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Research Article

Subchronic Toxicity of a Fluoroalkylethanol Mixture in Rats

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Pages 135-158 | Published online: 09 Oct 2008

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Judith C. Stadler, Donald A. Delker, Linda A. Malley, Steven R. Frame, Nancy E. Everds, Eve Mylchreest, Susan M. Munley, Scott E. Loveless & Robert C. Buck. (2008) Subchronic, Reproductive, and Developmental Toxicity of a Fluorotelomer-Based Urethane Polymeric Product. Drug and Chemical Toxicology 31:3, pages 317-337.
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Gregory S. Ladics, Gerald L. Kennedy, John O'Connor, Nancy Everds, Linda A. Malley, Steven R. Frame, Shawn Gannon, Reinhard Jung, Thomas Roth, Hiroyuki Iwai & Seiji Shin-ya. (2008) 90-Day Oral Gavage Toxicity Study of 8-2 Fluorotelomer Alcohol in Rats. Drug and Chemical Toxicology 31:2, pages 189-216.
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Articles from other publishers (20)

Keith A. Houck, Grace Patlewicz, Ann M. Richard, Antony J. Williams, Mahmoud A. Shobair, Marci Smeltz, M. Scott Clifton, Barbara Wetmore, Alex Medvedev & Sergei Makarov. (2021) Bioactivity profiling of per- and polyfluoroalkyl substances (PFAS) identifies potential toxicity pathways related to molecular structure. Toxicology 457, pages 152789.
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Nan Zhao, Meirong Zhao, Weiping Liu & Hangbiao Jin. (2021) Atmospheric particulate represents a source of C8–C12 perfluoroalkyl carboxylates and 10:2 fluorotelomer alcohol in tree bark. Environmental Pollution 273, pages 116475.
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Dongmei Chen, Ying Zhao, Wei Xu, Yuanhu Pan, Qu Wei & Shuyu Xie. (2020) Biotransformation and tissue bioaccumulation of 8:2 fluorotelomer alcohol in broiler by oral exposure. Environmental Pollution 267, pages 115611.
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Bevin E. Blake & Suzanne E. Fenton. (2020) Early life exposure to per- and polyfluoroalkyl substances (PFAS) and latent health outcomes: A review including the placenta as a target tissue and possible driver of peri- and postnatal effects. Toxicology 443, pages 152565.
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Hangbiao Jin, Lingling Mao, Jiahui Xie, Meirong Zhao, Xiaoxia Bai, Jie Wen, Tao Shen & Pengfei Wu. (2020) Poly- and perfluoroalkyl substance concentrations in human breast milk and their associations with postnatal infant growth. Science of The Total Environment 713, pages 136417.
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M.C. Huang, V.G. Robinson, S. Waidyanatha, A.L. Dzierlenga, M.J. DeVito, M.A. Eifrid, S.T. Gibbs & C.R. Blystone. (2019) Toxicokinetics of 8:2 fluorotelomer alcohol (8:2-FTOH) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration. Toxicology Reports 6, pages 924-932.
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John W. Stanifer, Heather M. Stapleton, Tomokazu Souma, Ashley Wittmer, Xinlu Zhao & L. Ebony Boulware. (2018) Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health. Clinical Journal of the American Society of Nephrology 13:10, pages 1479-1492.
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Amy A. Rand & Scott A. Mabury. (2017) Is there a human health risk associated with indirect exposure to perfluoroalkyl carboxylates (PFCAs)?. Toxicology 375, pages 28-36.
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Hermann Fromme, Annekatrin Dreyer, Silvio Dietrich, Ludwig Fembacher, Thomas Lahrz & Wolfgang Völkel. (2015) Neutral polyfluorinated compounds in indoor air in Germany – The LUPE 4 study. Chemosphere 139, pages 572-578.
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Pushkor Mukerji, Jessica Caverly Rae, Robert C. Buck & John C. O’Connor. (2015) Oral repeated-dose systemic and reproductive toxicity of 6:2 fluorotelomer alcohol in mice. Toxicology Reports 2, pages 130-143.
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Tessa Serex, Satheesh Anand, Susan Munley, E. Maria Donner, Steven R. Frame, Robert C. Buck & Scott E. Loveless. (2014) Toxicological evaluation of 6:2 fluorotelomer alcohol. Toxicology 319, pages 1-9.
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Penelope A. Rice, Omari J. Bandele & Paul Honigfort. 2014. Toxicants in Food Packaging and Household Plastics. Toxicants in Food Packaging and Household Plastics 177 203 .
Sathanandam S. Anand, Tessa L. Serex, Carol Carpenter, E. Maria Donner, Robert Hoke, Robert C. Buck & Scott E. Loveless. (2012) Toxicological assessment of tridecafluorohexylethyl methacrylate (6:2 FTMAC). Toxicology 292:1, pages 42-52.
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Scott E. Loveless, Brian Slezak, Tessa Serex, Joseph Lewis, Pushkor Mukerji, John C. O’Connor, E. Maria Donner, Steven R. Frame, Stephen H. Korzeniowski & Robert C. Buck. (2009) Toxicological evaluation of sodium perfluorohexanoate. Toxicology 264:1-2, pages 32-44.
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William J. Fasano, Lisa M. Sweeney, Michael P. Mawn, Diane L. Nabb, Bogdan Szostek, Robert C. Buck & Michael L. Gargas. (2009) Kinetics of 8-2 fluorotelomer alcohol and its metabolites, and liver glutathione status following daily oral dosing for 45 days in male and female rats. Chemico-Biological Interactions 180:2, pages 281-295.
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Claudia A.N. Kobayashi, Aline L. Leite, Thelma L. Silva, Lucilene D. Santos, Fábio C.S. Nogueira, Rodrigo C. Oliveira, Mario S. Palma, Gilberto B. Domont & Marília A.R. Buzalaf. (2009) Proteomic analysis of kidney in rats chronically exposed to fluoride. Chemico-Biological Interactions 180:2, pages 305-311.
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Diane L. Nabb, Bogdan Szostek, Matthew W. Himmelstein, Michael P. Mawn, Michael L. Gargas, Lisa M. Sweeney, Judith C. Stadler, Robert C. Buck & William J. Fasano. (2007) In Vitro Metabolism of 8-2 Fluorotelomer Alcohol: Interspecies Comparisons and Metabolic Pathway Refinement. Toxicological Sciences 100:2, pages 333-344.
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William J. Fasano, Stephen C. Carpenter, Shawn A. Gannon, Timothy A. Snow, Judith C. Stadler, Gerald L. Kennedy, Robert C. Buck, Stephen H. Korzeniowski, Paul M. Hinderliter & Raymond A. Kemper. (2006) Absorption, Distribution, Metabolism, and Elimination of 8-2 Fluorotelomer Alcohol in the Rat. Toxicological Sciences 91:2, pages 341-355.
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Marleen Maras, Caroline Vanparys, Frederik Muylle, Johan Robbens, Urs Berger, Jonathan L. Barber, Ronny Blust & Wim De Coen. (2006) Estrogen-Like Properties of Fluorotelomer Alcohols as Revealed by MCF-7 Breast Cancer Cell Proliferation. Environmental Health Perspectives 114:1, pages 100-105.
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Yuko Iwase, Naomi Kudo, Tomoaki Toyama, Masafumi Tamura, Atsushi Mitsumoto & Yoichi Kawashima. (2006) Effects of 8-2 Fluorotelomer Alcohol on Oleic Acid Formation in the Liver of Rats. Biological & Pharmaceutical Bulletin 29:8, pages 1740-1746.
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