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Journal of Toxicology: Clinical Toxicology Volume 42, 2004 - Issue 4
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Research Article

The Effect of Calcium Chloride in Treating Hyperkalemia Due to Acute Digoxin Toxicity in a Porcine Model

Jason B. Hack Division of Toxicology, The Brody School of Medicine, East Carolina University, CarolinaUSA; Department of Emergency Medicine, The Brody School of Medicine, East Carolina University, CarolinaUSA; , 600 Moye Blvd, Greenville, North Carolina, 27858, USA
, M.D.,
Jonathan H. Woody Department of Emergency Medicine, The Brody School of Medicine, East Carolina University, CarolinaUSA
, M.D.,
Daniel E. Lewis Department of Emergency Medicine, The Brody School of Medicine, East Carolina University, CarolinaUSA
, M.D.,
Kori Brewer Department of Emergency Medicine, The Brody School of Medicine, East Carolina University, CarolinaUSA
, Ph.D. &
William J. Meggs Division of Toxicology, The Brody School of Medicine, East Carolina University, CarolinaUSA; Department of Emergency Medicine, The Brody School of Medicine, East Carolina University, CarolinaUSA
, M.D., Ph.D.
Pages 337-342 | Received 28 Oct 2003, Accepted 26 Feb 2004, Published online: 16 Aug 2004

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Jeffrey M Turner. (2013) Treatment of hyperkalemia. Expert Opinion on Orphan Drugs 1:5, pages 359-371.
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Senaka Rajapakse. (2009) Management of yellow oleander poisoning. Clinical Toxicology 47:3, pages 206-212.
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Yi-Cheng Tsai, Chun-Yu Chen, Ning-I Yang & Chen-Chang Yang. (2008) Cardiac glycoside poisoning following suicidal ingestion of Cerbera manghas. Clinical Toxicology 46:4, pages 340-341.
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Eric J. Lavonas, Peter D. Akpunonu, Ann M. Arens, Kavita M. Babu, Dazhe Cao, Robert S. Hoffman, Christopher O. Hoyte, Maryann E. Mazer-Amirshahi, Andrew Stolbach, Maude St-Onge, Trevonne M. Thompson, George Sam Wang, Amber V. Hoover & Ian R. Drennan. (2023) 2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation.
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Ruixue Tian, Rongshan Li & Xiaoshuang Zhou. (2023) Recent Progresses in Non-Dialysis Chronic Kidney Disease Patients with Hyperkalemia: Outcomes and Therapeutic Strategies. Medicina 59:2, pages 353.
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Jon B. Cole & Ann M. Arens. (2022) Cardiotoxic Medication Poisoning. Emergency Medicine Clinics of North America 40:2, pages 395-416.
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Mohamed Serhan Hamam & Andrew Bissonette. (2021) Evaluation and Management of Toxicological Causes of Delirium. Current Emergency and Hospital Medicine Reports 9:3, pages 55-63.
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M. I. Sperling, E. G. Kruchinin & A. S. Gogolevsky. (2021) Pharmacological aspects of acute treatment glycoside intoxication. Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) 11:4, pages 120-134.
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Sage P. Whitmore & Kyle J. Gunnerson. 2020. Emergency Department Critical Care. Emergency Department Critical Care 301 329 .
Ehab Said Aki, Waleed Awad Salem & Jalal Alessai. 2019. Essentials of Accident and Emergency Medicine. Essentials of Accident and Emergency Medicine.
Ivan Barisic, Diana Balenovic, Robert Klicek, Bozo Radic, Bojana Nikitovic, Domagoj Drmic, Mario Udovicic, Dean Strinic, Darija Bardak, Lidija Berkopic, Viktor Djuzel, Marko Sever, Ivan Cvjetko, Zeljko Romic, Aleksandra Sindic, Martina Lovric Bencic, Sven Seiwerth & Predrag Sikiric. (2013) Mortal hyperkalemia disturbances in rats are NO-system related. The life saving effect of pentadecapeptide BPC 157. Regulatory Peptides 181, pages 50-66.
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Kirk L. Cumpston. 2013. Emergency Medicine. Emergency Medicine 1266 1279.e1 .
Salmaan Kanji & Robert D. MacLean. (2012) Cardiac Glycoside Toxicity. Critical Care Clinics 28:4, pages 527-535.
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Melissa L. Givens. (2012) Toxic Bradycardias in the Critically Ill Poisoned Patient. Emergency Medicine International 2012, pages 1-6.
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Lauren M. Dandeles & Kirsten H. Ohler. (2012) Pharmacotherapy of Pediatric Advanced Life Support and Toxicological Emergencies. AACN Advanced Critical Care 23:4, pages 398-412.
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Michael Levine, Heikki Nikkanen & Daniel J. Pallin. (2011) The Effects of Intravenous Calcium in Patients with Digoxin Toxicity. The Journal of Emergency Medicine 40:1, pages 41-46.
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David J. Roberts. 2010. Rosen's Emergency Medicine – Concepts and Clinical Practice. Rosen's Emergency Medicine – Concepts and Clinical Practice 1978 1988 .
Tami O. Tiamfook-Morgan, David F.M. Brown & Eric S. Nadel. (2008) Bradycardia and Confusion. The Journal of Emergency Medicine 34:4, pages 451-455.
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Christian P. Erickson & Kent R. Olson. (2008) Case files of the medical toxicology fellowship of the California poison control system—San Francisco: Calcium plus digoxin—More taboo than toxic?. Journal of Medical Toxicology 4:1, pages 33-39.
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FRÉDÉRIC LAPOSTOLLE & STEPHEN W. BORRON. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 949 962 .
. (2006) Case 24-2006: A Woman with Hypotension after an Overdose of Amlodipine. New England Journal of Medicine 355:18, pages 1936-1938.
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D M WoodK D Wright, A L Jones & P I Dargan. (2016) Metaraminol (Aramine®) in the management of a significant amlodipine overdose. Human & Experimental Toxicology 24:7, pages 377-381.
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