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Research Article

The Effects of Fresh Frozen Plasma on Cholinesterase Levels and Outcomes in Patients with Organophosphate Poisoning

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Pages 617-623 | Received 18 Feb 2004, Accepted 12 May 2004, Published online: 30 Aug 2004

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Farzad Gheshlaghi, Mahsa Akafzadeh Savari, Rozita Nasiri, Anselm Wong, Awat Feizi, Mohammad Reza Maracy, Gholamali Dorooshi, Rokhsareh Meamar & Nastaran Eizadi-Mood. (2020) Efficacy of fresh frozen plasma transfusion in comparison with conventional regimen in organophosphate poisoning treatment: a meta-analysis study. Critical Reviews in Toxicology 50:8, pages 677-684.
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Kishore Pichamuthu, Jayakumar Jerobin, Anupama Nair, George John, Joseph Kamalesh, Kurien Thomas, Arun Jose, Jude Joseph Fleming, Anand Zachariah, Suresh S. David, Dolly Daniel & John Victor Peter. (2010) Bioscavenger therapy for organophosphate poisoning – an open-labeled pilot randomized trial comparing fresh frozen plasma or albumin with saline in acute organophosphate poisoning in humans. Clinical Toxicology 48:8, pages 813-819.
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John Victor Peter, John L Moran & Petra L Graham. (2007) Advances in the management of organophosphate poisoning. Expert Opinion on Pharmacotherapy 8:10, pages 1451-1464.
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. (2005) FFP in Organophosphate Poisoning: What's the Secret Ingredient?. Clinical Toxicology 43:3, pages 215-215.
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Giuliano Pasquale Ramadori. (2023) Organophosphorus Poisoning: Acute Respiratory Distress Syndrome (ARDS) and Cardiac Failure as Cause of Death in Hospitalized Patients. International Journal of Molecular Sciences 24:7, pages 6658.
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Nimesh Lageju, Durga Neupane, Lokesh Shekher Jaiswal, Suresh Chapagain, Pratik Uprety, Swapnil Regmi & Silan Bhandari. (2022) Intermediate syndrome following organophosphate poisoning: A case report in a low resource and poor socio‐economic setting. Clinical Case Reports 10:10.
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Libin Zhang, Hironobu Murata, Gabriel Amitai, Paige N. Smith, Krzysztof Matyjaszewski & Alan J. Russell. (2020) Catalytic Detoxification of Organophosphorus Nerve Agents by Butyrylcholinesterase-Polymer-Oxime Bioscavengers. Biomacromolecules 21:9, pages 3867-3877.
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Patrick Masson & Sofya V. Lushchekina. 2020. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 1199 1229 .
Libin Zhang, Stefanie L. Baker, Hironobu Murata, Nicholas Harris, Weihang Ji, Gabriel Amitai, Krzysztof Matyjaszewski & Alan J. Russell. (2019) Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer‐Based Protein Engineering. Advanced Science 7:1, pages 1901904.
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Stephanie M. Bester, Mark A. Guelta, Jonah Cheung, Mark D. Winemiller, Su Y. Bae, James Myslinski, Scott D. Pegan & Jude J. Height. (2018) Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6. Chemical Research in Toxicology 31:12, pages 1405-1417.
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Raluca Ecaterina Haliga, Bianca Codrina Morarasu, Manuela Ursaru, Viorica Irimioaia & Laurentiu Sorodoc. (2018) New insights into the organophosphate-induced intermediate syndrome. Archives of Industrial Hygiene and Toxicology 69:2, pages 191-195.
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Yvonne J. Rosenberg & James B. Fink. (2016) Creation of a protective pulmonary bioshield against inhaled organophosphates using an aerosolized bioscavenger. Annals of the New York Academy of Sciences 1374:1, pages 151-158.
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Nezihat Rana Disel, Ayca Acikalin, Zeynep Kekec & Ahmet Sebe. (2016) Utilization of plasmapheresis for organophosphate intoxication: A case report. Turkish Journal of Emergency Medicine 16:2, pages 69-71.
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Jens von der Wellen, Anne Bierwisch, Franz Worek, Horst Thiermann & Timo Wille. (2016) Kinetics of pesticide degradation by human fresh frozen plasma (FFP) in vitro. Toxicology Letters 244, pages 124-128.
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Brian C. Geyer. 2016. Ciottone's Disaster Medicine. Ciottone's Disaster Medicine 651 655 .
Yvonne J. Rosenberg, Jeremy Walker, Xiaoming Jiang, Scott Donahue, Jason Robosky, Markus Sack, Jonathan Lees & Lori Urban. (2015) A highly stable minimally processed plant-derived recombinant acetylcholinesterase for nerve agent detection in adverse conditions. Scientific Reports 5:1.
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Yvonne J. Rosenberg, Jeffery Gearhart, Lingjun Mao, Xiaoming Jiang & Segundo Hernandez-Abanto. (2014) Protection against paraoxon toxicity by an intravenous pretreatment with polyethylene-glycol-conjugated recombinant butyrylcholinesterase in macaques. Chemico-Biological Interactions 210, pages 20-25.
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Rakesh K. Sit, Valery V. Fokin, Gabriel Amitai, K. Barry Sharpless, Palmer Taylor & Zoran Radić. (2014) Imidazole Aldoximes Effective in Assisting Butyrylcholinesterase Catalysis of Organophosphate Detoxification. Journal of Medicinal Chemistry 57:4, pages 1378-1389.
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Timo Wille, Horst Thiermann & Franz Worek. (2013) In vitro kinetics of nerve agent degradation by fresh frozen plasma (FFP). Archives of Toxicology 88:2, pages 301-307.
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Darren M. Roberts & Jonathan Brett. 2014. Basic and Clinical Toxicology of Organophosphorus Compounds. Basic and Clinical Toxicology of Organophosphorus Compounds 141 175 .
John D. Roback, Stephen Caldwell, Jeff Carson, Robertson Davenport, Mary Jo Drew, Anne Eder, Mark Fung, Marilyn Hamilton, John R. Hess, Naomi Luban, Jeremy G. Perkins, Bruce S. Sachais, Aryeh Shander, Toby Silverman, Ed Snyder, Christopher Tormey, John Waters & Ben Djulbegovic. (2010) Evidence-based practice guidelines for plasma transfusion. Transfusion 50:6, pages 1227-1239.
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Mohammad Hassan Murad, James R. Stubbs, Manish J. Gandhi, Amy T. Wang, Anu Paul, Patricia J. Erwin, Victor M. Montori & John D. Roback. (2010) The effect of plasma transfusion on morbidity and mortality: a systematic review and meta-analysis. Transfusion 50:6, pages 1370-1383.
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Wei Sun, Chunyuan Luo, Ramachandra S. Naik, Bhupendra P. Doctor & Ashima Saxena. (2009) Pharmacokinetics and immunologic consequences of repeated administrations of purified heterologous and homologous butyrylcholinesterase in mice. Life Sciences 85:17-18, pages 657-661.
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Patrick Masson & Daniel Rochu. 2009. Handbook of Toxicology of Chemical Warfare Agents. Handbook of Toxicology of Chemical Warfare Agents 1053 1065 .
Peter Eyer, Michael Eddleston, Horst Thiermann, Franz Worek & Nick A. Buckley. (2008) Are we using the right dose? - A tale of mole and gram. British Journal of Clinical Pharmacology 66:4, pages 451-452.
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J. V. PeterJ. L. MoranK. PichamuthuB. Chacko. (2008) Adjuncts and Alternatives to Oxime Therapy in Organophosphate Poisoning—is There Evidence of Benefit in Human Poisoning? A Review. Anaesthesia and Intensive Care 36:3, pages 339-350.
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Philip M. Alapat & Janice L. Zimmerman. (2008) Toxicology in the Critical Care Unit. Chest 133:4, pages 1006-1013.
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Michael Eddleston, Nick A Buckley, Peter Eyer & Andrew H Dawson. (2008) Management of acute organophosphorus pesticide poisoning. The Lancet 371:9612, pages 597-607.
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Chen-Chang Yang & Jou-Fang Deng. (2007) Intermediate Syndrome Following Organophosphate Insecticide Poisoning. Journal of the Chinese Medical Association 70:11, pages 467-472.
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Yen-Ta Huang, Pei-Chun Lai, Chien-Yu Su, Yi-Ting Chen, Chuan-Zhong Cai & Chih-Hsien Wang. (2007) Intermediate Syndrome After Organophosphate Ingestion. Tzu Chi Medical Journal 19:3, pages 159-163.
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F. Testud & J.-P. Grillet. (2007) Insecticides organophosphorés, carbamates, pyréthrinoïdes de synthèse et divers. EMC - Pathologie professionnelle et de l 'environnement 2:2, pages 1-24.
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CYNTHIA K. AARON. 2007. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose. Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose 1171 1184 .
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Richard K. Spence. (2006) Clinical use of plasma and plasma fractions. Best Practice & Research Clinical Haematology 19:1, pages 83-96.
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Javier Sáez-Valero, José A. Pérez de Gracia & Oksana Lockridge. (2005) Intraperitoneal administration of 340kDa human plasma butyrylcholinesterase increases the level of the enzyme in the cerebrospinal fluid of rats. Neuroscience Letters 383:1-2, pages 93-98.
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Óscar López, José G. Fernández-Bolaños & María Victoria Gil. (2005) New trends in pest control: the search for greener insecticides. Green Chemistry 7:6, pages 431.
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