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Research Article

Clonidine Toxicity Revisited

Pages 145-155 | Published online: 17 Jun 2002

Keep up to date with the latest research on this topic with citation updates for this article.

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Geoffrey K. Isbister, Simon P. Heppell, Colin B. Page & Nicole M. Ryan. (2017) Adult clonidine overdose: prolonged bradycardia and central nervous system depression, but not severe toxicity. Clinical Toxicology 55:3, pages 187-192.
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J. A. Lowry & J. T. Brown. (2014) Significance of the imidazoline receptors in toxicology. Clinical Toxicology 52:5, pages 454-469.
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Articles from other publishers (38)

井上 史也岡崎 悠治市場 稔久柏 健一郎. (2023) 遅発性に低血圧とQT延長が生じたグアンファシン中毒の1例(Delayed hypotension and prolonged QT interval due to guanfacine poisoning). Nihon Kyukyu Igakukai Zasshi: Journal of Japanese Association for Acute Medicine 34:10, pages 423-428.
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Jagdeep Bhullar, Arti Patel, Jaagruthi Chitithoti, Frederick Venter, Theingi Win & Fowrooz Joolhar. (2022) Clonidine Overdose as an Unusual Cause of Heart Failure. Journal of Investigative Medicine High Impact Case Reports 10, pages 232470962211068.
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Michael S. Toce, Eli Freiman, Katherine A. O’Donnell & Michele M. Burns. (2021) Clinical Effects of Pediatric Clonidine Exposure: A Retrospective Cohort Study at a Single Tertiary Care Center. The Journal of Emergency Medicine 60:1, pages 58-66.
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C. James Watson, James D. Whitledge, Alexander F. Barbuto, Katherine L. Boyle & Michael Ganetsky. (2020) Toxicity of agents used for opioid withdrawal: a case-based approach. International Anesthesiology Clinics 58:2, pages 19-27.
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Nicole Nadeau, Margaret Samuels-Kalow, Kathleen Wittels & Susan R. Wilcox. (2019) A Common Antidote for an Uncommon Indication. The Journal of Emergency Medicine 57:5, pages 723-725.
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Michael S. Toce & Todd W. Lyons. (2019) Case 1: A Medically Complex 10-month-old Boy with Lethargy. Pediatrics In Review 40:2, pages 79-81.
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Jian-Da Lu & Jun Xue. 2019. Critical Care Nephrology. Critical Care Nephrology 600 629.e7 .
Michael S. Toce, Peter R. Chai, Michele M. Burns & Edward W. Boyer. (2018) Pharmacologic Treatment of Opioid Use Disorder: a Review of Pharmacotherapy, Adjuncts, and Toxicity. Journal of Medical Toxicology 14:4, pages 306-322.
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Sang Ju Lee, Hyeree Kim & Hei Sung Kim. (2018) Topical Brimonidine Tartrate 0.33% Gel on Postlaser Erythema: Our Experience and Review of the Literature. Dermatologic Surgery 44:1, pages 144-147.
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Spencer Greene, Erin AufderHeide & Lindsay French-Rosas. (2017) Toxicologic Emergencies in Patients with Mental Illness. Psychiatric Clinics of North America 40:3, pages 519-532.
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Scott Lucyk & Lewis S. Nelson. 2017. Critical Care Toxicology. Critical Care Toxicology 2907 2911 .
Anthony J. Tomassoni. 2017. Critical Care Toxicology. Critical Care Toxicology 751 769 .
Allison Lowe GuimeraDeepa Kulkarni. (2016) Case 3: Altered Mental Status in a 14-Year-Old Girl. Pediatrics In Review 37:4, pages 175-176.
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Anthony J. Tomassoni. 2016. Critical Care Toxicology. Critical Care Toxicology 1 19 .
Syed A. Ahmad, Dennis Scolnik, Vala Snehal & Miguel Glatstein. (2015) Use of Naloxone for Clonidine Intoxication in the Pediatric Age Group. American Journal of Therapeutics 22:1, pages e14-e16.
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Scott Lucyk & Lewis S. Nelson. 2016. Critical Care Toxicology. Critical Care Toxicology 1 5 .
Suad A. Al-Abri, He S. Yang & Kent R. Olson. (2014) Unintentional Pediatric Ophthalmic Tetrahydrozoline Ingestion: Case Files of the Medical Toxicology Fellowship at the University of California, San Francisco. Journal of Medical Toxicology 10:4, pages 388-391.
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Andrew N. Pfeffer & Saralyn R. Williams. (2014) Treatment of Calcium Channel Blocker Poisoning: Should We Reprioritize Our Potpourri of Treatment Options?. Annals of Emergency Medicine 63:2, pages 259-265.
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George Sam Wang, Marie-Claire Le Lait & Kennon Heard. (2014) Unintentional Pediatric Exposures to Central Alpha-2 Agonists Reported to the National Poison Data System. The Journal of Pediatrics 164:1, pages 149-152.
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Daniel S. Tsze & Peter S. Dayan. (2012) Treatment of Guanfacine Toxicity With Naloxone. Pediatric Emergency Care 28:10, pages 1060-1061.
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Jeanna M. MarraffaVictor CohenMary Ann Howland. (2012) Antidotes for toxicological emergencies: A practical review. American Journal of Health-System Pharmacy 69:3, pages 199-212.
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Pavan M. Patil & Seema P. Patil. (2012) Is Clonidine an Adequate Alternative to Epinephrine as a Vasoconstrictor in Patients With Hypertension?. Journal of Oral and Maxillofacial Surgery 70:2, pages 257-262.
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Melissa L. Givens. (2012) Toxic Bradycardias in the Critically Ill Poisoned Patient. Emergency Medicine International 2012, pages 1-6.
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Hong-Guang Xie, Ying Jun Cao, Estelle B. Gauda, Alexander G. Agthe, Craig W. Hendrix & Howard Lee. (2011) Clonidine Clearance Matures Rapidly During the Early Postnatal Period: A Population Pharmacokinetic Analysis in Newborns With Neonatal Abstinence Syndrome. The Journal of Clinical Pharmacology 51:4, pages 502-511.
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Lindsay Murray, Frank Daly, Mark Little & Mike Cadogan. 2011. Toxicology Handbook. Toxicology Handbook 127 370 .
Selahattin Katar, Mustafa Taskesen & Nilüfer Okur. (2009) Naloxone use in a newborn with apnea due to tetrahydrozoline intoxication. Pediatrics International 52:3, pages 488-489.
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Frank Barile. 2010. Clinical Toxicology. Clinical Toxicology 150 163 .
Gregory A. Hollman, David B. Allen, Jens C. Eickhoff & Aaron L. Carrel. (2010) Respiratory Depression in Young Prader Willi Syndrome Patients following Clonidine Provocation for Growth Hormone Secretion Testing. International Journal of Pediatric Endocrinology 2010, pages 1-8.
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Silas W. Smith. 2010. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology 397 460 .
Polwattage M S Perera, Shaluka F Jayamanna, Raja Hettiarachchi, Chandana Abeysinghe, Harindra Karunatilake, Andrew H Dawson & Nick A Buckley. (2009) A phase II clinical trial to assess the safety of clonidine in acute organophosphorus pesticide poisoning. Trials 10:1.
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Theodoros Kelesidis & Iosif Kelesidis. (2009) Unexplained high fever in an elderly patient treated with clonidine, duloxetine, and atorvastatin. Clinical Therapeutics 31:12, pages 2894-2899.
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Dingwei Kuang, Claudio Ronco & Nicholas A. Hoenich. 2009. Critical Care Nephrology. Critical Care Nephrology 931 954 .
Melissa L Givens & Ellen O’Connell. (2007) Toxicologic issues during cardiopulmonary resuscitation. Current Opinion in Critical Care 13:3, pages 287-293.
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MATTHEW D. SZTAJNKRYCER. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 695 702 .
Blaine E. Benson, Daniel A. Spyker, William G. Troutman & William A. Watson. (2006) TESS-based dose–response using pediatric clonidine exposures. Toxicology and Applied Pharmacology 213:2, pages 145-151.
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Joshua B. Michael & Matthew D. Sztajnkrycer. (2004) Deadly pediatric poisons: nine common agents that kill at low doses. Emergency Medicine Clinics of North America 22:4, pages 1019-1050.
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. (2004) No Sympathy for a Boy With Obtundation. Pediatric Emergency Care 20:6, pages 403-406.
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Hans Juha Exner, Jürgen Peters & Matthias Eikermann. (2003) Epidural Analgesia at End of Life: Facing Empirical Contraindications. Anesthesia & Analgesia 97:6, pages 1740-1742.
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