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Research Article

Influence of Tableting Forces and Lubricant Concentration on the Adhesion Strength in Complex Layer Tablets

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Pages 745-754 | Published online: 06 May 2000

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Jason Franck, Admassu Abebe, Rekha Keluskar, Kyle Martin, Antara Majumdar, Niranjan Kottala & Howard Stamato. (2015) Axial strength test for round flat faced versus capsule shaped bilayer tablets. Pharmaceutical Development and Technology 20:2, pages 139-145.
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Articles from other publishers (24)

J. Simão, S.A. Chaudhary & A.J. Ribeiro. (2023) Implementation of Quality by Design (QbD) for development of bilayer tablets. European Journal of Pharmaceutical Sciences 184, pages 106412.
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Muneeba Akhtar, Muhammad Jamshaid, Muhammad Zaman & Agha Zeeshan Mirza. (2020) Bilayer tablets: A developing novel drug delivery system. Journal of Drug Delivery Science and Technology 60, pages 102079.
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Tomasz Blicharski, Katarzyna Swiader, Anna Serefko, Sylwia Kulczycka-Mamona, Michal Kolodziejczyk & Aleksandra Szopa. (2019) Challenges in technology of bilayer and multi-layer tablets: a mini-review. Current Issues in Pharmacy and Medical Sciences 32:4, pages 229-235.
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Brahma N. Singh. (2019) Product Development, Manufacturing, and Packaging of Solid Dosage Forms Under QbD and PAT Paradigm: DOE Case Studies for Industrial Applications. AAPS PharmSciTech 20:8.
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Marco Bellini, Mathias Walther & Roland Bodmeier. (2019) Evaluation of manufacturing process parameters causing multilayer tablets delamination. International Journal of Pharmaceutics 570, pages 118607.
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Jianyi Zhang, Chuan-Yu Wu, David Storey & Gerard Byrne. (2018) Interfacial strength of bilayer pharmaceutical tablets. Powder Technology 337, pages 36-42.
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Jing Tao, Sophia Robertson-Lavalle, Preetanshu Pandey & Sherif Badawy. (2017) Understanding the Delamination Risk of a Trilayer Tablet Using Minipiloting Tools. Journal of Pharmaceutical Sciences 106:11, pages 3346-3352.
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V. Mazel, H. Diarra, V. Busignies & P. Tchoreloff. (2017) Shear strength of pharmaceutical tablets: Theoretical considerations, evaluation and relation with the capping tendency of biconvex tablets. International Journal of Pharmaceutics 532:1, pages 421-426.
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J.M. Rowe & F. Nikfar. 2017. Predictive Modeling of Pharmaceutical Unit Operations. Predictive Modeling of Pharmaceutical Unit Operations 229 251 .
Luca Castrati, Vincent Mazel, Virginie Busignies, Harona Diarra, Alessandra Rossi, Paolo Colombo & Pierre Tchoreloff. (2016) Comparison of breaking tests for the characterization of the interfacial strength of bilayer tablets. International Journal of Pharmaceutics 513:1-2, pages 709-716.
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Virginie Busignies, Vincent Mazel, Harona Diarra & Pierre Tchoreloff. (2014) Development of a new test for the easy characterization of the adhesion at the interface of bilayer tablets: Proof-of-concept study by experimental design. International Journal of Pharmaceutics 477:1-2, pages 476-484.
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Admassu Abebe, Ilgaz Akseli, Omar Sprockel, Niranjan Kottala & Alberto M. Cuitiño. (2014) Review of bilayer tablet technology. International Journal of Pharmaceutics 461:1-2, pages 549-558.
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Virginie Busignies, Vincent Mazel, Harona Diarra & Pierre Tchoreloff. (2013) Role of the elasticity of pharmaceutical materials on the interfacial mechanical strength of bilayer tablets. International Journal of Pharmaceutics 457:1, pages 260-267.
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Niranjan Kottala, Admassu Abebe, Omar Sprockel, James Bergum, Faranak Nikfar & Alberto M. Cuitiño. (2012) Evaluation of the Performance Characteristics of Bilayer Tablets: Part I. Impact of Material Properties and Process Parameters on the Strength of Bilayer Tablets. AAPS PharmSciTech 13:4, pages 1236-1242.
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Fridrun Podczeck. (2012) Methods for the practical determination of the mechanical strength of tablets—From empiricism to science. International Journal of Pharmaceutics 436:1-2, pages 214-232.
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Niranjan Kottala, Admassu Abebe, Omar Sprockel, Ilgaz Akseli, Faranak Nikfar & Alberto M. Cuitiño. (2012) Influence of compaction properties and interfacial topography on the performance of bilayer tablets. International Journal of Pharmaceutics 436:1-2, pages 171-178.
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Fridrun Podczeck & Emad Al-Muti. (2010) The tensile strength of bilayered tablets made from different grades of microcrystalline cellulose. European Journal of Pharmaceutical Sciences 41:3-4, pages 483-488.
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Sivakumar R. Vaithiyalingam & Vilayat A. Sayeed. (2010) Critical factors in manufacturing multi-layer tablets—Assessing material attributes, in-process controls, manufacturing process and product performance. International Journal of Pharmaceutics 398:1-2, pages 9-13.
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Siracha Tuntikulwattana, Ampol Mitrevej, Teerakiat Kerdcharoen, Desmond B. Williams & Nuttanan Sinchaipanid. (2010) Development and Optimization of Micro/Nanoporous Osmotic Pump Tablets. AAPS PharmSciTech 11:2, pages 924-935.
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Chuan-Yu Wu & Jonathan P.K. Seville. (2009) A comparative study of compaction properties of binary and bilayer tablets. Powder Technology 189:2, pages 285-294.
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Deng Guang Yu, Li-Min Zhu, Christopher J. Branford-White & Xiang Liang Yang. (2008) Three-Dimensional Printing in Pharmaceutics: Promises and Problems. Journal of Pharmaceutical Sciences 97:9, pages 3666-3690.
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Kazuyuki Shimizu, Masaki Ando & Yukiharu Nakayama. (2007) Characterization of Tableting using the OSDRC System. Pharmaceutical Research 24:10, pages 1902-1909.
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F. Podczeck, K.R. Drake, J.M. Newton & I. Haririan. (2006) The strength of bilayered tablets. European Journal of Pharmaceutical Sciences 29:5, pages 361-366.
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S ABDUL & S PODDAR. (2004) A flexible technology for modified release of drugs: multi layered tablets. Journal of Controlled Release 97:3, pages 393-405.
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