility, bacterial clearance, and liver function. International Journal of Nanomedicine 10, pages 4173-4184.
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Edward L. LeCluyse, Rafal P. Witek, Melvin E. Andersen & Mark J. Powers. (2012) Organotypic liver culture models: Meeting current challenges in toxicity testing. Critical Reviews in Toxicology 42:6, pages 501-548.
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Hartmut Jaeschke, Mitchell R. McGill & Anup Ramachandran. (2012) Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity. Drug Metabolism Reviews 44:1, pages 88-106.
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Alison Hege Harrill & Ivan Rusyn. (2008) Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity. Expert Opinion on Drug Metabolism & Toxicology 4:11, pages 1379-1389.
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Dianne Botta, Collin C. White, Portia Vliet-Gregg, Isaac Mohar, Shengli Shi, Monica B. McGrath, Lisa A. McConnachie & Terrance J. Kavanagh. (2008) Modulating GSH Synthesis Using Glutamate Cysteine Ligase Transgenic and Gene-Targeted Mice. Drug Metabolism Reviews 40:3, pages 465-477.
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YOSHIYA ITO, EDWARD R. ABRIL, NANCY W. BETHEA, MARGARET K. MCCUSKEY & ROBERT S. MCCUSKEY. (2006) Dietary Steatotic Liver Attenuates Acetaminophen Hepatotoxicity in Mice. Microcirculation 13:1, pages 19-27.
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Hartmut Jaeschke. (2005) Role of inflammation in the mechanism of acetaminophen-induced hepatotoxicity. Expert Opinion on Drug Metabolism & Toxicology 1:3, pages 389-397.
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YOSHIYA ITO, EDWARD R. ABRIL, NANCY W. BETHEA & ROBERT S. MCCUSKEY. (2004) Ethanol Binging Enhances Hepatic Microvascular Responses to Acetaminophen in Mice. Microcirculation 11:7, pages 625-632.
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