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Research Article

Effect of Ethanol and pH on the Adsorption of Acetaminophen (Paracetamol) to High Surface Activated Charcoal, In Vitro Studies

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Pages 59-67 | Published online: 29 Apr 2002

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Lotte C. G. Hoegberg, Greene Shepherd, David M. Wood, Jami Johnson, Robert S. Hoffman, E. Martin Caravati, Wui Ling Chan, Silas W. Smith, Kent R. Olson & Sophie Gosselin. (2021) Systematic review on the use of activated charcoal for gastrointestinal decontamination following acute oral overdose. Clinical Toxicology 59:12, pages 1196-1227.
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Lotte Christine Groth Hoegberg, Thor Buch Groenlykke, Ulla Abildtrup & Helle Riis Angelo. (2010) Combined paracetamol and amitriptyline adsorption to activated charcoal. Clinical Toxicology 48:9, pages 898-903.
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Lotte Christine Groth Hoegberg, Anne-Bolette Christophersen, Hanne Rolighed Christensen & Helle Riis Angelo. (2005) Comparison of the Adsorption Capacities of an Activated-Charcoal–Yogurt Mixture Versus Activated-Charcoal–Water Slurry In Vivo and In Vitro. Clinical Toxicology 43:4, pages 269-275.
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American Academy of Clinical Toxicology & European Association of Poisons Centres and Clinical Toxicologists. (2005) Position Paper: Single-Dose Activated Charcoal. Clinical Toxicology 43:2, pages 61-87.
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Articles from other publishers (13)

Mircea Stefan, Ioana Stefan, Ioana-Alexandra Negoita, Viorel Ordeanu & Daniela Simina Stefan. (2021) Influence of Internal Structure of the Sorbents on Diazepam Sorption from Simulated Intestinal Fluid. Applied Sciences 11:3, pages 1158.
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Shobha Regmi, Balmukunda Regmi, Sajan Lal Shyaula, Shiva Pathak, Bishnu Prasad Bhattarai & Saroj Kumar Sah. (2017) In Vitro Study of Adsorption Kinetics of Dextromethorphan Syrup onto Activated Charcoal in Simulated Gastric and Intestinal Fluids. Journal of Chemistry 2017, pages 1-7.
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Carlos A Rey-Mafull, Juan E Tacoronte, Raquel Garcia, Jorge Tobella, Julio C Llópiz, Alberto Iglesias & Dachamir Hotza. (2014) Comparative study of the adsorption of acetaminophen on activated carbons in simulated gastric fluid. SpringerPlus 3:1.
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Seung-Woo Nam, Dae-Jin Choi, Seung-Kyu Kim, Namguk Her & Kyung-Duk Zoh. (2014) Adsorption characteristics of selected hydrophilic and hydrophobic micropollutants in water using activated carbon. Journal of Hazardous Materials 270, pages 144-152.
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Masakazu Miyachi & Hiraku Onishi. (2013) In Vitro Evaluation of Medicinal Carbon Granules by Wet Granulation Method Using Carboxymethylcellulose Sodium as a Binding Agent. Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) 39:10, pages 599-607.
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Anne-Bolette Jill Gude, Lotte Christine Groth Hoegberg, Helle Riis Angelo & Hanne Rolighed Christensen. (2009) Dose-Dependent Adsorptive Capacity of Activated Charcoal for Gastrointestinal Decontamination of a Simulated Paracetamol Overdose in Human Volunteers. Basic & Clinical Pharmacology & Toxicology 106:5, pages 406-410.
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Taiga Sakazaki, Kazuhiro Yoshimura & Motoi Machida. (2010) Preparation of KOH and Steam Two-step Activated Carbons from Coconut Shell Char and Their Adsorption Properties. Mokuzai Gakkaishi 56:4, pages 251-257.
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Sabina Beninati, Domenica Semeraro & Marina Mastragostino. (2008) Adsorption of Paracetamol and Acetylsalicylic Acid onto Commercial Activated Carbons. Adsorption Science & Technology 26:9, pages 721-734.
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W. Stephen Waring, Alexandra F. Stephen, Aleksandra M. Malkowska & Oliver D.G. Robinson. (2008) Acute Ethanol Coingestion Confers a Lower Risk of Hepatotoxicity after Deliberate Acetaminophen Overdose. Academic Emergency Medicine 15:1, pages 54-58.
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Darren M Roberts & Nick A Buckley. (2007) Pharmacokinetic Considerations in Clinical Toxicology. Clinical Pharmacokinetics 46:11, pages 897-939.
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Lotte Christine Groth Hoegberg, Helle Riis Angelo, Anne Bolette Christophersen & Hanne Rolighed Christensen. (2003) The Effect of Food and Ice Cream on the Adsorption Capacity of Paracetamol to High Surface Activated Charcoal: In vitro Studies. Pharmacology and Toxicology 93:5, pages 233-237.
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David N. Bailey & John R. Briggs. (2003) The Effect of Ethanol and pH on the Adsorption of Drugs From Simulated Gastric Fluid Onto Activated Charcoal. Therapeutic Drug Monitoring 25:3, pages 310-313.
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David Novak & James H. Lewis. (2003) Drug-induced liver disease. Current Opinion in Gastroenterology 19:3, pages 203-215.
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