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Journal of Biopharmaceutical Statistics Volume 11, 2001 - Issue 4
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Original Articles

COVARIATE-ADJUSTED RESPONSE-ADAPTIVE DESIGNS FOR BINARY RESPONSE

William F. Rosenberger Department of Mathematics and Statistics, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland, 21250, U.S.A.; Department of Epidemiology and preventative Medicine, University of Maryland School of Medicine, Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland, 21250, U.S.A.
,
A. N. Vidyashankar Department of Statistics, University of Georgia, Athens, Georgia, 30605, U.S.A.
&
Deepak K. Agarwal Department of Mathematics and Statistics, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland, 21250, U.S.A.
Pages 227-236 | Received 01 Jun 2000, Accepted 01 Sep 2001, Published online: 24 Jun 2011

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H. Jackson, S. Bowen & T. Jaki. (2023) Using biomarkers to allocate patients in a response-adaptive clinical trial. Communications in Statistics - Simulation and Computation 52:12, pages 5946-5965.
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Fengming Tang & Byron J. Gajewski. (2023) Comparative Effectiveness Research using Bayesian Adaptive Designs for Rare Diseases: Response Adaptive Randomization Reusing Participants. Statistics in Biopharmaceutical Research 15:1, pages 154-163.
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Atanu Biswas & Rahul Bhattacharya. (2018) A class of Covariate-Adjusted Response-Adaptive Allocation Designs for Multitreatment Binary Response Trials. Journal of Biopharmaceutical Statistics 28:5, pages 809-823.
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Yining Du, John D. Cook & J. Jack Lee. (2018) Comparing three regularization methods to avoid extreme allocation probability in response-adaptive randomization. Journal of Biopharmaceutical Statistics 28:2, pages 309-319.
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Atanu Biswas & Rahul Bhattacharya. (2016) A covariate-adjusted response-adaptive allocation for a general class of continuous responses. Journal of Statistical Theory and Practice 10:4, pages 852-863.
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Jianhua Hu, Hongjian Zhu & Feifang Hu. (2015) A Unified Family of Covariate-Adjusted Response-Adaptive Designs Based on Efficiency and Ethics. Journal of the American Statistical Association 110:509, pages 357-367.
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Oleksandr Sverdlov, WilliamF. Rosenberger & Yevgen Ryeznik. (2013) Utility of Covariate-Adjusted Response-Adaptive Randomization in Survival Trials. Statistics in Biopharmaceutical Research 5:1, pages 38-53.
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WilliamF. Rosenberger, Oleksandr Sverdlov & Feifang Hu. (2012) Adaptive Randomization for Clinical Trials. Journal of Biopharmaceutical Statistics 22:4, pages 719-736.
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GopalK. Basak, Atanu Biswas & Stanislav Volkov. (2009) An Urn Model for Odds-Ratio-Based Response-Adaptive Phase III Clinical Trials for Two or More Treatments. Journal of Biopharmaceutical Statistics 19:5, pages 838-856.
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Wasimul Bari & BrajendraC. Sutradhar. (2005) On binary longitudinal mixed models in adaptive clinical trials. Journal of Statistical Computation and Simulation 75:9, pages 687-707.
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Atanu Biswas & D. Stephen Coad. (2005) A General Multi-Treatment Adaptive Design for Multivariate Responses. Sequential Analysis 24:2, pages 139-158.
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Articles from other publishers (42)

David S. Robertson, Kim May Lee, Boryana C. López-Kolkovska & Sofía S. Villar. (2023) Response-Adaptive Randomization in Clinical Trials: From Myths to Practical Considerations. Statistical Science 38:2.
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Zhongqiang Liu & Xi Wang. (2023) Model-based adaptive randomization procedures for heteroscedasticity of treatment responses. Statistical Methods in Medical Research 32:7, pages 1361-1376.
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Ayon Mukherjee, D. Stephen Coad & Sayantee Jana. (2023) Covariate-adjusted response-adaptive designs for censored survival responses. Journal of Statistical Planning and Inference 225, pages 219-242.
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Hai Zhu & Hongjian Zhu. (2023) Covariate‐adjusted response‐adaptive designs based on semiparametric approaches. Biometrics.
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Soumyadeep Das, Rahul Bhattacharya & Atanu Biswas. (2022) Multi-arm covariate adjusted response adaptive designs for ordinal outcome clinical trials. Statistical Methods in Medical Research 32:1, pages 88-99.
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Yeonhee Park. (2022) Personalized Risk-Based Screening Design for Comparative Two-Arm Group Sequential Clinical Trials. Journal of Personalized Medicine 12:3, pages 448.
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Wanying Zhao, Wei Ma, Fan Wang & Feifang Hu. (2021) Incorporating covariates information in adaptive clinical trials for precision medicine. Pharmaceutical Statistics 21:1, pages 176-195.
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Hengtao Zhang & Guosheng Yin. (2021) Response-Adaptive Rerandomization. Journal of the Royal Statistical Society Series C: Applied Statistics 70:5, pages 1281-1298.
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Thomas Burnett, Pavel Mozgunov, Philip Pallmann, Sofia S. Villar, Graham M. Wheeler & Thomas Jaki. (2020) Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs. BMC Medicine 18:1.
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Selvakkadunko Selvaratnam, Yanqing Yi & Alwell Oyet. (2018) Maximum likelihood estimation of generalized linear models for adaptive designs: Applications and asymptotics. Biometrical Journal 61:3, pages 630-651.
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Giacomo Aletti, Andrea Ghiglietti & William F. Rosenberger. (2018) Nonparametric covariate-adjusted response-adaptive design based on a functional urn model. The Annals of Statistics 46:6B.
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Sofía S. VillarWilliam F. Rosenberger. (2018) Covariate-adjusted response-adaptive randomization for multi-arm clinical trials using a modified forward looking Gittins index rule. Biometrics 74:1, pages 49-57.
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Sofía S. Villar, Jack Bowden & James Wason. (2018) Response-adaptive designs for binary responses: How to offer patient benefit while being robust to time trends?. Pharmaceutical Statistics 17:2, pages 182-197.
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Selvakkadunko Selvaratnam, Alwell J. Oyet, Yanqing Yi & Veeresh Gadag. (2017) Estimation of a generalized linear mixed model for response-adaptive designs in multi-centre clinical trials. Canadian Journal of Statistics 45:3, pages 310-325.
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James E. Barrett. (2017) Information-adaptive clinical trials with selective recruitment and binary outcomes. Statistics in Medicine 36:18, pages 2803-2813.
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Eunsik Park & Yuan-chin Ivan Chang. (2016) Multiple-stage sampling procedure for covariate-adjusted response-adaptive designs. Statistical Methods in Medical Research 25:4, pages 1490-1511.
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William F. Rosenberger & John M. Lachin. 2016. Randomization in Clinical Trials. Randomization in Clinical Trials 189 216 .
Alessandro Baldi Antognini & Maroussa Zagoraiou. (2015) On the almost sure convergence of adaptive allocation procedures. Bernoulli 21:2.
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Feifang Hu, Yanqing Hu, Wei Ma, Lixin Zhang & Hongjian Zhu. (2015) Statistical inference of adaptive randomized clinical trials for personalized medicine. Clinical Investigation 5:4, pages 415-425.
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Yining Du, Xuan Wang & J. Jack Lee. (2015) Simulation study for evaluating the performance of response-adaptive randomization. Contemporary Clinical Trials 40, pages 15-25.
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D.Stephen Coad. 2014. Wiley StatsRef: Statistics Reference Online. Wiley StatsRef: Statistics Reference Online.
Jason S. TehranisaWilliam J. Meurer. (2014) Can Response-Adaptive Randomization Increase Participation in Acute Stroke Trials?. Stroke 45:7, pages 2131-2133.
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Siu Hung Cheung, Li-Xin Zhang, Feifang Hu & Wai Sum Chan. (2014) Covariate-adjusted response-adaptive designs for generalized linear models. Journal of Statistical Planning and Inference 149, pages 152-161.
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Antoine Chambaz & Mark J. van der Laan. (2014) Inference in Targeted Group-Sequential Covariate-Adjusted Randomized Clinical Trials. Scandinavian Journal of Statistics 41:1, pages 104-140.
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Uttam Bandyopadhyay & Rahul Bhattacharya. (2013) A covariate-adjusted response-adaptive allocation in clinical trials for a general class of responses. Statistics in Medicine 32:29, pages 5053-5061.
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Tao Huang, Zhongqiang Liu & Feifang Hu. (2013) Longitudinal covariate-adjusted response-adaptive randomized designs. Journal of Statistical Planning and Inference 143:10, pages 1816-1827.
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Hongjian Zhu, Feifang Hu & Hongyu Zhao. (2013) Adaptive clinical trial designs to detect interaction between treatment and a dichotomous biomarker. Canadian Journal of Statistics 41:3, pages 525-539.
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Atanu Biswas, Eunsik Park & Rahul Bhattacharya. (2010) Covariate-adjusted response-adaptive designs for longitudinal treatment responses: PEMF trial revisited. Statistical Methods in Medical Research 21:4, pages 379-392.
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Alessandro Baldi Antognini & Maroussa Zagoraiou. (2012) Multi-objective optimal designs in comparative clinical trials with covariates: The reinforced doubly adaptive biased coin design. The Annals of Statistics 40:3.
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Uttam BandyopadhyayRahul Bhattacharya. (2012) An urn based covariate adjusted response adaptive allocation design. Statistical Methods in Medical Research 21:2, pages 135-148.
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Xuemin Gu & J Jack Lee. (2010) A simulation study for comparing testing statistics in response-adaptive randomization. BMC Medical Research Methodology 10:1.
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Douglas P. Wiens. (2010) Robustness of design for the testing of lack of fit and for estimation in binary response models. Computational Statistics & Data Analysis 54:12, pages 3371-3378.
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Lanju Zhang & William Rosenberger. 2010. Handbook of Adaptive Designs in Pharmaceutical and Clinical Development. Handbook of Adaptive Designs in Pharmaceutical and Clinical Development 15-1 15-13 .
Jing Ning & Xuelin Huang. (2010) Response‐adaptive randomization for clinical trials with adjustment for covariate imbalance. Statistics in Medicine 29:17, pages 1761-1768.
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Shein-Chung ChowFeifang Hu & Anastasia Ivanova. 2010. Encyclopedia of Biopharmaceutical Statistics. Encyclopedia of Biopharmaceutical Statistics 1157 1161 .
Li-Xin Zhang & Fei-fang Hu. (2009) A new family of covariate-adjusted response adaptive designs and their properties. Applied Mathematics-A Journal of Chinese Universities 24:1, pages 1-13.
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D.Stephen Coad. 2007. Wiley Encyclopedia of Clinical Trials. Wiley Encyclopedia of Clinical Trials 1 7 .
Rahul Bhattacharya. (2008) Urn-Based Response Adaptive Procedures and Optimality. Drug Information Journal 42:5, pages 441-448.
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William F. Rosenberger & Oleksandr Sverdlov. (2008) Handling Covariates in the Design of Clinical Trials. Statistical Science 23:3.
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A.O. Ayanlowo & D.T. Redden. (2008) A two stage conditional power adaptive design adjusting for treatment by covariate interaction. Contemporary Clinical Trials 29:3, pages 428-438.
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Lanju Zhang & Atanu Biswas. (2007) Optimal Failure-Success Response-Adaptive Designs for Binary Responses. Drug Information Journal 41:6, pages 709-718.
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A. Lawrence Gould. (2006) How Practical are Adaptive Designs Likely to be for Confirmatory Trials?. Biometrical Journal 48:4, pages 644-649.
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