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Drug Development and Industrial Pharmacy Volume 26, 2000 - Issue 6
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Research Article

Evaluation and Validation of a Fully Instrumented Hüttlin HKC 05-TJ Laboratory-Scale Fluidized Bed Granulator

K. Wöstheinrich Department of Pharmaceutical Technology, University of Tübingen, Auf der Morgenstelle 8, Tübingen, D-72076, Germany
&
P. C. Schmidt Department of Pharmaceutical Technology, University of Tübingen, Auf der Morgenstelle 8, Tübingen, D-72076, Germany
Pages 621-633 | Published online: 24 May 2000

Citations (8)

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Read on this site (3)

Zhi Hui Loh, Dawn ZL Er, Lai Wah Chan, Celine V Liew & Paul WS Heng. (2011) Spray granulation for drug formulation. Expert Opinion on Drug Delivery 8:12, pages 1645-1661.
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Oliver Schinzinger & Peter C. Schmidt. (2005) Comparison of the Granulation Behavior of Three Different Excipients in a Laboratory Fluidized Bed Granulator Using Statistical Methods. Pharmaceutical Development and Technology 10:2, pages 175-188.
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K. Wöstheinrich & P. C. Schmidt. (2001) Polymorphic Changes of Thiamine Hydrochloride During Granulation and Tableting. Drug Development and Industrial Pharmacy 27:6, pages 481-489.
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Articles from other publishers (5)

Guoqing Mu, Tao Liu, Junghui Chen, Liangzhi Xia & Caiyuan Yu. (2019) 110th Anniversary : Real-Time End Point Detection of Fluidized Bed Drying Process Based on a Switching Model of Near-Infrared Spectroscopy . Industrial & Engineering Chemistry Research 58:36, pages 16777-16786.
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Margot Fonteyne, Delphine Gildemyn, Elisabeth Peeters, Séverine Thérèse F.C. Mortier, Jurgen Vercruysse, Krist V. Gernaey, Chris Vervaet, Jean Paul Remon, Ingmar Nopens & Thomas De Beer. (2014) Moisture and drug solid-state monitoring during a continuous drying process using empirical and mass balance models. European Journal of Pharmaceutics and Biopharmaceutics 87:3, pages 616-628.
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Makoto Otsuka, Akira Koyama & Yusuke Hattori. (2014) Real-time release monitoring for water content and mean particle size of granules in lab-sized fluid-bed granulator by near-infrared spectroscopy. RSC Adv. 4:34, pages 17461-17468.
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Jukka Rantanen, Anna Jørgensen, Eetu Räsänen, Pirjo Luukkonen, Sari Airaksinen, Johanna Raiman, Kaisa Hänninen, Osmo Antikainen & Jouko Yliruusi. (2001) Process analysis of fluidized bed granulation. AAPS PharmSciTech 2:4, pages 13-20.
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E.I Keleb, A Vermeire, C Vervaet & J.P Remon. (2001) Cold extrusion as a continuous single-step granulation and tabletting process. European Journal of Pharmaceutics and Biopharmaceutics 52:3, pages 359-368.
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