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Research Article

Insulin-Glucose as Adjunctive Therapy for Severe Calcium Channel Antagonist Poisoning

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Pages 463-474 | Published online: 16 Aug 1999

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Jon B. Cole, Samantha C. Lee, Matthew E. Prekker, Nathan M. Kunzler, Kelly A. Considine, Brian E. Driver, Michael A. Puskarich & Travis D. Olives. (2022) Vasodilation in patients with calcium channel blocker poisoning treated with high-dose insulin: a comparison of amlodipine versus non-dihydropyridines. Clinical Toxicology 60:11, pages 1205-1213.
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A. K. Pannu, A. Bhalla, J. Gantala, N. Sharma, S. Kumar & D. P. Dhibar. (2020) Glucose-insulin-potassium infusion for the treatment of acute aluminum phosphide poisoning: an open-label pilot study. Clinical Toxicology 58:10, pages 1004-1009.
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Katherine G. Katzung, Jenna M. Leroy, Sean P. Boley, Samuel J. Stellpflug, Joel S. Holger & Kristin M. Engebretsen. (2019) A randomized controlled study comparing high-dose insulin to vasopressors or combination therapy in a porcine model of refractory propranolol-induced cardiogenic shock. Clinical Toxicology 57:11, pages 1073-1079.
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Colin B. Page, Nicole M. Ryan & Geoffrey K. Isbister. (2018) The safety of high-dose insulin euglycaemia therapy in toxin-induced cardiac toxicity. Clinical Toxicology 56:6, pages 389-396.
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Michael E. Mullins & B. Zane Horowitz. (2017) In our experience. Toxicology Communications 1:1, pages 1-1.
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Dayne Laskey, Rajesh Vadlapatla & Katherine Hart. (2016) Stability of high-dose insulin in normal saline bags for treatment of calcium channel blocker and beta blocker overdose. Clinical Toxicology 54:9, pages 829-832.
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M. St-Onge, P.-A. Dubé, S. Gosselin, C. Guimont, J. Godwin, P. M. Archambault, J.-M. Chauny, A. J. Frenette, M. Darveau, N. Le sage, J. Poitras, J. Provencher, D. N. Juurlink & R. Blais. (2014) Treatment for calcium channel blocker poisoning: A systematic review. Clinical Toxicology 52:9, pages 926-944.
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Kristin M. Engebretsen, Kathleen M. Kaczmarek, Jenifer Morgan & Joel S. Holger. (2011) High-dose insulin therapy in beta-blocker and calcium channel-blocker poisoning. Clinical Toxicology 49:4, pages 277-283.
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Joel S. Holger, Kristin M. Engebretsen & John J. Marini. (2009) High dose insulin in toxic cardiogenic shock. Clinical Toxicology 47:4, pages 303-307.
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Silas W. Smith, Kathy L. Ferguson, Robert S. Hoffman, Lewis S. Nelson & Howard A. Greller. (2008) Prolonged severe hypotension following combined amlodipine and valsartan ingestion. Clinical Toxicology 46:5, pages 470-474.
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Andis Graudins, Javad Najafi & Michael Perry M. Rur-sc. (2008) Treatment of experimental verapamil poisoning with levosimendan utilizing a rodent model of drug toxicity. Clinical Toxicology 46:1, pages 50-56.
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Karthikeyan Kanagarajan, Jeanna M. Marraffa, Nicole C. Bouchard, Padmanabhan Krishnan, Robert S. Hoffman & Christine M. Stork. (2007) The use of vasopressin in the setting of recalcitrant hypotension due to calcium channel blocker overdose. Clinical Toxicology 45:1, pages 56-59.
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Kent R. Olson, Andrew R. Erdman, Alan D. Woolf, Elizabeth J. Scharman, Gwenn Christianson, E. Martin Caravati, Paul M. Wax, Lisa L. Booze, Anthony S. Manoguerra, Daniel C. Keyes, Peter A. Chyka & William G. Troutman. (2005) Calcium Channel Blocker Ingestion: An Evidence-Based Consensus Guideline for Out-of-Hospital Management. Clinical Toxicology 43:7, pages 797-822.
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Evan S. Schwarz. 2016. Critical Care Toxicology. Critical Care Toxicology 1 37 .
Kristin Engebretsen. 2016. Critical Care Toxicology. Critical Care Toxicology 1 10 .
Hallam Gugelmann & Neal Benowitz. 2016. Critical Care Toxicology. Critical Care Toxicology 1 34 .
Fang Lai, Yan Zhang, Dong-ping Xie, Fang Li & Yun Han. (2015) Successful treatment with integrated Chinese and western medicine for severe overdose of amlodipine: A case report. Chinese Journal of Integrative Medicine 21:9, pages 703-706.
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Crossref
RL Weinberg, NC Bouchard, DC Abrams, M Bacchetta, AL Dzierba, KM Burkart & D Brodie. (2013) Venoarterial extracorporeal membrane oxygenation for the management of massive amlodipine overdose. Perfusion 29:1, pages 53-56.
Crossref
Jeffrey A. Kline. (2014) Insulin for Calcium Channel Toxicity. Annals of Emergency Medicine 63:1, pages 92-93.
Crossref
Ajay Handa, Vimal Upreti, V. R. Ratheesh & Pawan Dhull. (2013) Shock due to amlodipine overdose. Indian Journal of Critical Care Medicine 17:6, pages 375-377.
Crossref
Sruti R. Patel. (2013) Toxicologic Emergencies in the Intensive Care Unit. Critical Care Nursing Quarterly 36:4, pages 335-344.
Crossref
Michael Levine, Steven C. Curry, Angela Padilla-Jones & Anne-Michelle Ruha. (2013) Critical Care Management ofVerapamil and Diltiazem Overdose With a Focus on Vasopressors: A 25-Year Experience at a Single Center. Annals of Emergency Medicine 62:3, pages 252-258.
Crossref
Shrinivas Kambali, Raed Alalawi & Kenneth Nugent. (2013) Prolonged Refractory Hypotension Secondary to Amlodipine Overdose. ICU Director 4:3, pages 136-142.
Crossref
Kirk L. Cumpston. 2013. Emergency Medicine. Emergency Medicine 1266 1279.e1 .
Ilona Šuškevičienė, Tomas Bukauskas, Linas Pieteris, Giedrė Bakšytė & Andrius Macas. (2012) Antiaritmikų perdozavimas: efektyvi gydytojo pagalbaOverdose of Antiarrhytmic Drugs: Efective Medical Assistance. Sveikatos mokslai 22:5, pages 146-152.
Crossref
Henry A. Spiller, Beth A. Milliner & George M. Bosse. (2012) Amlodipine Fatality in an Infant with Postmortem Blood Levels. Journal of Medical Toxicology 8:2, pages 179-182.
Crossref
Ian Whyte, Nick Buckley & Andrew Dawson. (2012) Calcium channel blockers. Medicine 40:3, pages 112-114.
Crossref
Cristine L. Hayes & Michael Knight. (2012) Calcium Channel Blocker Toxicity in Dogs and Cats. Veterinary Clinics of North America: Small Animal Practice 42:2, pages 263-277.
Crossref
Jeanna M. MarraffaVictor CohenMary Ann Howland. (2012) Antidotes for toxicological emergencies: A practical review. American Journal of Health-System Pharmacy 69:3, pages 199-212.
Crossref
Shiwan K. Shah, Sanjeev Kumar Goswami, Rajesh V. Babu, Gulshan Sharma & Alexander G. Duarte. (2012) Management of Calcium Channel Antagonist Overdose with Hyperinsulinemia-Euglycemia Therapy: Case Series and Review of the Literature. Case Reports in Critical Care 2012, pages 1-5.
Crossref
Melissa L. Givens. (2012) Toxic Bradycardias in the Critically Ill Poisoned Patient. Emergency Medicine International 2012, pages 1-6.
Crossref
Eric Perez, Jason Chu, Theodore Bania & Kamal Medlej. (2011) l-Carnitine Increases Survival in a Murine Model of Severe Verapamil Toxicity. Academic Emergency Medicine 18:11, pages 1135-1140.
Crossref
Victor Cohen, Samantha P. Jellinek, Lydia Fancher, Geetanjli Sangwan, Menachem Wakslak, Elizabeth Marquart & Cyrus Farahani. (2011) Tarka® (Trandolapril/Verapamil Hydrochloride Extended-Release) overdose. The Journal of Emergency Medicine 40:3, pages 291-295.
Crossref
Daniel E. Brooks & Kenneth D. Katz. 2011. Textbook of Critical Care. Textbook of Critical Care 1291 1293 .
Lindsay Murray, Frank Daly, Mark Little & Mike Cadogan. 2011. Toxicology Handbook. Toxicology Handbook 371 428 .
Lindsay Murray, Frank Daly, Mark Little & Mike Cadogan. 2011. Toxicology Handbook. Toxicology Handbook 127 370 .
Ashley N. Webb & Prashant Joshi. 2011. Pediatric Critical Care. Pediatric Critical Care 1451 1462 .
Jennie A. Buchanan. 2011. Emergency Medicine Secrets. Emergency Medicine Secrets 524 528 .
Monica E. Kleinman, Leon Chameides, Stephen M. Schexnayder, Ricardo A. Samson, Mary Fran Hazinski, Dianne L. Atkins, Marc D. Berg, Allan R. de Caen, Ericka L. Fink, Eugene B. Freid, Robert W. Hickey, Bradley S. Marino, Vinay M. Nadkarni, Lester T. Proctor, Faiqa A. Qureshi, Kennith Sartorelli, Alexis Topjian, Elise W. van der Jagt & Arno L. Zaritsky. (2010) Part 14: Pediatric Advanced Life Support. Circulation 122:18_suppl_3.
Crossref
Terry L. Vanden Hoek, Laurie J. Morrison, Michael Shuster, Michael Donnino, Elizabeth Sinz, Eric J. Lavonas, Farida M. Jeejeebhoy & Andrea Gabrielli. (2010) Part 12: Cardiac Arrest in Special Situations. Circulation 122:18_suppl_3.
Crossref
J. Soar, G.D. Perkins, G. Abbas, A. Alfonzo, A. Barelli, J.J.L.M. Bierens, H. Brugger, C.D. Deakin, J. Dunning, M. Georgiou, A.J. Handley, D.J. Lockey, P. Paal, C. Sandroni, K.-C. Thies, D.A. Zideman & J.P. Nolan. (2010) Kreislaufstillstand unter besonderen Umständen: Elektrolytstörungen, Vergiftungen, Ertrinken, Unterkühlung, Hitzekrankheit, Asthma, Anaphylaxie, Herzchirurgie, Trauma, Schwangerschaft, Stromunfall. Notfall + Rettungsmedizin 13:7, pages 679-722.
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Crossref
Charles D. Deakin, Laurie J. Morrison, Peter T. Morley, Clifton W. Callaway, Richard E. Kerber, Steven L. Kronick, Eric J. Lavonas, Mark S. Link, Robert W. Neumar, Charles W. Otto, Michael Parr, Michael Shuster, Kjetil Sunde, Mary Ann Peberdy, Wanchun Tang, Terry L. Vanden Hoek, Bernd W. Böttiger, Saul Drajer, Swee Han Lim & Jerry P. Nolan. (2010) Part 8: Advanced life support. Resuscitation 81:1, pages e93-e174.
Crossref
Jasmeet Soar, Gavin D. Perkins, Gamal Abbas, Annette Alfonzo, Alessandro Barelli, Joost J.L.M. Bierens, Hermann Brugger, Charles D. Deakin, Joel Dunning, Marios Georgiou, Anthony J. Handley, David J. Lockey, Peter Paal, Claudio Sandroni, Karl-Christian Thies, David A. Zideman & Jerry P. Nolan. (2010) European Resuscitation Council Guidelines for Resuscitation 2010 Section 8. Cardiac arrest in special circumstances: Electrolyte abnormalities, poisoning, drowning, accidental hypothermia, hyperthermia, asthma, anaphylaxis, cardiac surgery, trauma, pregnancy, electrocution. Resuscitation 81:10, pages 1400-1433.
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Larry L. Louters, Nathan Stehouwer, Janelle Rekman, Andrew Tidball, Alexandra Cok & Christopher P. Holstege. (2010) Verapamil Inhibits the Glucose Transport Activity of GLUT1. Journal of Medical Toxicology 6:2, pages 100-105.
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Michael J. Lynch, Kenneth D. Katz, Clifton W. Callaway & Eric S. Logue. (2010) Survival of Verapamil-Poisoned Rats Treated with Triiodothyronine. Journal of Medical Toxicology 6:2, pages 94-99.
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Brandon K. Wills, J. Marc Liu & Michael Wahl. (2010) Third-Degree AV Block from Extended-Release Diltiazem Ingestion in a Nine-Month-Old. The Journal of Emergency Medicine 38:3, pages 328-331.
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Craig G. Smollin. (2010) Toxicology: Pearls and Pitfalls in the Use of Antidotes. Emergency Medicine Clinics of North America 28:1, pages 149-161.
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Mirjam Osthoff, Christine Bernsmeier, Stephan C. Marsch & Patrick R. Hunziker. (2010) Levosimendan as Treatment Option in Severe Verapamil Intoxication: A Case Report and Review of the Literature. Case Reports in Medicine 2010, pages 1-3.
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Hicham Azendour, L. Belyamani, M. Atmani, H. Balkhi & C. Haimeur. (2010) Severe Amlodipine Intoxication Treated by Hyperinsulinemia Euglycemia Therapy. The Journal of Emergency Medicine 38:1, pages 33-35.
Crossref
Megan DeMott, Michael Young, Saralyn R. Williams & Richard F. Clark. 2010. Cardiac Intensive Care. Cardiac Intensive Care 427 442 .
David J. Roberts. 2010. Rosen's Emergency Medicine – Concepts and Clinical Practice. Rosen's Emergency Medicine – Concepts and Clinical Practice 1978 1988 .
Christopher P NicksonMark Little. (2009) Early use of high‐dose insulin euglycaemic therapy for verapamil toxicity. Medical Journal of Australia 191:6, pages 350-352.
Crossref
Tero Varpula, Janne Rapola, Marko Sallisalmi & Jouni Kurola. (2009) Levosimendan for Calcium Channel Blocker Poisoning in Humans. Anesthesia & Analgesia 109:3, pages 992-993.
Crossref
Tamara R. Espinoza, Allan R. Mottram & Sean M. Bryant. (2009) Levosimendan for Calcium Channel Blocker Poisoning in Humans. Anesthesia & Analgesia 109:3, pages 992.
Crossref
N. Deye, B. Mégarbane & F. Baud. 2009. Insuffisance circulatoire aiguë. Insuffisance circulatoire aiguë 549 588 .
Usama A. Hanhan. (2008) The Poisoned Child in the Pediatric Intensive Care Unit. Pediatric Clinics of North America 55:3, pages 669-686.
Crossref
Philip M. Alapat & Janice L. Zimmerman. (2008) Toxicology in the Critical Care Unit. Chest 133:4, pages 1006-1013.
Crossref
Christian Ezidiegwu, Zhanna Spektor, Michel R Nasr, Karen C Kelly & Lazaro G Rosales. (2008) A Case Report on the Role of Plasma Exchange in the Management of a Massive Amlodipine Besylate Intoxication. Therapeutic Apheresis and Dialysis 12:2, pages 180-184.
Crossref
John C. Chatham, Laszlo G. Nöt, Norbert Fülöp & Richard B. Marchase. (2008) HEXOSAMINE BIOSYNTHESIS AND PROTEIN O-GLYCOSYLATION. Shock 29:4, pages 431-440.
Crossref
Merilee Costello & Rebecca S. Syring. (2008) Calcium channel blocker toxicity. Journal of Veterinary Emergency and Critical Care 18:1, pages 54-60.
Crossref
Teresa J. Coco & Erica L. Liebelt. 2008. Pediatric Emergency Medicine. Pediatric Emergency Medicine 106 114 .
Nick Buckley, Andrew Dawson & Ian Whyte. (2007) Calcium channel blockers. Medicine 35:11, pages 599-602.
Crossref
Shaun L. Greene, Indika Gawarammana, David M. Wood, Alison L. Jones & Paul I. Dargan. (2007) Relative safety of hyperinsulinaemia/euglycaemia therapy in the management of calcium channel blocker overdose: a prospective observational study. Intensive Care Medicine 33:11, pages 2019-2024.
Crossref
Nirav P. PatelMeredith E. PughSteven GoldbergGlenn Eiger. (2007) Hyperinsulinemic Euglycemia Therapy for Verapamil Poisoning: Case Report. American Journal of Critical Care 16:5, pages 520-518.
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Nirav P. PatelMeredith E. PughSteven GoldbergGlenn Eiger. (2007) Hyperinsulinemic Euglycemia Therapy for Verapamil Poisoning: A Review. American Journal of Critical Care 16:5, pages 498-503.
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Mark B. Mycyk & Sean M. Bryant. (2007) Is simple bedside glucose assessment prognostic in calcium channel blocker overdose?*. Critical Care Medicine 35:9, pages 2216-2217.
Crossref
Claudia Ranniger & Colleen Roche. (2007) Are One or Two Dangerous? Calcium Channel Blocker Exposure in Toddlers. The Journal of Emergency Medicine 33:2, pages 145-154.
Crossref
Timothy B. Erickson, Trevonne M. Thompson & Jenny J. Lu. (2007) The Approach to the Patient with an Unknown Overdose. Emergency Medicine Clinics of North America 25:2, pages 249-281.
Crossref
William KernsIIII. (2007) Management of β-Adrenergic Blocker and Calcium Channel Antagonist Toxicity. Emergency Medicine Clinics of North America 25:2, pages 309-331.
Crossref
HT Fung, CH Lai, OF Wong, KK Lam & CW Kam. (2017) The Use of Glucagon and other Antidotes in a Case of Beta-Blocker and Calcium Channel Blocker Overdose. Hong Kong Journal of Emergency Medicine 14:2, pages 113-118.
Crossref
STEVEN D. SALHANICK. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 963 974 .
NANCY G. MURPHY, NEAL L. BENOWITZ & NORA GOLDSCHLAGER. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 133 165 .
Christian Tomaszewski. (2006) The power of the case report. Journal of Medical Toxicology 2:4, pages 139-140.
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René Panduro Poggenborg, Lars Videbæk & Ib Abildgaard Jacobsen. (2006) A Case of Amlodipine Overdose. Basic & Clinical Pharmacology & Toxicology 99:3, pages 209-212.
Crossref
Susanne Vogt, Annekathrin Mehlig, Patrick Hunziker, André Scholer, Julia Jung, Ana Baranda González, Wolfgang Weinmann & Stephan Marsch. (2006) Survival of severe amlodipine intoxication due to medical intensive care. Forensic Science International 161:2-3, pages 216-220.
Crossref
N. Stuart Harris. (2006) Case 24-2006. New England Journal of Medicine 355:6, pages 602-611.
Crossref
Diane P. Calello, Kevin C. Osterhoudt & Fred M. Henretig. (2006) New and Novel Antidotes in Pediatrics. Pediatric Emergency Care 22:7, pages 523-530.
Crossref
S. Eliza Halcomb & Lewis S. Nelson. (2006) Case files of the medical toxicology fellowship training program at the New York City Poison Control Center: Hypotensive death — Therapeutic complication or suicide?. Journal of Medical Toxicology 2:2, pages 75-80.
Crossref
. (2006) 2005 American Heart Association (AHA) Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care (ECC) of Pediatric and Neonatal Patients: Pediatric Advanced Life Support. Pediatrics 117:5, pages e1005-e1028.
Crossref
Keith Henry & Carson R. Harris. (2006) Deadly Ingestions. Pediatric Clinics of North America 53:2, pages 293-315.
Crossref
Simon Tebbutt, Martyn Harvey, Tonia Nicholson & Grant Cave. (2008) Intralipid Prolongs Survival in a Rat Model of Verapamil Toxicity. Academic Emergency Medicine 13:2, pages 134-139.
Crossref
Simon Tebbutt, Martyn Harvey, Tonia Nicholson & Grant Cave. (2006) Intralipid Prolongs Survival in a Rat Model of Verapamil Toxicity. Academic Emergency Medicine 13:2, pages 134-139.
Crossref
Tal Hasin, David Leibowitz, Meir Antopolsky & Tova Chajek-Shaul. (2006) The Use of Low-Dose Insulin in Cardiogenic Shock due to Combined Overdose of <i>Verapamil</i>, <i>Enalapril</i> and <i>Metoprolol</i>. Cardiology 106:4, pages 233-236.
Crossref
Prashant Joshi. 2006. Pediatric Critical Care. Pediatric Critical Care 1521 1531 .
. (2005) Part 12: Pediatric Advanced Life Support. Circulation 112:24_supplement.
Crossref
J Dave Barry. (2005) Diagnosis and Management of the Poisoned Child. Pediatric Annals 34:12, pages 937-946.
Crossref
Christopher P. Holstege & Stephen Dobmeier. (2005) Cardiovascular Challenges in Toxicology. Emergency Medicine Clinics of North America 23:4, pages 1195-1217.
Crossref
D M WoodK D Wright, A L Jones & P I Dargan. (2016) Metaraminol (Aramine®) in the management of a significant amlodipine overdose. Human & Experimental Toxicology 24:7, pages 377-381.
Crossref
Matthew Hedge. (2016) Calcium Channel Blocker Toxicology. Journal of Pharmacy Practice 18:3, pages 169-174.
Crossref
Angela C. Anderson. (2005) Calcium-Channel Blocker Overdose. Clinical Pediatric Emergency Medicine 6:2, pages 109-115.
Crossref
Greene Shepherd & Wendy Klein-Schwartz. (2005) High-Dose Insulin Therapy for Calcium-Channel Blocker Overdose. Annals of Pharmacotherapy 39:5, pages 923-930.
Crossref
G. MaclarenW. ButtP. CameronA. Preovolos, R. Mcegan & S. Marasco. (2019) Treatment of Polypharmacy Overdose with Multimodality Extracorporeal Life Support. Anaesthesia and Intensive Care 33:1, pages 120-123.
Crossref
Matthew D. Sztajnkrycer, G. Randall Bond, Susan B. Johnson & Amy L. Weaver. (2004) Use of Vasopressin in a Canine Model of Severe Verapamil Poisoning: A Preliminary Descriptive Study. Academic Emergency Medicine 11:12, pages 1253-1261.
Crossref
Joshua B. Michael & Matthew D. Sztajnkrycer. (2004) Deadly pediatric poisons: nine common agents that kill at low doses. Emergency Medicine Clinics of North America 22:4, pages 1019-1050.
Crossref
Masaya Arikawa, Naohiko Takahashi, Tetsuya Kira, Masahide Hara, Hironobu Yoshimatsu & Tetsunori Saikawa. (2004) Attenuated Inhibition of L-type Calcium Currents by Troglitazone in Fructose–Fed Rat Cardiac Ventricular Myocytes. Journal of Cardiovascular Pharmacology 44:1, pages 109-116.
Crossref
L. Min & K. Deshpande. (2004) Diltiazem Overdose Haemodynamic Response to Hyperinsulinaemia-Euglycaemia Therapy: A Case Report. Critical Care and Resuscitation 6:1, pages 28-30.
Crossref
Christopher R DeWitt & Javier C Waksman. (2004) Pharmacology, Pathophysiology and Management of Calcium Channel Blocker and ??-Blocker Toxicity. Toxicological Reviews 23:4, pages 223-238.
Crossref
Bruno M??garbane, Souheil Karyo & Fr??d??ric J Baud. (2004) The Role of Insulin and Glucose (Hyperinsulinaemia/Euglycaemia) Therapy in Acute Calcium Channel Antagonist and ??-Blocker Poisoning. Toxicological Reviews 23:4, pages 215-222.
Crossref
Janice L. Zimmerman. (2003) Poisonings and overdoses in the intensive care unit: General and specific management issues. Critical Care Medicine 31:12, pages 2794-2801.
Crossref
&NA;. (2003) Calcium channel antagonist overdose is best managed with decontamination, antidotes and supportive care. Drugs & Therapy Perspectives 19:10, pages 20-23.
Crossref
Ian Whyte, Nick Buckley & Andrew Dawson. (2003) Calcium Channel Blockers. Medicine 31:10, pages 37-40.
Crossref
L. Rasmussen, S. E. Husted & S. P. Johnsen. (2003) Severe intoxication after an intentional overdose of amlodipine. Acta Anaesthesiologica Scandinavica 47:8, pages 1038-1040.
Crossref
Maria Marques, Ernestina Gomes & Júlio de Oliveira. (2003) Treatment of calcium channel blocker intoxication with insulin infusion: case report and literature review. Resuscitation 57:2, pages 211-213.
Crossref
Babak Mokhlesi, Jerrold B. Leikin, Patrick Murray & Thomas C. Corbridge. (2003) Adult Toxicology in Critical Carea. Chest 123:3, pages 897-922.
Crossref
Gopikrishna Punukollu, Ramesh M. Gowda, Ijaz A. Khan & Ozgen M. Dogan. (2003) Delayed Presentation of Calcium Channel Antagonist Overdose. American Journal of Therapeutics 10:2, pages 132-134.
Crossref
Slavica Vucinic, Zarko Vucinic, Zoran Segrt, Dragan Joksovic, Dusan Jovanovic & Veljko Todorovic. (2003) Acute poisoning by cardiovascular agents. Vojnosanitetski pregled 60:6, pages 691-696.
Crossref
Steven D. Salhanick & Michael W. Shannon. (2003) Management of Calcium Channel Antagonist Overdose. Drug Safety 26:2, pages 65-79.
Crossref
L.I.G. Worthley. (2002) Clinical Toxicology: Part I. Diagnosis and Management of Common Drug Overdosage. Critical Care and Resuscitation 4:3, pages 192-215.
Crossref
Jason Chu, Richard Y. Wang & Nicholas S. Hill. (2002) Update in Clinical Toxicology. American Journal of Respiratory and Critical Care Medicine 166:1, pages 9-15.
Crossref
EDWARD W. BOYER, PETER A. DUIC & ADELAIDE EVANS. (2002) Hyperinsulinemia/euglycemia therapy for calcium channel blocker poisoning. Pediatric Emergency Care 18:1, pages 36-37.
Crossref
Gina Abbruzzi & Christine M Stork. (2002) Pediatric toxicologic concerns. Emergency Medicine Clinics of North America 20:1, pages 223-247.
Crossref
. 2001. Dreisbach's Handbook of Poisoning. Dreisbach's Handbook of Poisoning 459 484 .
Robert E. Hill, Kennon Heard, Gregory M. Bogdan, Charles B. Cairns & Richard C. Dart. (2008) Attenuation of Verapamil‐induced Myocardial Toxicity in an Ex‐vivo Rat Model Using a Verapamil‐specific Ovine Immunoglobin. Academic Emergency Medicine 8:10, pages 950-955.
Crossref
Edward W. Boyer & Michael Shannon. (2001) Treatment of Calcium-Channel–Blocker Intoxication with Insulin Infusion. New England Journal of Medicine 344:22, pages 1721-1722.
Crossref
. (2000) Part 10: Pediatric Advanced Life Support. Circulation 102:suppl_1.
Crossref
. (2000) Part 10: Pediatric Advanced Life Support. Resuscitation 46:1-3, pages 343-399.
Crossref
Erica L. Liebelt. (2000) Newer antidotal therapies for pediatric poisonings. Clinical Pediatric Emergency Medicine 1:3, pages 234-243.
Crossref

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