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Research Article

The Clinical Picture of Olanzapine Poisoning with Special Reference to Fluctuating Mental Status

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Pages 27-32 | Received 03 Jan 2003, Accepted 22 Jul 2003, Published online: 15 Mar 2004

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S. Handley, M. X. Patel & R. J. Flanagan. (2016) Antipsychotic-related fatal poisoning, England and Wales, 1993–2013: impact of the withdrawal of thioridazine. Clinical Toxicology 54:6, pages 471-480.
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. (2008) Correspondence. Australian and New Zealand Journal of Psychiatry 42:5, pages 430-436.
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Daniel J. Cobaugh, Andrew R. Erdman, Lisa L. Booze, Elizabeth J. Scharman, Gwenn Christianson, Anthony S. Manoguerra, E. Martin Caravati, Peter A. Chyka, Alan D. Woolf, Lewis S. Nelson & William G. Troutman. (2007) Atypical antipsychotic medication poisoning: An evidence-based consensus guideline for out-of-hospital management. Clinical Toxicology 45:8, pages 918-942.
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Salomé Ballesteros, María A. Martínez, M. Angeles Ballesteros, Carolina Sánchez de la Torre & Juan C. Rodríguez-Borregán. (2007) A severe case of olanzapine overdose with analytical data. Clinical Toxicology 45:4, pages 412-415.
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Articles from other publishers (29)

Masatoshi Inoue. (2023) Respiratory Depression Caused by Low Dose of Olanzapine: A Case Report.. Psiquiatría Biológica, pages 100412.
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Kevin R. SchwartzAbigail L. DonovanBryan D. HayesMai UchidaJoy B. Rosen. (2023) Case 16-2023: A 13-Year-Old Boy with Depression and Hypotension. New England Journal of Medicine 388:21, pages 1992-1999.
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Asmaa F Sharif, Zeinab A Kasemy, Rakan A Alshabibi, Salem J Almufleh, Fahad W Abousamak, Abdulmajeed A Alfrayan, Muath Alshehri, Rakan A Alemies, Assim S Almuhsen, Shahd N AlNasser & Khalid A Al-Mulhim. (2023) Prognostic factors in acute poisoning with central nervous system xenobiotics: development of a nomogram predicting risk of intensive care unit admission. Toxicology Research 12:1, pages 62-75.
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Tyler J. Torrico. (2022) The pathophysiology of rapid fluctuations in mental status associated with olanzapine: A case report. Frontiers in Psychiatry 13.
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Snežana Đorđević, Nataša Perković Vukčević, Marko Antunović, Vesna Kilibarda, Gordana Vuković Ercegović, Jasmina Jović Stošić & Slavica Vučinić. (2022) Olanzapine poisoning in patients treated at the National Poison Control Centre in Belgrade, Serbia in 2017 and 2018: a brief review of serum concentrations and clinical symptoms. Archives of Industrial Hygiene and Toxicology 73:2, pages 126-130.
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Andrew R Kolarich, Matthew Mubarak, Shannon Wells, Christopher T Campbell & Ravi S Samraj. (2018) A case of sinus pause induced by swallowing in the setting of olanzapine and guanfacine overdose. Journal of the Intensive Care Society 20:3, pages 277-280.
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Jeffrey Guina, Sayon Roy, Ankur Gupta, Daniel D. Langleben & Igor Elman. (2017) Oral glucose tolerance test performance in olanzapine-treated schizophrenia-spectrum patients is predicted by BMI and triglycerides but not olanzapine dose or duration. Human Psychopharmacology: Clinical and Experimental 32:4, pages e2604.
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Evan S. Schwarz, Kathryn T. Kopec, Timothy J. Wiegand, Paul M. Wax & Jeffrey Brent. (2017) Should We Be Using the Poisoning Severity Score?. Journal of Medical Toxicology 13:2, pages 135-145.
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YingYing Duan & Zheng Wang. (2016) To Explore the Characteristics of Fatality in Children Poisoned by Paraquat – with Analysis of 146 Cases. The International Journal of Artificial Organs 39:2, pages 51-55.
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Robert J. Flanagan & Peter Manu. 2016. Life-Threatening Effects of Antipsychotic Drugs. Life-Threatening Effects of Antipsychotic Drugs 333 349 .
Yanko T. Iliev, Marin Y. Zagorov & Janet G. Grudeva-Popova. (2015) Acute Poisoning with Dapsone and Olanzapine: Severe Methemoglobinemia and Coma with a Favourable Outcome / Острое Отравление Медикаментами Dapsone И Olanzapine: Тяжёлая Метгемоглобинемия И Кома С Благоприятным Исходом. Folia Medica 57:2, pages 122-126.
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Joanne Y.T. Leung, Catherine C.Y. Pang, Ric M. Procyshyn & Alasdair M. Barr. (2014) Cardiovascular effects of acute treatment with the antipsychotic drug olanzapine in rats. Vascular Pharmacology 62:3, pages 143-149.
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Daniel B Kurbanov, Paul J Currie, Donald C Simonson, David Borsook & Igor Elman. (2012) Effects of naltrexone on food intake and body weight gain in olanzapine-treated rats. Journal of Psychopharmacology 26:9, pages 1244-1251.
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Michael Levine & Anne-Michelle Ruha. (2012) Overdose of Atypical Antipsychotics. CNS Drugs 26:7, pages 601-611.
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Hadia FarooqRebecca ReithAnna Roskilly & Andrew Solomon. (2011) Acutely admitted patients who have taken an overdose: a practical update. British Journal of Hospital Medicine 72:Sup7, pages M104-M108.
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Nienke A.G. LankheetRoos D. PadbergEvelyne M. de KluiverAbraham J. WilhelmJob B.M. van WoenselJos H. BeijnenAlwin D.R. Huitema. (2011) Relatively Mild Symptoms After an Olanzapine Intoxication in a 2-Year-Old Girl with Excessively High Serum Levels. Journal of Child and Adolescent Psychopharmacology 21:1, pages 93-95.
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Lindsay Murray, Frank Daly, Mark Little & Mike Cadogan. 2011. Toxicology Handbook. Toxicology Handbook 127 370 .
Hock Heng Tan, Jason Hoppe & Kennon Heard. (2009) A systematic review of cardiovascular effects after atypical antipsychotic medication overdose. The American Journal of Emergency Medicine 27:5, pages 607-616.
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Melissa Guarieiro Ramos, Munir Murad, Cláudia Hara & Fábio Lopes Rocha. (2008) Nonfatal Suicidal Olanzapine Intoxication. Journal of Clinical Psychopharmacology 28:5, pages 578.
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George H. Tse, Maria H. Warner & W. Stephen Waring. (2008) Prolonged toxicity after massive olanzapine overdose: two cases with confirmatory laboratory data. The Journal of Toxicological Sciences 33:3, pages 363-365.
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Mary Morgan, L. Peter Hackett & Geoffrey K. Isbister. (2007) Olanzapine overdose: a series of analytically confirmed cases. International Clinical Psychopharmacology 22:3, pages 183-186.
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W S Waring, J Wrate & D N Bateman. (2016) Olanzapine overdose is associated with acute muscle toxicity. Human & Experimental Toxicology 25:12, pages 735-740.
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A. A. CEVIK, I. UNLUOGLU, S. YANTURALI, S. KALKAN & A. SAHIN. (2006) Interrelation between the Poisoning Severity Score, carboxyhaemoglobin levels and in-hospital clinical course of carbon monoxide poisoning. International Journal of Clinical Practice 60:12, pages 1558-1564.
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Igor Elman, David Borsook & Scott E Lukas. (2006) Food Intake and Reward Mechanisms in Patients with Schizophrenia: Implications for Metabolic Disturbances and Treatment with Second-Generation Antipsychotic Agents. Neuropsychopharmacology 31:10, pages 2091-2120.
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Manu Arora & Samir Kumar Praharaj. (2006) Nonfatal Suicidal Olanzapine Overdose. Clinical Neuropharmacology 29:4, pages 190-191.
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Ragy R. Girgis, Harpreet S. Duggal & Antoine B. Douaihy. (2006) Respiratory depression from Symbyax ® overdose and binge drinking. General Hospital Psychiatry 28:3, pages 255-256.
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Frank M. TheisenJustyna GrabarkiewiczChristine FegbeutelAnja HübnerClaudia Mehler-WexHelmut Remschmidt. (2005) Olanzapine Overdose in Children and Adolescents: Two Case Reports and a Review of the Literature. Journal of Child and Adolescent Psychopharmacology 15:6, pages 986-995.
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C. Griffiths & R. J. Flanagan. (2016) Fatal poisoning with antipsychotic drugs, England and Wales 1993-2002. Journal of Psychopharmacology 19:6, pages 667-674.
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Dale DuBois. (2005) Toxicology and overdose of atypical antipsychotic medications in children: does newer necessarily mean safer?. Current Opinion in Pediatrics 17:2, pages 227-233.
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