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Research Article

Sildenafil: Clinical Toxicology Profile

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Pages 645-651 | Published online: 20 Nov 2000

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Jun-Wei Chow, Ming-Ming Yan, Hui Zhao, Zi-Ran Li, Qian Zhang, Ming-Kang Zhong & Xiao-Yan Qiu. (2023) Skin cancer signal associated with phosphodiesterase inhibitors: gaining insight through the FDA pharmacovigilance database. Expert Opinion on Drug Safety 22:5, pages 433-441.
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Andrew Binder, Asghar Ali, Raveen Chawla, Hammad A Aziz, Antonio Abbate & Ion S Jovin. (2015) Myocardial protection from ischemia-reperfusion injury post coronary revascularization. Expert Review of Cardiovascular Therapy 13:9, pages 1045-1057.
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Brandon K. Wills, Charlotte Albinson, Michael Wahl & Jack Clifton. (2007) Sildenafil citrate ingestion and prolonged priapism and tachycardia in a pediatric patient. Clinical Toxicology 45:7, pages 798-800.
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Sharon Sze-Yin Oh, Peng Zou, Min-Yong Low & Hwee-Ling Koh. (2006) Detection of Sildenafil Analogues in Herbal Products for Erectile Dysfunction. Journal of Toxicology and Environmental Health, Part A 69:21, pages 1951-1958.
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MathiasB. Forrester & Leopoldo Artalejo$suffix/text()$suffix/text(). (2006) Pattern of Sildenafil Calls to Texas Poison Control Centers, 1998–2004. Journal of Toxicology and Environmental Health, Part A 69:6, pages 497-503.
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Alberto Briganti, Andrea Salonia, Andrea Gallina, Nazareno Suardi, Patrizio Rigatti & Francesco Montorsi. (2004) Emerging oral drugs for erectile dysfunction. Expert Opinion on Emerging Drugs 9:1, pages 179-189.
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Andrea Salonia, Patrizio Rigatti & Francesco Montorsi. (2003) Sildenafil in erectile dysfunction: a critical review. Current Medical Research and Opinion 19:4, pages 241-262.
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Dong-Zong Hung & Dar-Yu Yang. (2001) Sildenafil Overdose in a Female Patient. Journal of Toxicology: Clinical Toxicology 39:4, pages 423-424.
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Articles from other publishers (23)

Silvia L. Cruz. 2024. Encyclopedia of Toxicology. Encyclopedia of Toxicology 821 827 .
Raed Almannie, MeshariA Alzahrani, Mana Almuhaideb, Ibrahim Abunohaiah, Mohamad Habous & Saleh Binsaleh. (2023) Recreational use of oral erectile dysfunction medications among male physicians - A cross-sectional study. Urology Annals 15:2, pages 148.
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Rania Y. Mansour, Radwa ElBorolossy, Sara M. Shaheen & Nagwa A. Sabri. (2022) Evaluation of drug interactions of saxagliptin with sildenafil in healthy volunteers. European Journal of Clinical Pharmacology 78:12, pages 1935-1944.
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Mohammadsadegh Hamzehnejadi, Marziye Ranjbar Tavakoli, Ardavan Abiri, Ali Ghasempour, Mohammad Amin Langarizadeh & Hamid Forootanfar. (2022) A Review on Phosphodiesterase-5 Inhibitors as a Topical Therapy for Erectile Dysfunction. Sexual Medicine Reviews 10:3, pages 376-391.
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Abdoul Karim Sakira, Mitéhélé Sandrine Marie Josiane Ouattara, Moussa Yabre, Moumouni Bande & Touridomon Issa Some. (2021) Contribution to the Detection of Poor Quality Sildenafil Drugs in Burkina Faso Using High-Performance Thin-Layer Chromatography. Journal of Analytical Methods in Chemistry 2021, pages 1-9.
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Michael E. Mullins & Steven J. Fishburn. (2019) Comment on: “Drugs That Can Kill a Toddler with One Tablet or Teaspoonful: A 2018 Updated List”. Clinical Drug Investigation 39:8, pages 821-822.
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Mohammad AbdullaEyad MallahWael Abu DayyihWalid Abu RayyanFeras Darwish El-HajjiMona BustamiKenza MansourIsraa Al-AniNisreen SederTawfiq Arafat. (2018) Influence of Energy Drinks on Pharmacokinetic Parameters of Sildenafil in Rats. Biomedical and Pharmacology Journal 11:3, pages 1317-1328.
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DM Soares, FMM Ramos-Perez, SS Araújo, PG Correia Leite de Marcelos, AA Pontual & DEC Perez. (2018) Sildenafil citrate on experimental periodontitis in rats: Microtomographic and histological analyses. Oral Diseases 24:6, pages 1073-1082.
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Scott Bowen & Silvia L. Cruz. 2014. The Effects of Drug Abuse on the Human Nervous System. The Effects of Drug Abuse on the Human Nervous System 553 574 .
Faisal Mohamed Abou-Tarboush, Mohamed Fathy Abdel-Samad & Mokhlid Hamed Al-Meteri. (2011) Developmental toxicity of orally administered sildenafil citrate (Viagra) in SWR/J mice. Saudi Journal of Biological Sciences 18:2, pages 135-139.
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Faisal Mohamed Abou-Tarboush & Mohamed Fathy Abdel-Samad. (2010) Cytogenetic effects of sildenafil citrate (Viagra) on SWR/J mouse bone marrow cells. Saudi Journal of Biological Sciences 17:4, pages 315-319.
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T. Abdülkadir Coban, Şükrü Beydemir, İlhami Gücin, Deniz Ekinci, Alessio Innocenti, Daniela Vullo & Claudiu T. Supuran. (2009) Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I–XIV. Bioorganic & Medicinal Chemistry 17:16, pages 5791-5795.
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V Sekar, E Lefebvre, T De Marez, M De Pauw, E De Paepe, T Vangeneugden & R M W Hoetelmans. (2008) Effect of Repeated Doses of Darunavir plus Low-Dose Ritonavir on the Pharmacokinetics of Sildenafil in Healthy Male Subjects. Clinical Drug Investigation 28:8, pages 479-485.
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Gary Burgess, Hans Hoogkamer, Lorraine Collings & Jasper Dingemanse. (2007) Mutual pharmacokinetic interactions between steady-state bosentan and sildenafil. European Journal of Clinical Pharmacology 64:1, pages 43-50.
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Shahzad G. Raja, Mark D. Danton, Kenneth J. MacArthur & James C. Pollock. (2007) Effects of Escalating Doses of Sildenafil on Hemodynamics and Gas Exchange in Children With Pulmonary Hypertension and Congenital Cardiac Defects. Journal of Cardiothoracic and Vascular Anesthesia 21:2, pages 203-207.
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WILLIAM H. RICHARDSON, DAVID P. BETTEN, SARALYN R. WILLIAMS & RICHARD F. CLARK. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 983 999 .
Shahzad G. Raja, Mark D. Danton, Kenneth J. MacArthur & James C. Pollock. (2006) Treatment of Pulmonary Arterial Hypertension With Sildenafil: From Pathophysiology to Clinical Evidence. Journal of Cardiothoracic and Vascular Anesthesia 20:5, pages 722-735.
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C Lindsay DeVane. (2006) Antidepressant–Drug Interactions are Potentially but Rarely Clinically Significant. Neuropsychopharmacology 31:8, pages 1594-1604.
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Mohsen A. Hedaya, Dalia R. El-Afify & Gamal M. El-Maghraby. (2006) The effect of ciprofloxacin and clarithromycin on sildenafil oral bioavailability in human volunteers. Biopharmaceutics & Drug Disposition 27:2, pages 103-110.
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Alberto Briganti, Andrea Salonia, Federico Deho’, Giuseppe Zanni, Luigi Barbieri, Patrizio Rigatti & Francesco Montorsi. (2005) Clinical update on phosphodiesterase type-5 inhibitors for erectile dysfunction. World Journal of Urology 23:6, pages 374-384.
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M G??rhan Ulusoy, Af&OV0613;in Uysal, U??ur Ko??er, ??nder Karaaslan, S Sedat Cuzdan, Ali Ayyldz & H??seyin ??st??n. (2005) Improved Flap Viability With Site-Specific Delivery of Sildenafil Citrate Using Fibrin Glue. Annals of Plastic Surgery 55:3, pages 292-296.
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Alberto Briganti, Andrea Salonia, Andrea Gallina, Antonino Saccà, Piero Montorsi, Patrizio Rigatti & Francesco Montorsi. (2005) Drug Insight: oral phosphodiesterase type 5 inhibitors for erectile dysfunction. Nature Clinical Practice Urology 2:5, pages 239-247.
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JA McEniery, RG Delbridge & DM Reith. (2004) Infant pertussis deaths and the management of cardiovascular compromise. Journal of Paediatrics and Child Health 40:4, pages 230-232.
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